Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 ABC transporters 💬
 1件: ABCC8 💬 Diazoxide 💬 Diazoxide 2件: 13, 193 💬 💬
2 Acute myeloid leukemia 💬
 1件: KIT 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
3 Acute myeloid leukemia 💬
 1件: KIT 💬 Masitinib 💬 Masitinib 6件:  2 ,  5 ,  6 , 13, 46, 96 💬 💬
4 Acute myeloid leukemia 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
5 Acute myeloid leukemia 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
6 Acute myeloid leukemia 💬
 1件: RARA 💬 Vitamin A 💬 Vitamin A 3件: 13, 53, 90 💬 💬
7 Adipocytokine signaling pathway 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
8 Adipocytokine signaling pathway 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
9 Adipocytokine signaling pathway 💬
 2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
10 Adipocytokine signaling pathway 💬
 3件: RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene 2件: 13, 75 💬 💬
11 Adipocytokine signaling pathway 💬
 1件: TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
12 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRA1A 💬 Alfuzosin 💬 Alfuzosin 1件: 13 💬 💬
13 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRA1A 💬 Silodosin 💬 Silodosin 2件:  6 , 13 💬 💬
14 Adrenergic signaling in cardiomyocytes 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin 💬 Tamsulosin 1件: 13 💬 💬
15 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB2 💬 Clenbuterol 💬 Clenbuterol 5件:  1 ,  2 ,  6 , 13, 256 💬 💬
16 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB2 💬 Isoxsuprine 💬 Isoxsuprine 1件: 13 💬 💬
17 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB2 💬 Albuterol 💬 Salbutamol 12件:  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬
18 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
19 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Gabapentin 💬 Gabapentin 5件:  6 , 13, 19, 70, 298 💬 💬
20 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Pregabalin 💬 Pregabalin 5件: 13, 36, 46, 70, 298 💬 💬
21 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Carbamazepine 💬 Carbamazepine 3件:  6 , 13, 231 💬 💬
22 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Lamotrigine 💬 Lamotrigine 5件: 13, 34, 38, 114, 144 💬 💬
23 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Lidocaine 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬
24 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Lidocaine hydrochloride monohydrate 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬
25 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Oxcarbazepine 💬 Oxcarbazepine 1件: 13 💬 💬
26 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Phenytoin 💬 Phenytoin 1件: 13 💬 💬
27 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Quinidine 💬 Quinidine 3件:  2 ,  8 , 13 💬 💬
28 African trypanosomiasis 💬
 4件: IL10, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
29 AGE-RAGE signaling pathway in diabetic complications 💬
 5件: CCL2, IL1A, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
30 AGE-RAGE signaling pathway in diabetic complications 💬
 1件: VEGFA 💬 Bevacizumab 💬 Bevacizumab 6件: 13, 34, 85, 87, 227, 280 💬 💬
31 Alanine, aspartate and glutamate metabolism 💬
 4件: ABAT, ALDH5A1, GAD1, GAD2 💬 Valproic acid 💬 Valproic acid 14件:  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬
32 Alcoholic liver disease 💬
 1件: C5 💬 Eculizumab 💬 Eculizumab 7件: 11, 13, 14, 61, 62, 109, 222 💬 💬
33 Alcoholic liver disease 💬
 1件: C5 💬 Ravulizumab 💬 Ravulizumab 7件:  2 , 11, 13, 50, 62, 66, 109 💬 💬
34 Alcoholic liver disease 💬
 1件: IL17A 💬 Secukinumab 💬 Secukinumab 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 💬
35 Alcoholic liver disease 💬
 3件: IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
36 Alcoholic liver disease 💬
 2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
37 Alcoholism 💬
 2件: ADORA2A, ADORA2B 💬 Adenosine 💬 Adenosine 3件: 13, 58, 65 💬 💬
38 Alcoholism 💬
 1件: DDC 💬 Carbidopa 💬 Carbidopa 7件:  6 , 13, 17, 90, 140, 164, 201 💬 💬
39 Alcoholism 💬
 1件: DRD2 💬 Domperidone 💬 Domperidone 5件:  6 , 13, 17, 51, 230 💬 💬
