Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 MAPK14 [17] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
2 MAPK14 [17] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
3 EDNRB [1] Relaxin signaling pathway D01227 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
4 EDNRB [1] Relaxin signaling pathway D07538 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
5 EDNRB [1] Relaxin signaling pathway D10135 Macitentan [5] 51, 85, 86, 88, 210
6 EGFR [2] Relaxin signaling pathway, Shigellosis D01977 Gefitinib [1] 75
7 EGFR [2] Relaxin signaling pathway, Shigellosis D03455 Cetuximab [2] 51, 86
8 EGFR [2] Relaxin signaling pathway, Shigellosis D07907 Erlotinib [1] 94
9 EGFR [2] Relaxin signaling pathway, Shigellosis D08108 Lapatinib [3] 34, 74, 75
10 EGFR [2] Relaxin signaling pathway, Shigellosis D08950 Neratinib [1] 34
11 EGFR [2] Relaxin signaling pathway, Shigellosis D11251 Icotinib [1] 34
12 EGFR [2] Relaxin signaling pathway, Shigellosis D11772 Tesevatinib [1] 67
13 MMP13 [1] Relaxin signaling pathway D08859 Apratastat [1] 46
14 NFKB1 [16] Sphingolipid signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Small cell lung cancer D01146 Iguratimod [5] 46, 51, 53, 271, 300
15 PIK3CA [16] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11011 Alpelisib [1] 138
16 PIK3CA [16] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib [2] 53, 65
17 PIK3CB [16] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib [2] 53, 65
18 PIK3CD [16] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib [2] 53, 65
19 PIK3CD [16] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11437 Parsaclisib [3] 35, 53, 61
20 MAPK11 [17] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
21 MAPK11 [17] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
22 MAPK13 [17] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
23 MAPK13 [17] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
24 MAP2K1 [14] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib [1] 34
25 MAP2K1 [14] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10175 Trametinib [4] 2, 34, 279, 280
26 MAP2K1 [14] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib [1] 280
27 MAP2K1 [14] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib [1] 34
28 MAP2K1 [14] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D11675 Mirdametinib [1] 34
29 MAP2K2 [12] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib [1] 34
30 MAP2K2 [12] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10175 Trametinib [4] 2, 34, 279, 280
31 MAP2K2 [12] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib [1] 280
32 MAP2K2 [12] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib [1] 34
33 MAP2K2 [12] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D11675 Mirdametinib [1] 34
34 RAF1 [11] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Renal cell carcinoma D08524 Sorafenib [2] 34, 86
35 RELA [16] Sphingolipid signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Small cell lung cancer D12181 Edasalonexent [1] 113
36 MAPK12 [17] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
37 MAPK12 [17] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
38 SRC [8] VEGF signaling pathway, Tight junction, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D03252 Bosutinib [2] 2, 67
39 SRC [8] VEGF signaling pathway, Tight junction, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D03658 Dasatinib [2] 51, 85
40 SRC [8] VEGF signaling pathway, Tight junction, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D06414 Dasatinib [2] 51, 85
41 SRC [8] VEGF signaling pathway, Tight junction, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D09664 Saracatinib [3] 6, 89, 272
42 TGFB1 [7] TGF-beta signaling pathway, Th17 cell differentiation, Relaxin signaling pathway, Toxoplasmosis, Tuberculosis, Renal cell carcinoma, Rheumatoid arthritis D09620 Fresolimumab [3] 51, 85, 222
43 VEGFA [4] VEGF signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis D05697 Ranibizumab [4] 34, 166, 227, 301
44 VEGFA [4] VEGF signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis D06409 Bevacizumab [6] 13, 34, 85, 87, 227, 280
45 VEGFA [4] VEGF signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis D09574 Aflibercept [2] 90, 166
46 VEGFB [1] Relaxin signaling pathway D09574 Aflibercept [2] 90, 166