Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Leucine [1] Leucine[2] L-leucine; Leucine; --[6] 6, 19, 65, 283, 284, 299
2 Cholesterol [1] Cholesterol[1] Cholesterol; --[6] 8, 19, 90, 160, 222, 310
3 Gelatin [1] Gelatin[3] Gelatin; Gelatine; Sulfur Colloid; --[7] 19, 28, 62, 78, 97, 269, 299
4 Methotrexate [1] Methotrexate[6] Methotrexat; Methotrexate; METHOTREXATE SODIUM; Metoject; METOTREXATO; Méthotrexate; [2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
5 Angiotensin II [1] Angiotensin II[2] Angiotensin; Angiotensin II; [2] AGTR1,
AGTR2 💬		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 17, 19, 46, 66, 86, 222, 224
6 Cyclosporine [1] Cyclosporine[10] CICLOSPORIN; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; RESTASIS; [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
7 Cholecalciferol [1] Cholecalciferol[5] Cholecalciferol; Colecalciferol; Multivitamin; Vitamin D; Vitamin D3; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[24] 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
8 Acetylcysteine [1] Acetylcysteine[3] ACETYLCYSTEINE; Mucomyst; N-acetylcysteine; --[21] 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
9 Amoxicillin [1] Amoxicillin[4] Amoxicilina; AMOXICILLIN; Amoxycillin; Augmentin; --[9] 6, 19, 46, 63, 84, 96, 97, 222, 299
10 Azathioprine [1] Azathioprine[3] AZATHIOPRINE; Azatioprina; Imuran; --[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
11 Busulfan [1] Busulfan[3] Busilvex; Busulfan; BUSULFANO; --[13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326
12 Cyclophosphamide [1] Cyclophosphamide[6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan; --[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331
13 Gabapentin [1] Gabapentin[4] GABAPENTIN; GABAPENTINA; Gabapentine; NEURONTIN; [5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[5] 6, 13, 19, 70, 298
14 Hydroxyurea [1] Hydroxyurea[1] Hydroxyurea; [1] RRM2 💬[7] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[8] 3, 13, 19, 20, 65, 85, 86, 284
15 Lisinopril [1] Lisinopril[2] Lisinopril; ZESTRIL; [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222
16 Melphalan [1] Melphalan[3] Alkeran; Melphalan; Melphalan Hydrochloride; --[15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299
17 Methylprednisolone [1] Methylprednisolone[4] Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296
18 Prednisone [1] Prednisone[3] PREDNISONA; Prednisone; RAYOS; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331
19 Pyrimethamine [1] Pyrimethamine[2] Daraprim; Pyrimethamine; --[12] 2, 4, 6, 13, 19, 46, 51, 63, 65, 96, 97, 265
20 Thiotepa [1] Thiotepa[1] Thiotepa; --[12] 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285
21 Mycophenolate mofetil [1] Mycophenolate mofetil[3] CellCept; Mycophenolate Mofetil; Mycophenolate mofetil TEVA; [2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
22 Sirolimus [1] Sirolimus[3] Rapamune; Rapamycin; SIROLIMUS; [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[40] 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331
23 Paricalcitol [1] Paricalcitol[1] Paricalcitol; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[5] 19, 66, 218, 238, 298
24 Calcium carbonate [1] Calcium carbonate[3] Calcio carbonato; Calcium; Calcium carbonate; --[9] 13, 19, 46, 53, 75, 96, 235, 274, 299
25 Iohexol [1] Iohexol[2] Iohexol; OMNIPAQUE; --[3] 19, 67, 222
26 Angiotensin II [1] Angiotensin II[2] Angiotensin; Angiotensin II; [2] AGTR1,
AGTR2 💬		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 17, 19, 46, 66, 86, 222, 224
27 Lysine [1] Lysine[1] Lysine; --[5] 13, 19, 97, 228, 299
28 Betadex [1] Betadex[1] Beta-cyclodextrin; --[1] 19
29 Adalimumab [1] Adalimumab[7] ADALIMUMAB; AMGEVITA; Cyltezo; Hulio; Humira; Hyrimoz; Imraldi; [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271