40 Alcoholism 💬
 1件: DRD2 💬 Domperidone maleate 💬 Domperidone 5件:  6 , 13, 17, 51, 230 💬 💬
41 Alcoholism 💬
 1件: DRD2 💬 Quetiapine 💬 Quetiapine 2件:  6 , 13 💬 💬
42 Alcoholism 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amantadine 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬 💬
43 Alcoholism 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
44 Alcoholism 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
45 Alcoholism 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
46 Alcoholism 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
47 Alcoholism 💬
 1件: SLC6A3 💬 Armodafinil 💬 Armodafinil 3件:  6 , 13, 84 💬 💬
48 Alcoholism 💬
 1件: SLC6A3 💬 Lisdexamfetamine 💬 Lisdexamfetamine 1件: 13 💬 💬
49 Alcoholism 💬
 1件: SLC6A3 💬 Methylphenidate 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬 💬
50 Aldosterone synthesis and secretion 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
51 Aldosterone synthesis and secretion 💬
 3件: CACNA1G, CACNA1H, CACNA1I 💬 Valproic acid 💬 Valproic acid 14件:  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬
52 Aldosterone synthesis and secretion 💬
 1件: MC2R 💬 Corticotropin 💬 Corticotropin 12件:  2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬
53 Aldosterone-regulated sodium reabsorption 💬
 3件: SCNN1A, SCNN1B, SCNN1G 💬 Amiloride 💬 Amiloride 4件: 13, 67, 225, 299 💬 💬
54 Allograft rejection 💬
 2件: CD80, CD86 💬 Abatacept 💬 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬
55 Allograft rejection 💬
 2件: IL10, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
56 Alzheimer disease 💬
 4件: APH1A, NCSTN, PSEN1, PSENEN 💬 Tarenflurbil 💬 Tarenflurbil 1件: 13 💬 💬
57 Alzheimer disease 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
58 Alzheimer disease 💬
 3件: CHRM1, CHRM3, CHRM5 💬 Oxybutynin 💬 Oxybutynin 3件:  6 , 13, 53 💬 💬
59 Alzheimer disease 💬
 1件: CHRM3 💬 Darifenacin 💬 Darifenacin 2件:  6 , 13 💬 💬
60 Alzheimer disease 💬
 1件: CHRM3 💬 Solifenacin 💬 Solifenacin 3件:  6 , 13, 53 💬 💬
61 Alzheimer disease 💬
 1件: CHRNA7 💬 Nicotine 💬 Nicotine 3件:  6 , 13, 84 💬 💬
62 Alzheimer disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amantadine 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬 💬
63 Alzheimer disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
64 Alzheimer disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
65 Alzheimer disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
66 Alzheimer disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
67 Alzheimer disease 💬
 4件: IL1A, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
68 Alzheimer disease 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
69 Alzheimer disease 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
70 Alzheimer disease 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
71 Alzheimer disease 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
72 Alzheimer disease 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬
73 Alzheimer disease 💬
 1件: PSMB5 💬 Ixazomib 💬 Ixazomib 5件: 13, 16, 28, 51, 61 💬 💬
74 Alzheimer disease 💬
 1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
75 Alzheimer disease 💬
 1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
76 Alzheimer disease 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
77 Alzheimer disease 💬
 1件: PTGS2 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬 💬
78 Alzheimer disease 💬
 1件: PTGS2 💬 Ibuprofen 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬 💬
79 Alzheimer disease 💬
 1件: PTGS2 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬 💬
80 Amoebiasis 💬
 4件: IL10, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
81 Amoebiasis 💬
 2件: IL1R1, IL1R2 💬 Anakinra 💬 Anakinra 18件:  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬
82 Amphetamine addiction 💬
 2件: CACNA1C, CACNA1D 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
83 Amphetamine addiction 💬
 1件: DDC 💬 Carbidopa 💬 Carbidopa 7件:  6 , 13, 17, 90, 140, 164, 201 💬 💬
84 Amphetamine addiction 💬
 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
