Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Oxytocin 💬 [1] Oxytocin[2] Oxytocin; Syntocinon; [1] OXTR 💬[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[7] 6, 72, 127, 168, 193, 206, 226 💬
2 Albendazole 💬 [1] Albendazole[2] Albendazole; Eskazole; --[1] 96 💬
3 Valproic acid 💬 [1] Valproic acid[3] Valproate; VALPROATE SODIUM; Valproic acid; [7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[10] 2, 3, 5, 26, 65, 90, 102, 222, 233, 256 💬
4 Tolcapone 💬 [1] Tolcapone[3] Tasmar; Tolcapon; Tolcapone; [1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[3] 6, 28, 127 💬
5 Lithium carbonate 💬 [1] Lithium carbonate[2] Lithium; LITHIUM CARBONATE; --[5] 2, 13, 17, 18, 127 💬
6 Methylene blue 💬 [1] Methylene blue[2] METHYLENE BLUE; Methylthioninium chloride; --[2] 97, 127 💬
7 Phenothiazine 💬 [1] Phenothiazine[1] Phenothiazine; --[1] 127 💬
8 Amiodarone 💬 [1] Amiodarone[1] AMIODARONE; [16] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[32] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 28, 127 💬
9 Galantamine 💬 [1] Galantamine[2] Galantamine; Galantamine hydrobromide; [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[2] 6, 127 💬
10 Metformin 💬 [1] Metformin[5] Metformin; Metformin HCl; Metformin hydrochloride; Metformina; Metformine; [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
11 Nabilone 💬 [1] Nabilone[1] Nabilone; [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[3] 6, 13, 127 💬
12 Amantadine 💬 [1] Amantadine[3] AMANTADINE; AMANTADINE HYDROCHLORIDE; GOCOVRI; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[4] 6, 8, 13, 127 💬
13 Citalopram 💬 [1] Citalopram[1] Citalopram; [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127 💬
14 Donepezil 💬 [1] Donepezil[3] Aricept; Donepezil; Donepezil hydrochloride; [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
15 Memantine 💬 [1] Memantine[3] EBIXA; Memantine; MEMANTINE HYDROCHLORIDE; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206 💬
16 Davunetide 💬 [1] Davunetide[1] Davunetide; --[3] 5, 7, 127 💬
17 Methylthioninium chloride hydrate 💬 [1] Methylene blue[2] METHYLENE BLUE; Methylthioninium chloride; --[2] 97, 127 💬
18 Censavudine 💬 [1] Censavudine[1] CENSAVUDINE; --[2] 2, 127 💬
19 Flortaucipir F 18 💬 [1] Flortaucipir[1] Flortaucipir; [1] MAPT 💬[4] Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[3] 5, 7, 127 💬
20 Hydromethylthionine mesylate 💬 [1] Hydromethylthionine mesylate[1] LMTM; [1] MAPT 💬[4] Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[1] 127 💬
21 Verdiperstat 💬 [1] Verdiperstat[1] Verdiperstat; [1] MPO 💬[5] Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagosome, Transcriptional misregulation in cancer 💬[3] 2, 17, 127 💬
22 Latozinemab 💬 [1] Latozinemab[2] AL001; Latozinemab; [1] SORT1 💬[3] Cholesterol metabolism, Lysosome, Neurotrophin signaling pathway 💬[2] 2, 127 💬