Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
BCL2 1件: BCL2 💬
|
Venetoclax Venetoclax 💬
| Venetoclax | 028 1件: 28 💬
|
| 2 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 3 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
BRAF 5件: BRAF, FLT4, KDR, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 4 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR 1件: EGFR 💬
|
Cetuximab Cetuximab 💬
| Cetuximab | 051 2件: 51, 86 💬
|
| 5 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR 1件: EGFR 💬
|
Erlotinib Erlotinib 💬
| Erlotinib | 094 1件: 94 💬
|
| 6 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR 1件: EGFR 💬
|
Gefitinib Gefitinib 💬
| Gefitinib | 075 1件: 75 💬
|
| 7 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR 1件: EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 1件: 34 💬
|
| 8 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR 2件: EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 3件: 34, 74, 75 💬
|
| 9 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR 2件: EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 1件: 34 💬
|
| 10 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR 4件: EGFR, ERBB2, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 1件: 67 💬
|
| 11 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 3件: FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 1件: 34 💬
|
| 12 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 3件: FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 1件: 34 💬
|
| 13 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬
|
| 14 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 2件: 28, 34 💬
|
| 15 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FYN 3件: FYN, PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 2件: 51, 85 💬
|
| 16 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FYN 3件: FYN, PDGFRB, SRC 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 2件: 51, 85 💬
|
| 17 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
IGF1R 1件: IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 1件: 232 💬
|
| 18 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
| 19 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
IGF1R 1件: IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 1件: 51 💬
|
| 20 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
ITGA4 1件: ITGA4 💬
|
Firategrast Firategrast 💬
| Firategrast | 013 1件: 13 💬
|
| 21 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
ITGA4 1件: ITGA4 💬
|
Natalizumab Natalizumab 💬
| Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬
|
| 22 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
ITGA4 2件: ITGA4, ITGB7 💬
|
Abrilumab Abrilumab 💬
| Abrilumab | 096 2件: 96, 97 💬
|
| 23 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
ITGA4 2件: ITGA4, ITGB7 💬
|
Vedolizumab Vedolizumab 💬
| Vedolizumab | 094 3件: 94, 96, 97 💬
|
| 24 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
ITGB7 1件: ITGB7 💬
|
Etrolizumab Etrolizumab 💬
| Etrolizumab | 096 2件: 96, 97 💬
|
| 25 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
KDR 2件: KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 1件: 34 💬
|
| 26 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 1件: MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 1件: 34 💬
|
| 27 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 1件: MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
| 28 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 1件: MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 1件: 34 💬
|
| 29 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 1件: MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 1件: 34 💬
|
| 30 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 1件: MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
| 31 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
PDGFRA 1件: PDGFRA 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
| 32 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
PDGFRA 2件: PDGFRA, PDGFRB 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬
|
| 33 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
PGF 3件: PGF, VEGFA, VEGFB 💬
|
Aflibercept Aflibercept 💬
| Aflibercept | 090 2件: 90, 166 💬
|
| 34 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
PIK3CA 1件: PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 1件: 138 💬
|
| 35 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 2件: 53, 65 💬
|
| 36 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
PIK3CD 1件: PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 3件: 35, 53, 61 💬
|
| 37 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
PRKCB 1件: PRKCB 💬
|
Enzastaurin Enzastaurin 💬
| Enzastaurin | 168 1件: 168 💬
|
| 38 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
ROCK1 2件: ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 4件: 2 , 5 , 7 , 51 💬
|
| 39 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
ROCK2 1件: ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 2件: 51, 85 💬
|
| 40 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
SRC 1件: SRC 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 2件: 2 , 67 💬
|
| 41 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
SRC 1件: SRC 💬
|
Saracatinib Saracatinib 💬
| Saracatinib | 006 3件: 6 , 89, 272 💬
|
| 42 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬
|
| 43 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
VEGFA 1件: VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
|
| 44 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
VWF 1件: VWF 💬
|
Caplacizumab Caplacizumab 💬
| Caplacizumab | 064 1件: 64 💬
|