Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 MAPK12 62件: Endocrine resistance 💬, MAPK signaling pathway 💬, Rap1 signaling pathway 💬, FoxO signaling pathway 💬, Sphingolipid signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Adrenergic signaling in cardiomyocytes 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, Signaling pathways regulating pluripotency of stem cells 💬, Platelet activation 💬, Neutrophil extracellular trap formation 💬, Toll-like receptor signaling pathway 💬, NOD-like receptor signaling pathway 💬, RIG-I-like receptor signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, Fc epsilon RI signaling pathway 💬, TNF signaling pathway 💬, Leukocyte transendothelial migration 💬, Thermogenesis 💬, Neurotrophin signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Dopaminergic synapse 💬, Inflammatory mediator regulation of TRP channels 💬, GnRH signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Prolactin signaling pathway 💬, Relaxin signaling pathway 💬, Non-alcoholic fatty liver disease 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Growth hormone synthesis, secretion and action 💬, Alcoholic liver disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Epithelial cell signaling in Helicobacter pylori infection 💬, Pathogenic Escherichia coli infection 💬, Shigellosis 💬, Salmonella infection 💬, Pertussis 💬, Yersinia infection 💬, Leishmaniasis 💬, Chagas disease 💬, Toxoplasmosis 💬, Tuberculosis 💬, Hepatitis B 💬, Human cytomegalovirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Epstein-Barr virus infection 💬, Human immunodeficiency virus 1 infection 💬, Coronavirus disease - COVID-19 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - reactive oxygen species 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Diabetic cardiomyopathy 💬, Lipid and atherosclerosis 💬, Fluid shear stress and atherosclerosis 💬 D09639 Losmapimod 2件: 113, 222
2 MAPK12 62件: Endocrine resistance 💬, MAPK signaling pathway 💬, Rap1 signaling pathway 💬, FoxO signaling pathway 💬, Sphingolipid signaling pathway 💬, Oocyte meiosis 💬, Cellular senescence 💬, Adrenergic signaling in cardiomyocytes 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, Signaling pathways regulating pluripotency of stem cells 💬, Platelet activation 💬, Neutrophil extracellular trap formation 💬, Toll-like receptor signaling pathway 💬, NOD-like receptor signaling pathway 💬, RIG-I-like receptor signaling pathway 💬, C-type lectin receptor signaling pathway 💬, IL-17 signaling pathway 💬, Th1 and Th2 cell differentiation 💬, Th17 cell differentiation 💬, T cell receptor signaling pathway 💬, Fc epsilon RI signaling pathway 💬, TNF signaling pathway 💬, Leukocyte transendothelial migration 💬, Thermogenesis 💬, Neurotrophin signaling pathway 💬, Retrograde endocannabinoid signaling 💬, Dopaminergic synapse 💬, Inflammatory mediator regulation of TRP channels 💬, GnRH signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Prolactin signaling pathway 💬, Relaxin signaling pathway 💬, Non-alcoholic fatty liver disease 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Growth hormone synthesis, secretion and action 💬, Alcoholic liver disease 💬, Amyotrophic lateral sclerosis 💬, Prion disease 💬, Pathways of neurodegeneration - multiple diseases 💬, Epithelial cell signaling in Helicobacter pylori infection 💬, Pathogenic Escherichia coli infection 💬, Shigellosis 💬, Salmonella infection 💬, Pertussis 💬, Yersinia infection 💬, Leishmaniasis 💬, Chagas disease 💬, Toxoplasmosis 💬, Tuberculosis 💬, Hepatitis B 💬, Human cytomegalovirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Epstein-Barr virus infection 💬, Human immunodeficiency virus 1 infection 💬, Coronavirus disease - COVID-19 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - reactive oxygen species 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Diabetic cardiomyopathy 💬, Lipid and atherosclerosis 💬, Fluid shear stress and atherosclerosis 💬 D10959 Neflamapimod 1件: 8