30 Agalsidase alfa [1] Agalsidase alfa[5] AGALSIDASE ALFA; Agalsidase Alpha; Alpha-galactosidase A; Recombinant alpha-galactosidase A; REPLAGAL; [1] GLA 💬[6] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬[1] 19
31 Alemtuzumab [1] Alemtuzumab[4] Alemtuzumab; Campath; Lemtrada; MABCAMPATH; [1] CD52 💬-[22] 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326
32 Alglucerase [1] Alglucerase[1] Ceredase; [1] GBA1 💬[4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19
33 Rituximab [1] Rituximab[6] MABTHERA; Rituxan; Rituximab; Rixathon; Ruxience; Truxima; [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
34 Imiglucerase [1] Imiglucerase[3] CEREZYME; IMIGLUCERASA; IMIGLUCERASE; [1] GBA1 💬[4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19
35 Abatacept [1] Abatacept[2] Abatacept; Orencia; [2] CD80,
CD86 💬		[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
36 Agalsidase beta [1] Agalsidase beta[2] AGALSIDASE BETA; FABRAZYME; [1] GLA 💬[6] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬[1] 19
37 Lenograstim [1] Lenograstim[2] G-CSF; LENOGRASTIM; [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[7] 2, 13, 16, 18, 19, 57, 65
38 Lactase [1] Tilactase[1] Beta-Galactosidase; --[1] 19
39 Clofarabine [1] Clofarabine[1] Clofarabine; [3] POLA1,
POLA2,
RRM1 💬		[7] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[5] 19, 20, 60, 234, 326
40 Cysteamine [1] Cysteamine[8] 2-aminoethanethiol; Beta-Mercaptoethylamine; CYSTADROPS; Cystagon; Cysteamine; Mercaptamina; Mercaptamine; PROCYSBI; --[4] 8, 19, 21, 299
41 Quinapril [1] Quinapril[1] Accuretic; [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 19
42 Idursulfase [1] Idursulfase[4] Elaprase; Iduronate 2-sulfatase; IDURSULFASA; IDURSULFASE; [1] IDS 💬[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[1] 19
43 Laronidase [1] Laronidase[2] Aldurazyme; LARONIDASE; [1] IDUA 💬[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[2] 19, 256
44 Miglustat [1] Miglustat[2] Miglustat; Zavesca; [1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[3] 19, 256, 299
45 Mycophenolic acid [1] Mycophenolic acid[5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; MYCOPHENOLIC ACID; Myfortic; [2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
46 Galsulfase [1] Galsulfase[2] GALSULFASE; Naglazyme; [1] ARSB 💬[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[1] 19
47 Donkey glue [1] Gelatin[3] Gelatin; Gelatine; Sulfur Colloid; --[7] 19, 28, 62, 78, 97, 269, 299
48 Alendronic acid [1] Alendronic acid[3] Alendronate; Alendronate sodium; ALENDRONIC ACID; [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[7] 19, 41, 46, 50, 271, 274, 299
49 Gamolenic acid [1] Gamolenic acid[2] Gamma-Linolenic acid; Linolenic acid; --[3] 13, 19, 46
50 Treosulfan [1] Treosulfan[2] OVASTAT; Treosulfan; --[6] 13, 19, 62, 65, 283, 286
51 Ambroxol [1] Ambroxol[1] Ambroxol; --[2] 6, 19
52 Amoxicillin [1] Amoxicillin[4] Amoxicilina; AMOXICILLIN; Amoxycillin; Augmentin; --[9] 6, 19, 46, 63, 84, 96, 97, 222, 299
53 Betaine [1] Betaine[2] Betaine; Cystadane; --[3] 19, 201, 337
54 Cyclophosphamide [1] Cyclophosphamide[6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan; --[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331
55 Enalapril [1] Enalapril[2] Enalapril; Enalapril Maleate; [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[6] 19, 46, 66, 113, 210, 222
56 Fludarabine [1] Fludarabine[4] FLUDARA; Fludarabina; FLudarabine; Fludarabine phosphate; [1] RRM1 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
57 Folinic acid [1] Leucovorin[2] Folinic acid; Leucovorin; --[4] 19, 46, 107, 320
58 Folinic acid calcium salt pentahydrate [1] Leucovorin[2] Folinic acid; Leucovorin; --[4] 19, 46, 107, 320