85 Amphetamine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amantadine 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬 💬
86 Amphetamine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
87 Amphetamine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
88 Amphetamine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
89 Amphetamine addiction 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
90 Amphetamine addiction 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
91 Amphetamine addiction 💬
 1件: SLC6A3 💬 Armodafinil 💬 Armodafinil 3件:  6 , 13, 84 💬 💬
92 Amphetamine addiction 💬
 1件: SLC6A3 💬 Lisdexamfetamine 💬 Lisdexamfetamine 1件: 13 💬 💬
93 Amphetamine addiction 💬
 1件: SLC6A3 💬 Methylphenidate 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬 💬
94 AMPK signaling pathway 💬
 1件: ADRA1A 💬 Alfuzosin 💬 Alfuzosin 1件: 13 💬 💬
95 AMPK signaling pathway 💬
 1件: ADRA1A 💬 Silodosin 💬 Silodosin 2件:  6 , 13 💬 💬
96 AMPK signaling pathway 💬
 1件: ADRA1A 💬 Tamsulosin 💬 Tamsulosin 1件: 13 💬 💬
97 AMPK signaling pathway 💬
 1件: HMGCR 💬 Atorvastatin 💬 Atorvastatin 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬
98 AMPK signaling pathway 💬
 1件: HMGCR 💬 Pravastatin 💬 Pravastatin 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 💬
99 AMPK signaling pathway 💬
 1件: HMGCR 💬 Simvastatin 💬 Simvastatin 21件:  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬
100 AMPK signaling pathway 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
101 AMPK signaling pathway 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
102 AMPK signaling pathway 💬
 1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
103 AMPK signaling pathway 💬
 2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
104 Amyotrophic lateral sclerosis 💬
 7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
105 Amyotrophic lateral sclerosis 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amantadine 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬 💬
106 Amyotrophic lateral sclerosis 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
107 Amyotrophic lateral sclerosis 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
108 Amyotrophic lateral sclerosis 💬
 6件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
109 Amyotrophic lateral sclerosis 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
110 Amyotrophic lateral sclerosis 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
111 Amyotrophic lateral sclerosis 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
112 Amyotrophic lateral sclerosis 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
113 Amyotrophic lateral sclerosis 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬
114 Amyotrophic lateral sclerosis 💬
 1件: PSMB5 💬 Ixazomib 💬 Ixazomib 5件: 13, 16, 28, 51, 61 💬 💬
115 Amyotrophic lateral sclerosis 💬
 1件: TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
116 Antifolate resistance 💬
 2件: DHFR, DHFR2 💬 Methotrexate 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬
117 Antifolate resistance 💬
 3件: IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
118 Antigen processing and presentation 💬
 1件: TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
119 Apelin signaling pathway 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
120 Apelin signaling pathway 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
121 Apelin signaling pathway 💬
 1件: PDE3B 💬 Ibudilast 💬 Ibudilast 2件:  2 , 13 💬 💬
122 Apelin signaling pathway 💬
 2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
123 Apoptosis 💬
 1件: TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
124 Arachidonic acid metabolism 💬
 2件: PTGS1, PTGS2 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
125 Arachidonic acid metabolism 💬
 2件: PTGS1, PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
126 Arachidonic acid metabolism 💬
 2件: PTGS1, PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
127 Arachidonic acid metabolism 💬
 2件: PTGS1, PTGS2 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬 💬
