Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CDK4 [2] Tight junction, Viral carcinogenesis D10688 Abemaciclib [1] 34
2 CFTR [2] Tight junction, Vibrio cholerae infection D09916 Ivacaftor [1] 299
3 CFTR [2] Tight junction, Vibrio cholerae infection D10134 Lumacaftor [1] 299
4 CFTR [2] Tight junction, Vibrio cholerae infection D11041 Tezacaftor [1] 299
5 CFTR [2] Tight junction, Vibrio cholerae infection D11423 Deutivacaftor [1] 299
6 CFTR [2] Tight junction, Vibrio cholerae infection D11507 Elexacaftor [1] 299
7 CFTR [2] Tight junction, Vibrio cholerae infection D11724 Galicaftor [1] 299
8 ERBB2 [1] Tight junction D08108 Lapatinib [3] 34, 74, 75
9 ERBB2 [1] Tight junction D08950 Neratinib [1] 34
10 ERBB2 [1] Tight junction D11772 Tesevatinib [1] 67
11 MAP3K5 [2] Tight junction, TNF signaling pathway D10988 Selonsertib [1] 86
12 PRKAA1 [1] Tight junction D04966 Metformin [25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
13 PRKAA2 [1] Tight junction D04966 Metformin [25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
14 PRKCE [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D09671 Sotrastaurin [1] 97
15 ROCK1 [3] Vascular smooth muscle contraction, Tight junction, Yersinia infection D07941 Fasudil [4] 2, 5, 7, 51
16 SRC [5] VEGF signaling pathway, Tight junction, Yersinia infection, Tuberculosis, Viral carcinogenesis D03252 Bosutinib [2] 2, 67
17 SRC [5] VEGF signaling pathway, Tight junction, Yersinia infection, Tuberculosis, Viral carcinogenesis D03658 Dasatinib [2] 51, 85
18 SRC [5] VEGF signaling pathway, Tight junction, Yersinia infection, Tuberculosis, Viral carcinogenesis D06414 Dasatinib [2] 51, 85
19 SRC [5] VEGF signaling pathway, Tight junction, Yersinia infection, Tuberculosis, Viral carcinogenesis D09664 Saracatinib [3] 6, 89, 272
20 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00349 Isradipine [1] 6
21 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00437 Nifedipine [2] 50, 81
22 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
23 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D01173 Cilnidipine [1] 67
24 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D01908 Nilvadipine [1] 90
25 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D02356 Verapamil [4] 58, 96, 140, 167
26 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D07450 Amlodipine [4] 13, 51, 67, 298
27 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D07845 Diltiazem [3] 51, 58, 86
28 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D08270 Nicardipine [2] 70, 86
29 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D08340 Perhexiline [2] 58, 272
30 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D08441 Propiverine [1] 226
31 ROCK2 [4] Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Yersinia infection D07941 Fasudil [4] 2, 5, 7, 51
32 ROCK2 [4] Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Yersinia infection D11815 Belumosudil [2] 51, 85