59 Levothyroxine [1] Levothyroxine[2] Levothyroxine; Thyroxine; [2] THRA,
THRB 💬		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[5] 19, 49, 78, 80, 222
60 Lisinopril [1] Lisinopril[2] Lisinopril; Zestril; [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222
61 Losartan [1] Losartan[3] Cozaar; Losartan; LOSARTAN POTASSIUM; [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
62 Warfarin [1] Warfarin[2] Warfarin; Warfarin Sodium; [2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[11] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91
63 Dapagliflozin [1] Dapagliflozin[2] Dapagliflozin; Forxiga; [1] SLC5A2 💬-[7] 19, 49, 66, 67, 86, 88, 222
64 Plerixafor [1] Plerixafor[2] Mozobil; Plerixafor; [1] CXCR4 💬[14] Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬[5] 19, 20, 65, 285, 299
65 Velaglucerase alfa [1] Velaglucerase alfa[3] GA-GCB; VELAGLUCERASE ALFA; VPRIV; [1] GBA1 💬[4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19
66 Ataluren [1] Ataluren[2] Ataluren; Translarna; --[6] 19, 113, 140, 246, 299, 329
67 Afegostat [1] Afegostat[1] Afegostat; --[1] 19
68 Taliglucerase alfa [1] Taliglucerase alfa[3] Elelyso; PrGCD; TALIGLUCERASE ALFA; [1] GBA1 💬[4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19
69 Eliglustat [1] Eliglustat[2] Cerdelga; Eliglustat; [1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[1] 19
70 Elosulfase alfa [1] Elosulfase alfa[3] Elosulfase alfa; Recombinant human N-acetylgalactosamine-6-sulfatase; RhGALNS; [1] GALNS 💬[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[1] 19
71 Migalastat [1] Migalastat[3] 1-Deoxygalactonojirimycin; Galafold; MIGALASTAT; --[1] 19
72 Sofosbuvir [1] Sofosbuvir[1] Sofosbuvir; --[1] 19
73 Sebelipase alfa [1] Sebelipase alfa[4] KANUMA; SBC-102; Sebelipasa Alfa; Sebelipase Alfa; [1] LIPA 💬[3] Cholesterol metabolism, Lysosome, Steroid biosynthesis 💬[1] 19
74 Ledipasvir [1] Ledipasvir[1] Ledipasvir; --[1] 19
75 Calcium carbonate [1] Calcium carbonate[3] Calcio carbonato; Calcium; Calcium carbonate; --[9] 13, 19, 46, 53, 75, 96, 235, 274, 299
76 Cerliponase alfa [1] Cerliponase alfa[2] Brineura; Cerliponase Alfa; [1] TPP1 💬[1] Lysosome 💬[1] 19
77 Olipudase alfa [1] Olipudase alfa[1] OLIPUDASE ALFA; [1] SMPD1 💬[5] Lysosome, Metabolic pathways, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬[1] 19
78 Vestronidase alfa [1] Vestronidase alfa[3] Mepsevii; Recombinant human beta-glucuronidase; Vestronidase alfa; [1] GUSB 💬[8] Ascorbate and aldarate metabolism, Biosynthesis of cofactors, Drug metabolism - other enzymes, Glycosaminoglycan degradation, Lysosome, Metabolic pathways, Pentose and glucuronate interconversions, Porphyrin metabolism 💬[1] 19
79 Velmanase alfa [1] Velmanase alfa[3] LAMAZYM; RhLAMAN; VELMANASE ALFA; [1] MAN2B1 💬[2] Lysosome, Other glycan degradation 💬[1] 19
80 Idursulfase beta [1] Idursulfase beta[3] Hunterase; Iduronate 2-sulfatase; Idursulfase beta; [1] IDS 💬[3] Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬[1] 19
81 Rimiducid [1] Rimiducid[1] Rimiducid; [1] CASP9 💬[35] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬[6] 19, 60, 65, 284, 285, 326
82 Arimoclomol [1] Arimoclomol[1] ARIMOCLOMOL; --[3] 2, 15, 19
83 Lucerastat [1] Lucerastat[1] Lucerastat; [1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[1] 19
84 Venglustat [1] Venglustat[2] GENZ-682452; Venglustat; [1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[3] 6, 19, 67
85 Genistein [1] Genistein[1] GENISTEIN; --[2] 19, 299
86 Pegunigalsidase alfa [1] Pegunigalsidase alfa[1] PEGUNIGALSIDASE ALFA; --[1] 19
87 Pabinafusp alfa [1] Pabinafusp alfa[1] Pabinafusp alfa; [2] IDS,
TFRC 💬		[8] Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome, Metabolic pathways, Phagosome 💬[1] 19