128 Arachidonic acid metabolism 💬
 2件: PTGS1, PTGS2 💬 Ibuprofen 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬 💬
129 Arachidonic acid metabolism 💬
 2件: PTGS1, PTGS2 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬 💬
130 Arrhythmogenic right ventricular cardiomyopathy 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
131 Arrhythmogenic right ventricular cardiomyopathy 💬
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Gabapentin 💬 Gabapentin 5件:  6 , 13, 19, 70, 298 💬 💬
132 Arrhythmogenic right ventricular cardiomyopathy 💬
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Pregabalin 💬 Pregabalin 5件: 13, 36, 46, 70, 298 💬 💬
133 Arrhythmogenic right ventricular cardiomyopathy 💬
 1件: ITGA4 💬 Firategrast 💬 Firategrast 1件: 13 💬 💬
134 Arrhythmogenic right ventricular cardiomyopathy 💬
 1件: ITGA4 💬 Natalizumab 💬 Natalizumab 6件: 13, 15, 25, 46, 63, 96 💬 💬
135 Asthma 💬
 2件: IL10, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
136 Autoimmune thyroid disease 💬
 2件: CD80, CD86 💬 Abatacept 💬 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬
137 Autoimmune thyroid disease 💬
 1件: IL10 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
138 Autophagy - animal 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
139 Autophagy - animal 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
140 Autophagy - animal 💬
 2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬
141 Autophagy - other 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
142 Autophagy - other 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
143 Axon guidance 💬
 1件: ABL1 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
144 Axon guidance 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
145 Axon guidance 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
146 Axon guidance 💬
 1件: RGMA 💬 Elezanumab 💬 Elezanumab 1件: 13 💬 💬
147 B cell receptor signaling pathway 💬
 1件: BTK 💬 Evobrutinib 💬 Evobrutinib 3件: 13, 46, 49 💬 💬
148 B cell receptor signaling pathway 💬
 1件: BTK 💬 Fenebrutinib 💬 Fenebrutinib 1件: 13 💬 💬
149 B cell receptor signaling pathway 💬
 1件: BTK 💬 Orelabrutinib 💬 Orelabrutinib 4件: 13, 49, 61, 63 💬 💬
150 B cell receptor signaling pathway 💬
 1件: BTK 💬 Remibrutinib 💬 Remibrutinib 2件: 13, 53 💬 💬
151 B cell receptor signaling pathway 💬
 1件: BTK 💬 Zanubrutinib 💬 Zanubrutinib 5件: 13, 63, 222, 300, 331 💬 💬
152 B cell receptor signaling pathway 💬
 1件: CD19 💬 Inebilizumab 💬 Inebilizumab 4件: 11, 13, 51, 300 💬 💬
153 B cell receptor signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
154 B cell receptor signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
155 beta-Alanine metabolism 💬
 3件: ABAT, GAD1, GAD2 💬 Valproic acid 💬 Valproic acid 14件:  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬
156 Bile secretion 💬
 1件: CA2 💬 Acetazolamide 💬 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 💬
157 Bile secretion 💬
 1件: HMGCR 💬 Atorvastatin 💬 Atorvastatin 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬
158 Bile secretion 💬
 1件: HMGCR 💬 Pravastatin 💬 Pravastatin 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 💬
159 Bile secretion 💬
 1件: HMGCR 💬 Simvastatin 💬 Simvastatin 21件:  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬
160 Bile secretion 💬
 1件: RXRA 💬 Bexarotene 💬 Bexarotene 2件: 13, 75 💬 💬
161 Biosynthesis of cofactors 💬
 2件: DHFR, DHFR2 💬 Methotrexate 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬
162 Biosynthesis of cofactors 💬
 1件: DHODH 💬 Teriflunomide 💬 Teriflunomide 3件: 13, 25, 26 💬 💬
163 Biosynthesis of cofactors 💬
 2件: NQO1, VKORC1 💬 Warfarin 💬 Warfarin 11件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 💬
164 Bladder cancer 💬
 1件: VEGFA 💬 Bevacizumab 💬 Bevacizumab 6件: 13, 34, 85, 87, 227, 280 💬 💬
165 Breast cancer 💬
 1件: ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol 4件: 13, 46, 49, 299 💬 💬
166 Breast cancer 💬
 2件: ESR1, ESR2 💬 Estradiol 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬 💬
167 Breast cancer 💬
 2件: ESR1, ESR2 💬 Estriol 💬 Estriol 2件: 13, 227 💬 💬
