Pregabalin    (DrugBank: Pregabalin)

5 diseases
告示番号疾患名(ページ内リンク)臨床試験数
13多発性硬化症/視神経脊髄炎3
36表皮水疱症1
46悪性関節リウマチ1
70広範脊柱管狭窄症6
298遺伝性膵炎4

13. 多発性硬化症/視神経脊髄炎 [臨床試験数:3,050,薬物数:2,147(DrugBank:348),標的遺伝子数:244,標的パスウェイ数:228
Searched query = "Multiple sclerosis/Neuromyelitis optica", "Multiple sclerosis", "Neuromyelitis optica", "MS", "NMOSD", "Devic disease", "Balo concentric sclerosis", "Baló concentric sclerosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
3 / 3,050 trials found
No.TrialIDDate_
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1JPRN-JapicCTI-101335
01/9/201008/11/2010An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic PainAn Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic Pain (Post Spinal Cord Injury Pain, Post Stroke Pain, And Multiple Sclerosis Pain) Spinal Cord Diseases, Spinal Cord Injuries, Neuralgia, PainIntervention name : pregabalin
INN of the intervention : pregabalin
Dosage And administration of the intervention : pregabalin capsules 150mg/day, 300mg/day, 450mg/day or 600mg/day BID
Control intervention name : null
Pfizer Japan Inc.NULL18BOTH100Phase 3NULL
2NCT01202227
(ClinicalTrials.gov)
September 201031/8/2010An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic PainAn Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic Pain (Post Spinal Cord Injury Pain, Post Stroke Pain, And Multiple Sclerosis Pain)Spinal Cord Diseases;Spinal Cord Injuries;Neuralgia;PainDrug: pregabalinPfizerNULLCompleted18 YearsN/AAll104Phase 3Japan
3NCT00291148
(ClinicalTrials.gov)
March 200610/2/2006Neuropathic Pain Assessment Comparing Pregabalin and Paroxetine in Management of MS-induced Neuropathic PainA Comparative Single Center, Randomized Neuropathic Pain Assessment Study Involving Patients With Clinically Definite Multiple Sclerosis (MS) Receiving Treatment With Either Pregabalin or ParoxetineNeuropathic Pain;Multiple SclerosisDrug: paroxetine;Drug: pregabalin;Drug: ParoxetineUniversity of ManitobaNULLCompleted18 Years65 YearsBoth75Phase 3Canada

36. 表皮水疱症 [臨床試験数:147,薬物数:170(DrugBank:40),標的遺伝子数:32,標的パスウェイ数:113
Searched query = "Epidermolysis bullosa", "EBS", "JEB", "DDEB", "RDEB", "Kindler syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 147 trial found
No.TrialIDDate_
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1NCT03928093
(ClinicalTrials.gov)
August 7, 201927/3/2019Pregabalin Treatment for RDEB Pain and ItchA Double-blind, Randomized, Cross-over, Feasibility Trial of Pregabalin for the Treatment of Recessive Dystrophic Epidermolysis Bullosa-associated Neuropathic Pain and ItchPain, Neuropathic;Itch;Epidermolysis BullosaDrug: PregabalinThe Hospital for Sick ChildrenEpidemolysis Bullosa Research PartnershipRecruiting8 Years40 YearsAll15Phase 3Canada

46. 悪性関節リウマチ [臨床試験数:4,183,薬物数:2,538(DrugBank:401),標的遺伝子数:183,標的パスウェイ数:219
Searched query = "Malignant rheumatoid arthritis", "Rheumatoid arthritis", "Rheumatoid arthritis with vasculitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 4,183 trial found
No.TrialIDDate_
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1JPRN-jRCTs041180071
13/10/201607/03/2019T-ReX studyTocilizumab treatment with Reducing and stopping methotreXate in patients with rheumatoid arthritis in stable low disease activity-state - T-ReX study Rheumatoid arthritisAt week 0, the dosing frequency of MTX was decreased from weekly to biweekly without a change in dose, regardless of the initial dose. At week 12, MTX was discontinued if low disease activity was maintained. TCZ and csDMARDs other than MTX were continued at a stable dose and interval throughout the course of the study. Glucocorticoids were continued at a stable dose up to week 36, and allowed to taper after week 36. The use of oral analgesics (non-steroidal anti-inflammatory drugs, acetaminophen, pregabalin, and tramadol) was not prohibited during the study period. One or more of the following rescue treatments were performed if the CDAI score was >10 and at the discretion of the investigator and/or upon patient request: changing the dosing frequency back to weekly administration, restarting, or increasing doses of MTX; increasing doses of or adding csDMARDs other than MTX or glucocorticoids; and administering an intraarticular injection of corticosteroids, hyaluronic acid, or lidocaine.Kojima ToshihisaNULLComplete>= 20age oldNot applicableBoth51N/AJapan

