Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Th1 and Th2 cell differentiation 💬
3件: CD3D, CD3E, CD3G 💬 D05092 💬 Muromonab 3件: 60, 96, 97 💬
2 Th1 and Th2 cell differentiation 💬
3件: CD3D, CD3E, CD3G 💬 D08959 💬 Otelixizumab 1件: 46 💬
3 Th1 and Th2 cell differentiation 💬
3件: CD3D, CD3E, CD3G 💬 D06314 💬 Visilizumab 2件: 96, 97 💬
4 Th1 and Th2 cell differentiation 💬
1件: CD3E 💬 D11463 💬 Mosunetuzumab 1件: 49 💬
5 Th1 and Th2 cell differentiation 💬
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 D04318 💬 Glatiramer 4件:  2 , 13, 96, 156 💬
6 Th1 and Th2 cell differentiation 💬
1件: IFNG 💬 D11120 💬 Emapalumab 2件: 49, 107 💬
7 Th1 and Th2 cell differentiation 💬
1件: IFNG 💬 D04242 💬 Fontolizumab 1件: 46 💬
8 Th1 and Th2 cell differentiation 💬
2件: IFNGR1, IFNGR2 💬 D00747 💬 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326 💬
9 Th1 and Th2 cell differentiation 💬
2件: IL12A, IL12B 💬 D09214 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
10 Th1 and Th2 cell differentiation 💬
1件: IL13 💬 D08857 💬 Anrukinzumab 1件: 97 💬
11 Th1 and Th2 cell differentiation 💬
1件: IL13 💬 D09633 💬 Lebrikizumab 1件: 85 💬
12 Th1 and Th2 cell differentiation 💬
1件: IL13 💬 D09979 💬 Tralokinumab 2件: 85, 97 💬
13 Th1 and Th2 cell differentiation 💬
1件: IL2RA 💬 D03058 💬 Basiliximab 6件:  2 , 50, 66, 97, 222, 228 💬
14 Th1 and Th2 cell differentiation 💬
1件: IL2RA 💬 D03639 💬 Daclizumab 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬
15 Th1 and Th2 cell differentiation 💬
3件: IL2RA, IL2RB, IL2RG 💬 D00748 💬 Aldesleukin 6件:  2 , 35, 49, 65, 96, 97 💬
16 Th1 and Th2 cell differentiation 💬
1件: IL4 💬 D03117 💬 Binetrakin 1件: 46 💬
17 Th1 and Th2 cell differentiation 💬
1件: IL4R 💬 D10354 💬 Dupilumab 4件: 51, 98, 160, 162 💬
18 Th1 and Th2 cell differentiation 💬
1件: IL5 💬 D04923 💬 Mepolizumab 4件: 44, 45, 98, 162 💬
19 Th1 and Th2 cell differentiation 💬
1件: IL5 💬 D08985 💬 Reslizumab 2件: 44, 98 💬
20 Th1 and Th2 cell differentiation 💬
1件: JAK1 💬 D10871 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬
21 Th1 and Th2 cell differentiation 💬
1件: JAK1 💬 D10944 💬 Itacitinib 5件: 46, 51, 60, 97, 228 💬
22 Th1 and Th2 cell differentiation 💬
1件: JAK1 💬 D10994 💬 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
23 Th1 and Th2 cell differentiation 💬
2件: JAK1, JAK2 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
24 Th1 and Th2 cell differentiation 💬
2件: JAK1, JAK2 💬 D09959 💬 Ruxolitinib 1件: 228 💬
25 Th1 and Th2 cell differentiation 💬
3件: JAK1, JAK2, JAK3 💬 D10653 💬 Peficitinib 1件: 46 💬
26 Th1 and Th2 cell differentiation 💬
4件: JAK1, JAK2, JAK3, TYK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
27 Th1 and Th2 cell differentiation 💬
1件: LCK 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
28 Th1 and Th2 cell differentiation 💬
1件: LCK 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
29 Th1 and Th2 cell differentiation 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
30 Th1 and Th2 cell differentiation 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
31 Th1 and Th2 cell differentiation 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
32 Th1 and Th2 cell differentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
33 Th1 and Th2 cell differentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus 1件: 160 💬
34 Th1 and Th2 cell differentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
35 Th1 and Th2 cell differentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
36 Th1 and Th2 cell differentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin 1件: 222 💬
37 Th1 and Th2 cell differentiation 💬
1件: PRKCQ 💬 D09671 💬 Sotrastaurin 1件: 97 💬
38 Th1 and Th2 cell differentiation 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
39 Th1 and Th2 cell differentiation 💬
1件: TYK2 💬 D11817 💬 Deucravacitinib 2件: 96, 97 💬