168 Breast cancer 💬
 2件: ESR1, ESR2 💬 Estriol tripropionate 💬 Estriol 2件: 13, 227 💬 💬
169 Breast cancer 💬
 1件: KIT 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
170 Breast cancer 💬
 1件: KIT 💬 Masitinib 💬 Masitinib 6件:  2 ,  5 ,  6 , 13, 46, 96 💬 💬
171 Breast cancer 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
172 Breast cancer 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
173 Breast cancer 💬
 1件: PGR 💬 Dydrogesterone 💬 Dydrogesterone 1件: 13 💬 💬
174 Breast cancer 💬
 1件: PGR 💬 Levonorgestrel 💬 Levonorgestrel 1件: 13 💬 💬
175 Breast cancer 💬
 1件: PGR 💬 Medroxyprogesterone acetate 💬 Medroxyprogesterone acetate 8件: 13, 35, 46, 49, 50, 51, 60, 107 💬 💬
176 Breast cancer 💬
 1件: PGR 💬 Nomegestrol 💬 Nomegestrol 1件: 13 💬 💬
177 Breast cancer 💬
 1件: PGR 💬 Nomegestrol acetate 💬 Nomegestrol acetate 1件: 13 💬 💬
178 Breast cancer 💬
 1件: PGR 💬 Norethindrone 💬 Norethisterone 4件: 13, 46, 49, 299 💬 💬
179 Butanoate metabolism 💬
 4件: ABAT, ALDH5A1, GAD1, GAD2 💬 Valproic acid 💬 Valproic acid 14件:  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬
180 C-type lectin receptor signaling pathway 💬
 4件: IL10, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
181 C-type lectin receptor signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
182 C-type lectin receptor signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
183 C-type lectin receptor signaling pathway 💬
 1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
184 C-type lectin receptor signaling pathway 💬
 1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
185 C-type lectin receptor signaling pathway 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
186 C-type lectin receptor signaling pathway 💬
 1件: PTGS2 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬 💬
187 C-type lectin receptor signaling pathway 💬
 1件: PTGS2 💬 Ibuprofen 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬 💬
188 C-type lectin receptor signaling pathway 💬
 1件: PTGS2 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬 💬
189 Caffeine metabolism 💬
 1件: XDH 💬 Febuxostat 💬 Febuxostat 3件:  2 ,  6 , 13 💬 💬
190 Calcium signaling pathway 💬
 2件: ADORA2A, ADORA2B 💬 Adenosine 💬 Adenosine 3件: 13, 58, 65 💬 💬
191 Calcium signaling pathway 💬
 1件: ADRA1A 💬 Alfuzosin 💬 Alfuzosin 1件: 13 💬 💬
192 Calcium signaling pathway 💬
 1件: ADRA1A 💬 Silodosin 💬 Silodosin 2件:  6 , 13 💬 💬
193 Calcium signaling pathway 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin 💬 Tamsulosin 1件: 13 💬 💬
194 Calcium signaling pathway 💬
 1件: ADRB2 💬 Clenbuterol 💬 Clenbuterol 5件:  1 ,  2 ,  6 , 13, 256 💬 💬
195 Calcium signaling pathway 💬
 1件: ADRB2 💬 Isoxsuprine 💬 Isoxsuprine 1件: 13 💬 💬
196 Calcium signaling pathway 💬
 1件: ADRB2 💬 Albuterol 💬 Salbutamol 12件:  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬
197 Calcium signaling pathway 💬
 1件: ADRB3 💬 Mirabegron 💬 Mirabegron 4件:  6 , 13, 53, 226 💬 💬
198 Calcium signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
199 Calcium signaling pathway 💬
 3件: CACNA1G, CACNA1H, CACNA1I 💬 Valproic acid 💬 Valproic acid 14件:  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬
200 Calcium signaling pathway 💬
 1件: CD38 💬 Daratumumab 💬 Daratumumab 5件: 13, 28, 48, 49, 63 💬 💬
201 Calcium signaling pathway 💬
 4件: CHRM1, CHRM2, CHRM3, CHRM5 💬 Oxybutynin 💬 Oxybutynin 3件:  6 , 13, 53 💬 💬
202 Calcium signaling pathway 💬
 1件: CHRM3 💬 Darifenacin 💬 Darifenacin 2件:  6 , 13 💬 💬
203 Calcium signaling pathway 💬
 1件: CHRM3 💬 Solifenacin 💬 Solifenacin 3件:  6 , 13, 53 💬 💬
204 Calcium signaling pathway 💬
 1件: CHRNA7 💬 Nicotine 💬 Nicotine 3件:  6 , 13, 84 💬 💬
205 Calcium signaling pathway 💬
 1件: CYSLTR1 💬 Ibudilast 💬 Ibudilast 2件:  2 , 13 💬 💬
206 Calcium signaling pathway 💬
 1件: CYSLTR1 💬 Montelukast 💬 Montelukast 8件:  6 , 13, 46, 61, 63, 85, 98, 228 💬 💬
207 Calcium signaling pathway 💬
 1件: FGFR2 💬 Palifermin 💬 Palifermin 5件: 13, 36, 38, 39, 65 💬 💬
208 Calcium signaling pathway 💬
 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 Amantadine 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬 💬