70. 広範脊柱管狭窄症 [臨床試験数:91,薬物数:195(DrugBank:54),標的遺伝子数:60,標的パスウェイ数:85
Searched query = "Spinal stenosis", "Extensive spinal canal stenosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
6 / 91 trials found
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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PhaseCountries
1ChiCTR2000028775
2020-02-012020-01-03Safety and effectiveness of pregabalin in the management of postoperative pain in lumbar surgerySafety and effectiveness of pregabalin in the management of postoperative pain in lumbar surgery 1. Lumbar disc herniation; 2. Lumbar spinal stenosis; 3. Lumbar spondylolisthesisPregabalin group: ?????????? ?????????? Postoperative analgesia with pregabalin;Celecoxib group: Postoperative analgesia with celecoxib;The First Affiliated Hospital of Chongqing Medical UniversityNULLRecruiting1880BothPregabalin group:60;Celecoxib group:60;China
2NCT03584074
(ClinicalTrials.gov)
July 1, 201829/6/2018Clinical Trial of Pregabalin and COX2 in Spinal StenosisComparative Study for Decrease of Pain Intensity and Pain Sensitivity Between Pregabalin + COX-2 Inhibitor and COX-2 Inhibitor in Patients With Lumbar Spinal Stenosis: Randomized Controlled TrialSpinal Stenosis LumbarDrug: Pregabalin 75mg;Drug: Celebrex 200Mg CapsuleSeoul National University Bundang HospitalNULLUnknown status40 YearsN/AAll60Phase 4NULL
3NCT01888536
(ClinicalTrials.gov)
February 201325/6/2013A Study to Evaluate Efficacy of ?Opast Tablet?for Neurologic Claudication in Patients With Lumbar Spinal StenosisA Randomized, Double-Blind, Comparative, Multi-Center, Phase ? Clinical Trial to Evaluate Efficacy of ?Opast Tablet?for Neurologic Claudication in Patients With Lumbar Spinal StenosisNeurologic Claudication in Patients With Lumbar Spinal StenosisDrug: Limaprost;Drug: Pregabalin;Drug: Placebo(for Pregabalin);Drug: Placebo(for Limaprost)Yungjin Pharm. Co., Ltd.NULLCompleted20 Years75 YearsBoth182Phase 4Korea, Republic of
4JPRN-UMIN000007419
2012/04/0101/04/2012A Prospective, Randomized, Multicenter Trial of Pregabalin and Celecoxib for Lumbar Spinal Stenosis Lumbar Spinal StenosisCelecoxib

Pregabalin
Department of Orthopedic Surgery Kobe University Graduate School of MedicineNULLPending50years-old90years-oldMale and Female80Not selectedJapan
5NCT00908375
(ClinicalTrials.gov)
May 200921/5/2009Efficacy of Pregabalin in Patients With Radicular PainEfficacy of Pregabalin in Patients With Radicular PainNeuropathy; Radicular, Lumbar, Lumbosacral;Failed Back Surgery Syndrome;Spinal Stenosis;Herniated DiscDrug: Pregabalin;Drug: Sugar PillNorthwestern UniversityNULLCompleted18 Years64 YearsAll39Phase 4United States
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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6NCT00638443
(ClinicalTrials.gov)
March 200812/3/2008Lumbar Stenosis Outcomes Research (LUSTOR)Lumbar Stenosis Outcomes Research (LUSTOR)- A Randomized, Double-blind, Cross-over Trial of Pregabalin vs. Diphenhydramine in Patients With Lumbar Spinal Stenosis and Neuropathic Low Back PainLumbar Spinal StenosisDrug: Pregabalin;Drug: DiphenhydramineUniversity of RochesterPfizerCompleted50 YearsN/AAll29Phase 4United States

298. 遺伝性膵炎 [臨床試験数:93,薬物数:168(DrugBank:51),標的遺伝子数:48,標的パスウェイ数:134
Searched query = "Hereditary pancreatitis", "Chronic pancreatitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
4 / 93 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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sponsor
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agemin
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1NCT01528540
(ClinicalTrials.gov)
April 201227/1/2012Evaluation of Efficacy of Combination of Pregabalin and Antioxidant in Reducing Pain in Chronic Pancreatitis: a Randomized Control TrialEvaluation of Efficacy of Combination of Pregabalin and Antioxidant in Reducing Pain in Chronic Pancreatitis: a RCTChronic PancreatitisDrug: Placebo;Drug: Antioxidant plus PregabalinAsian Institute of Gastroenterology, IndiaNULLCompleted18 Years65 YearsBoth87N/AIndia
2EUCTR2009-010266-28-NL
(EUCTR)
21/07/200929/01/2009Een gerandomiseerde dubbelblinde, placebogecontroleerde, klinische parallelle groep studie van pregabaline in patiënten met chronische pancreatitis - Effect van pregabaline therapie bij patiënten met chronische pancreatitisEen gerandomiseerde dubbelblinde, placebogecontroleerde, klinische parallelle groep studie van pregabaline in patiënten met chronische pancreatitis - Effect van pregabaline therapie bij patiënten met chronische pancreatitis chronische pancreatitis
MedDRA version: 9.1;Level: LLT;Classification code 10009093;Term: Chronic pancreatitis
Trade Name: Lyrica® Afdeling heelkunde, Universitair Medisch Centrum Sint RadboudNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
30Netherlands
3NCT00755573
(ClinicalTrials.gov)
October 200818/9/2008Pain and Chronic Pancreatitis - Clinical End Experimental StudiesA Randomized, Double-Blind, Placebo-Controlled, Parallel Group Clinical and Experimental Pilot Study of Pregabalin in Patients With Chronic PancreatitisChronic PancreatitisDrug: Pregabalin;Drug: placeboAalborg UniversitetshospitalRadboud UniversityCompleted18 Years75 YearsBoth64Phase 2/Phase 3Denmark;Netherlands
4EUCTR2008-002671-27-DK
(EUCTR)
14/07/200830/05/2008A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL GROUP CLINICAL AND EXPERIMENTAL PILOTSTUDY OF PREGABALIN IN PATIENTS WITH CHRONIC PANCREATITISA RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL GROUP CLINICAL AND EXPERIMENTAL PILOTSTUDY OF PREGABALIN IN PATIENTS WITH CHRONIC PANCREATITIS Chronic pancreatitis
MedDRA version: 9.1;Level: LLT;Classification code 10033649;Term: Pancreatitis chronic
Trade Name: Lyrica
INN or Proposed INN: pregabalin
INN or Proposed INN: Pregabalin
Department of Medical GastroenterologyNULLNot RecruitingFemale: yes
Male: yes
45Phase 3Denmark