Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Thyroid hormone signaling pathway 💬
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin 1件: 299 💬
2 Thyroid hormone signaling pathway 💬
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digoxin 💬 Digoxin 3件:  8 , 46, 210 💬
3 Thyroid hormone signaling pathway 💬
1件: CASP9 💬 Rimiducid 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
4 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Clomifene 💬 Clomifene 1件: 74 💬
5 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Danazol 💬 Danazol 5件: 60, 63, 64, 65, 285 💬
6 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Desogestrel 💬 Desogestrel 1件: 230 💬
7 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
8 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
9 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Estradiol 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬
10 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Estradiol valerate 💬 Estradiol valerate 1件: 65 💬
11 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Estriol 💬 Estriol 2件: 13, 227 💬
12 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Estriol tripropionate 💬 Estriol 2件: 13, 227 💬
13 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol 4件: 13, 46, 49, 299 💬
14 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Fulvestrant 💬 Fulvestrant 2件: 49, 86 💬
15 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Mestranol 💬 Mestranol 2件: 46, 49 💬
16 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
17 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Raloxifene 💬 Raloxifene 1件: 46 💬
18 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Tamoxifen 💬 Tamoxifen 3件:  2 , 113, 227 💬
19 Thyroid hormone signaling pathway 💬
3件: HDAC1, HDAC2, HDAC3 💬 Vorinostat 💬 Vorinostat 2件: 75, 96 💬
20 Thyroid hormone signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
21 Thyroid hormone signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
22 Thyroid hormone signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 1件: 34 💬
23 Thyroid hormone signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
24 Thyroid hormone signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 4件:  2 , 34, 279, 280 💬
25 Thyroid hormone signaling pathway 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
26 Thyroid hormone signaling pathway 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
27 Thyroid hormone signaling pathway 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬
28 Thyroid hormone signaling pathway 💬
1件: MYH7 💬 Mavacamten 💬 Mavacamten 1件: 58 💬
29 Thyroid hormone signaling pathway 💬
1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬
30 Thyroid hormone signaling pathway 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
31 Thyroid hormone signaling pathway 💬
1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
32 Thyroid hormone signaling pathway 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
33 Thyroid hormone signaling pathway 💬
1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
34 Thyroid hormone signaling pathway 💬
3件: RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin 1件: 37 💬
35 Thyroid hormone signaling pathway 💬
3件: RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin 1件: 49 💬
36 Thyroid hormone signaling pathway 💬
3件: RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene 2件: 13, 75 💬
37 Thyroid hormone signaling pathway 💬
1件: SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬
38 Thyroid hormone signaling pathway 💬
1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
39 Thyroid hormone signaling pathway 💬
1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
40 Thyroid hormone signaling pathway 💬
1件: SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬
41 Thyroid hormone signaling pathway 💬
2件: THRA, THRB 💬 Levothyroxine 💬 Levothyroxine 5件: 19, 49, 78, 80, 222 💬
42 Thyroid hormone signaling pathway 💬
2件: THRA, THRB 💬 Liothyronine 💬 Liothyronine 4件: 13, 78, 210, 212 💬
43 Thyroid hormone signaling pathway 💬
2件: THRA, THRB 💬 Tiratricol 💬 Tiratricol 2件: 78, 139 💬
44 Thyroid hormone signaling pathway 💬
1件: THRB 💬 Sobetirome 💬 Sobetirome 1件: 20 💬