209 Calcium signaling pathway 💬
 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
210 Calcium signaling pathway 💬
 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
211 Calcium signaling pathway 💬
 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
212 Calcium signaling pathway 💬
 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
213 Calcium signaling pathway 💬
 1件: HRH1 💬 Cetirizine 💬 Cetirizine 4件: 13, 28, 35, 300 💬 💬
214 Calcium signaling pathway 💬
 1件: HRH1 💬 Clemastine 💬 Clemastine 1件: 13 💬 💬
215 Calcium signaling pathway 💬
 1件: HRH1 💬 Desloratadine 💬 Desloratadine 1件: 13 💬 💬
216 Calcium signaling pathway 💬
 1件: HRH1 💬 Dexchlorpheniramine 💬 Dexchlorpheniramine 2件: 13, 49 💬 💬
217 Calcium signaling pathway 💬
 1件: HRH1 💬 Diphenhydramine 💬 Diphenhydramine 8件: 11, 13, 49, 51, 70, 86, 222, 256 💬 💬
218 Calcium signaling pathway 💬
 1件: HRH1 💬 Fexofenadine 💬 Fexofenadine 2件: 13, 46 💬 💬
219 Calcium signaling pathway 💬
 1件: HRH1 💬 Loratadine 💬 Loratadine 4件: 13, 46, 89, 98 💬 💬
220 Calcium signaling pathway 💬
 1件: HRH2 💬 Ranitidine 💬 Ranitidine 2件: 13, 65 💬 💬
221 Calcium signaling pathway 💬
 1件: HTR2A 💬 Quetiapine 💬 Quetiapine 2件:  6 , 13 💬 💬
222 Calcium signaling pathway 💬
 2件: HTR2A, HTR4 💬 Cisapride 💬 Cisapride 1件: 13 💬 💬
223 Calcium signaling pathway 💬
 2件: HTR2A, HTR4 💬 Cisapride 💬 Cisapride 1件: 13 💬 💬
224 Calcium signaling pathway 💬
 1件: HTR4 💬 Prucalopride 💬 Prucalopride 3件: 13, 51, 96 💬 💬
225 Calcium signaling pathway 💬
 1件: PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
226 Calcium signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
227 Calcium signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
228 Calcium signaling pathway 💬
 1件: TBXA2R 💬 Ramatroban 💬 Ramatroban 1件: 13 💬 💬
229 Calcium signaling pathway 💬
 1件: VEGFA 💬 Bevacizumab 💬 Bevacizumab 6件: 13, 34, 85, 87, 227, 280 💬 💬
230 cAMP signaling pathway 💬
 2件: ADORA1, ADORA2A 💬 Adenosine 💬 Adenosine 3件: 13, 58, 65 💬 💬
231 cAMP signaling pathway 💬
 1件: ADRB2 💬 Clenbuterol 💬 Clenbuterol 5件:  1 ,  2 ,  6 , 13, 256 💬 💬
232 cAMP signaling pathway 💬
 1件: ADRB2 💬 Isoxsuprine 💬 Isoxsuprine 1件: 13 💬 💬
233 cAMP signaling pathway 💬
 1件: ADRB2 💬 Albuterol 💬 Salbutamol 12件:  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬
234 cAMP signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
235 cAMP signaling pathway 💬
 2件: CHRM1, CHRM2 💬 Oxybutynin 💬 Oxybutynin 3件:  6 , 13, 53 💬 💬
236 cAMP signaling pathway 💬
 1件: DRD2 💬 Domperidone 💬 Domperidone 5件:  6 , 13, 17, 51, 230 💬 💬
237 cAMP signaling pathway 💬
 1件: DRD2 💬 Domperidone maleate 💬 Domperidone 5件:  6 , 13, 17, 51, 230 💬 💬
238 cAMP signaling pathway 💬
 1件: DRD2 💬 Quetiapine 💬 Quetiapine 2件:  6 , 13 💬 💬
239 cAMP signaling pathway 💬
 2件: GABBR1, GABBR2 💬 Arbaclofen 💬 Arbaclofen 2件: 13, 206 💬 💬
240 cAMP signaling pathway 💬
 2件: GABBR1, GABBR2 💬 Arbaclofen placarbil 💬 Arbaclofen Placarbil 1件: 13 💬 💬
241 cAMP signaling pathway 💬
 2件: GABBR1, GABBR2 💬 Baclofen 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
242 cAMP signaling pathway 💬
 1件: GLP1R 💬 Dulaglutide 💬 Dulaglutide 2件: 13, 299 💬 💬
243 cAMP signaling pathway 💬
 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
244 cAMP signaling pathway 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amantadine 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬 💬
245 cAMP signaling pathway 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
246 cAMP signaling pathway 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
247 cAMP signaling pathway 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
248 cAMP signaling pathway 💬
 1件: HTR4 💬 Cisapride 💬 Cisapride 1件: 13 💬 💬
249 cAMP signaling pathway 💬
 1件: HTR4 💬 Cisapride 💬 Cisapride 1件: 13 💬 💬
250 cAMP signaling pathway 💬
 1件: HTR4 💬 Prucalopride 💬 Prucalopride 3件: 13, 51, 96 💬 💬
251 cAMP signaling pathway 💬
 1件: MC2R 💬 Corticotropin 💬 Corticotropin 12件:  2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬
252 cAMP signaling pathway 💬
