Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Hydrocortisone 💬 [1] Hydrocortisone[6] Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
2 Corticotropin 💬 [1] Corticotropin[5] ACTH; Acthar; Adrenocorticotropic hormone; Corticotrophin; Corticotropin; [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[12] 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
3 Dexamethasone 💬 [1] Dexamethasone[5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[22] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
4 Nifedipine 💬 [1] Nifedipine[1] Nifedipine; [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 50, 81 💬
5 Prednisolone 💬 [1] Prednisolone[3] Prednisolona; Prednisolone; Prednisolonum; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
6 Prednisone 💬 [1] Prednisone[3] PREDNISONA; Prednisone; RAYOS; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
7 Flutamide 💬 [1] Flutamide[1] Flutamide; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 81 💬
8 Letrozole 💬 [1] Letrozole[1] Letrozole; [1] CYP19A1 💬[3] Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[2] 81, 89 💬
9 Cortisone acetate 💬 [1] Cortisone acetate[1] Cortisone acetate; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
10 Hydrocortisone cypionate 💬 [1] Hydrocortisone cypionate[1] Cortef; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 6, 81, 83 💬
11 Hydrocortisone succinate 💬 [1] Hydrocortisone succinate[2] HYDROCORTISONE HYDROGEN SUCCINATE; Solu-Cortef; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 6, 81, 83 💬
12 Sodium acetate 💬 [1] Sodium acetate[1] Sodium Acetate; --[2] 81, 251 💬
13 Metformin 💬 [1] Metformin[5] Metformin; Metformin HCl; Metformin Hydrochloride; Metformina; Metformine; [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
14 Cortisone 💬 [1] Cortisone[1] Cortisone; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
15 Fludrocortisone 💬 [1] Fludrocortisone[1] Fludrocortisone; [1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[3] 6, 17, 81 💬
16 Pioglitazone 💬 [1] Pioglitazone[1] Pioglitazone; [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
17 Nevanimibe 💬 [1] Nevanimibe[1] Nevanimibe; --[2] 75, 81 💬