 6件: PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Ibudilast 💬 Ibudilast 2件:  2 , 13 💬 💬
253 cAMP signaling pathway 💬
 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 Rolipram 💬 Rolipram 2件:  8 , 13 💬 💬
254 Carbohydrate digestion and absorption 💬
 1件: CACNA1D 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
255 Carbohydrate digestion and absorption 💬
 2件: TAS1R2, TAS1R3 💬 Aspartame 💬 Aspartame 4件:  6 , 13, 67, 86 💬 💬
256 Cardiac muscle contraction 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
257 Cardiac muscle contraction 💬
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Gabapentin 💬 Gabapentin 5件:  6 , 13, 19, 70, 298 💬 💬
258 Cardiac muscle contraction 💬
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Pregabalin 💬 Pregabalin 5件: 13, 36, 46, 70, 298 💬 💬
259 Cell adhesion molecules 💬
 2件: CD80, CD86 💬 Abatacept 💬 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬
260 Cell adhesion molecules 💬
 1件: ITGA4 💬 Firategrast 💬 Firategrast 1件: 13 💬 💬
261 Cell adhesion molecules 💬
 1件: ITGA4 💬 Natalizumab 💬 Natalizumab 6件: 13, 15, 25, 46, 63, 96 💬 💬
262 Cell adhesion molecules 💬
 1件: ITGAL 💬 Efalizumab 💬 Efalizumab 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 💬
263 Cell adhesion molecules 💬
 1件: PDCD1 💬 Nivolumab 💬 Nivolumab 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 💬
264 Cell cycle 💬
 1件: ABL1 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
265 Cellular senescence 💬
 1件: CACNA1D 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
266 Cellular senescence 💬
 2件: IL1A, IL6 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
267 Cellular senescence 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
268 Cellular senescence 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
269 Cellular senescence 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
270 Cellular senescence 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
271 Central carbon metabolism in cancer 💬
 1件: FGFR2 💬 Palifermin 💬 Palifermin 5件: 13, 36, 38, 39, 65 💬 💬
272 Central carbon metabolism in cancer 💬
 1件: KIT 💬 Masitinib 💬 Masitinib 6件:  2 ,  5 ,  6 , 13, 46, 96 💬 💬
273 Central carbon metabolism in cancer 💬
 2件: KIT, PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
274 Central carbon metabolism in cancer 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
275 Central carbon metabolism in cancer 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
276 cGMP-PKG signaling pathway 💬
 2件: ADORA1, ADORA3 💬 Adenosine 💬 Adenosine 3件: 13, 58, 65 💬 💬
277 cGMP-PKG signaling pathway 💬
 1件: ADRA1A 💬 Alfuzosin 💬 Alfuzosin 1件: 13 💬 💬
278 cGMP-PKG signaling pathway 💬
 1件: ADRA1A 💬 Silodosin 💬 Silodosin 2件:  6 , 13 💬 💬
279 cGMP-PKG signaling pathway 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin 💬 Tamsulosin 1件: 13 💬 💬
280 cGMP-PKG signaling pathway 💬
 3件: ADRA2A, ADRA2B, ADRA2C 💬 Brimonidine 💬 Brimonidine 2件: 13, 90 💬 💬
281 cGMP-PKG signaling pathway 💬
 3件: ADRA2A, ADRA2B, ADRA2C 💬 Guanabenz 💬 Guanabenz 2件:  2 , 13 💬 💬
282 cGMP-PKG signaling pathway 💬
 3件: ADRA2A, ADRA2B, ADRA2C 💬 Tizanidine 💬 Tizanidine 1件: 13 💬 💬
283 cGMP-PKG signaling pathway 💬
 1件: ADRB2 💬 Clenbuterol 💬 Clenbuterol 5件:  1 ,  2 ,  6 , 13, 256 💬 💬
284 cGMP-PKG signaling pathway 💬
 1件: ADRB2 💬 Isoxsuprine 💬 Isoxsuprine 1件: 13 💬 💬
285 cGMP-PKG signaling pathway 💬
 1件: ADRB2 💬 Albuterol 💬 Salbutamol 12件:  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬
286 cGMP-PKG signaling pathway 💬
 1件: ADRB3 💬 Mirabegron 💬 Mirabegron 4件:  6 , 13, 53, 226 💬 💬
287 cGMP-PKG signaling pathway 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
288 cGMP-PKG signaling pathway 💬
 1件: OPRD1 💬 Loperamide 💬 Loperamide 2件: 13, 97 💬 💬
289 cGMP-PKG signaling pathway 💬
 1件: OPRD1 💬 Naltrexone 💬 Naltrexone 13件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 💬
290 cGMP-PKG signaling pathway 💬
 1件: OPRD1 💬 Oxycodone 💬 Oxycodone 5件:  6 , 13, 70, 226, 298 💬 💬
291 cGMP-PKG signaling pathway 💬
 2件: PDE3A, PDE3B 💬 Ibudilast 💬 Ibudilast 2件:  2 , 13 💬 💬
292 cGMP-PKG signaling pathway 💬
 1件: PDE5A 💬 Vardenafil 💬 Vardenafil 3件: 13, 86, 299 💬 💬
293 cGMP-PKG signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
294 cGMP-PKG signaling pathway 💬
 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
295 Chagas disease 💬
 5件: CCL2, IL10, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
296 Chemical carcinogenesis - DNA adducts 💬
 1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
297 Chemical carcinogenesis - DNA adducts 💬
 1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
298 Chemical carcinogenesis - DNA adducts 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
299 Chemical carcinogenesis - DNA adducts 💬
 1件: PTGS2 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬 💬
300 Chemical carcinogenesis - DNA adducts 💬
 1件: PTGS2 💬 Ibuprofen 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬 💬
301 Chemical carcinogenesis - DNA adducts 💬
 1件: PTGS2 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬 💬
302 Chemical carcinogenesis - reactive oxygen species 💬
 1件: ABL1 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
303 Chemical carcinogenesis - reactive oxygen species 💬
 1件: KEAP1 💬 Dimethyl fumarate 💬 Dimethyl fumarate 5件: 13, 49, 51, 86, 296 💬 💬
304 Chemical carcinogenesis - reactive oxygen species 💬
 1件: NQO1 💬 Warfarin 💬 Warfarin 11件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 💬
305 Chemical carcinogenesis - reactive oxygen species 💬
 1件: VEGFA 💬 Bevacizumab 💬 Bevacizumab 6件: 13, 34, 85, 87, 227, 280 💬 💬
306 Chemical carcinogenesis - receptor activation 💬
 1件: ADRB2 💬 Clenbuterol 💬 Clenbuterol 5件:  1 ,  2 ,  6 , 13, 256 💬 💬
307 Chemical carcinogenesis - receptor activation 💬
 1件: ADRB2 💬 Isoxsuprine 💬 Isoxsuprine 1件: 13 💬 💬
308 Chemical carcinogenesis - receptor activation 💬
 1件: ADRB2 💬 Albuterol 💬 Salbutamol 12件:  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬
309 Chemical carcinogenesis - receptor activation 💬
 1件: ADRB3 💬 Mirabegron 💬 Mirabegron 4件:  6 , 13, 53, 226 💬 💬
310 Chemical carcinogenesis - receptor activation 💬
 1件: AR 💬 Testosterone 💬 Testosterone 8件:  1 ,  2 ,  3 , 13, 60, 76, 78, 113 💬 💬
311 Chemical carcinogenesis - receptor activation 💬
 1件: AR 💬 Testosterone undecanoate 💬 Testosterone undecanoate 2件: 13, 60 💬 💬
312 Chemical carcinogenesis - receptor activation 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
313 Chemical carcinogenesis - receptor activation 💬
 6件: CHRNA3, CHRNA4, CHRNA7, CHRNA9, CHRNB2, CHRNB4 💬 Nicotine 💬 Nicotine 3件:  6 , 13, 84 💬 💬
314 Chemical carcinogenesis - receptor activation 💬
 1件: ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol 4件: 13, 46, 49, 299 💬 💬
315 Chemical carcinogenesis - receptor activation 💬
 2件: ESR1, ESR2 💬 Estradiol 💬 Estradiol 7件: 13, 46, 49, 65, 76, 226, 299 💬 💬
316 Chemical carcinogenesis - receptor activation 💬
 2件: ESR1, ESR2 💬 Estriol 💬 Estriol 2件: 13, 227 💬 💬
317 Chemical carcinogenesis - receptor activation 💬
 2件: ESR1, ESR2 💬 Estriol tripropionate 💬 Estriol 2件: 13, 227 💬 💬
318 Chemical carcinogenesis - receptor activation 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
319 Chemical carcinogenesis - receptor activation 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
320 Chemical carcinogenesis - receptor activation 💬
 1件: PGR 💬 Dydrogesterone 💬 Dydrogesterone 1件: 13 💬 💬
321 Chemical carcinogenesis - receptor activation 💬
 1件: PGR 💬 Levonorgestrel 💬 Levonorgestrel 1件: 13 💬 💬
322 Chemical carcinogenesis - receptor activation 💬
 1件: PGR 💬 Medroxyprogesterone acetate 💬 Medroxyprogesterone acetate 8件: 13, 35, 46, 49, 50, 51, 60, 107 💬 💬
323 Chemical carcinogenesis - receptor activation 💬
 1件: PGR 💬 Nomegestrol 💬 Nomegestrol 1件: 13 💬 💬
324 Chemical carcinogenesis - receptor activation 💬
 1件: PGR 💬 Nomegestrol acetate 💬 Nomegestrol acetate 1件: 13 💬 💬
325 Chemical carcinogenesis - receptor activation 💬
 1件: PGR 💬 Norethindrone 💬 Norethisterone 4件: 13, 46, 49, 299 💬 💬
326 Chemical carcinogenesis - receptor activation 💬
 3件: RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene 2件: 13,