Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adherens junction 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
2 Adrenergic signaling in cardiomyocytes 💬
 [5] CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
3 Alcoholism 💬
 [1] DRD2 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
4 Alcoholism 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
5 Alcoholism 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
6 Aldosterone synthesis and secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
7 Aldosterone-regulated sodium reabsorption 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
8 Alzheimer disease 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
9 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 D11383 💬 Blarcamesine [1] 156 💬
10 Alzheimer disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
11 Alzheimer disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
12 Alzheimer disease 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
13 Amphetamine addiction 💬
 [6] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
14 Amphetamine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
15 Amphetamine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
16 AMPK signaling pathway 💬
 [1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
17 AMPK signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
18 Amyotrophic lateral sclerosis 💬
 [2] GRIA1, GRIA2 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
19 Amyotrophic lateral sclerosis 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
20 Amyotrophic lateral sclerosis 💬
 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
21 Amyotrophic lateral sclerosis 💬
 [1] SIGMAR1 💬 D11383 💬 Blarcamesine [1] 156 💬
22 Arrhythmogenic right ventricular cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
23 Bile secretion 💬
 [1] CA2 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
24 Bile secretion 💬
 [1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
25 Calcium signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
26 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 D11383 💬 Blarcamesine [1] 156 💬
27 Calcium signaling pathway 💬
 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
28 Calcium signaling pathway 💬
 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
29 Calcium signaling pathway 💬
 [1] HTR2A 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
30 cAMP signaling pathway 💬
 [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
31 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D11383 💬 Blarcamesine [1] 156 💬
32 cAMP signaling pathway 💬
 [1] DRD2 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
33 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
34 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
35 Carbohydrate digestion and absorption 💬
 [1] CACNA1D 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
36 Cardiac muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
37 Cellular senescence 💬
 [1] CACNA1D 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
38 cGMP-PKG signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
39 cGMP-PKG signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
40 Chemical carcinogenesis - receptor activation 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
41 Cholinergic synapse 💬
 [1] ACHE 💬 D07869 💬 Donepezil [9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
42 Cholinergic synapse 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
43 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D11383 💬 Blarcamesine [1] 156 💬
44 Circadian entrainment 💬
 [6] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
45 Circadian entrainment 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
46 Circadian entrainment 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
47 Cocaine addiction 💬
 [1] DRD2 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
48 Cocaine addiction 💬
 [1] GRIA2 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
49 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
50 Cocaine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
51 Collecting duct acid secretion 💬
 [1] CA2 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
52 Cortisol synthesis and secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
53 Cushing syndrome 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
54 Diabetic cardiomyopathy 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
55 Dilated cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
56 Dopaminergic synapse 💬
 [7] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, SCN1A 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
57 Dopaminergic synapse 💬
 [1] DRD2 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
58 Dopaminergic synapse 💬
 [2] GRIN2A, GRIN2B 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
59 Dopaminergic synapse 💬
 [2] GRIN2A, GRIN2B 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
60 FoxO signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
61 FoxO signaling pathway 💬
 [1] S1PR1 💬 D10001 💬 Fingolimod [3] 13, 14, 156 💬
62 GABAergic synapse 💬
 [20] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
63 Gap junction 💬
 [2] DRD2, HTR2A 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
64 Gastric acid secretion 💬
 [1] CA2 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
65 Gastric acid secretion 💬
 [1] CHRM3 💬 D11383 💬 Blarcamesine [1] 156 💬
66 Glutamatergic synapse 💬
 [11] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
67 Glutamatergic synapse 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
68 Glutamatergic synapse 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
69 Glycerophospholipid metabolism 💬
 [1] ACHE 💬 D07869 💬 Donepezil [9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
70 GnRH secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
71 GnRH signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
72 Growth hormone synthesis, secretion and action 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
73 HIF-1 signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
74 Huntington disease 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
75 Huntington disease 💬
 [2] GRIN1, GRIN2B 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
76 Huntington disease 💬
 [2] GRIN1, GRIN2B 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
77 Hypertrophic cardiomyopathy 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
78 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2A 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
79 Insulin resistance 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
80 Insulin secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
81 Insulin secretion 💬
 [1] CHRM3 💬 D11383 💬 Blarcamesine [1] 156 💬
82 Insulin signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
83 Long-term depression 💬
 [3] GRIA1, GRIA2, GRIA3 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
84 Long-term potentiation 💬
 [3] CACNA1C, GRIA1, GRIA2 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
85 Long-term potentiation 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
86 Long-term potentiation 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
87 Longevity regulating pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
88 Longevity regulating pathway - multiple species 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
89 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
90 MAPK signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
91 Metabolic pathways 💬
 [2] CA2, CA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
92 Metabolic pathways 💬
 [1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
93 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
94 mTOR signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
95 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D11383 💬 Blarcamesine [1] 156 💬
96 Neuroactive ligand-receptor interaction 💬
 [2] CNR1, CNR2 💬 D10915 💬 Cannabidiol [20]  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
97 Neuroactive ligand-receptor interaction 💬
 [2] DRD2, HTR2A 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
98 Neuroactive ligand-receptor interaction 💬
 [25] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
99 Neuroactive ligand-receptor interaction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
100 Neuroactive ligand-receptor interaction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
101 Neuroactive ligand-receptor interaction 💬
 [1] S1PR1 💬 D10001 💬 Fingolimod [3] 13, 14, 156 💬
102 Nicotine addiction 💬
 [20] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
103 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
104 Nicotine addiction 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
105 Nitrogen metabolism 💬
 [2] CA2, CA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
106 Non-alcoholic fatty liver disease 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
107 Ovarian steroidogenesis 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
108 Oxytocin signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
109 Pancreatic secretion 💬
 [1] CA2 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
110 Pancreatic secretion 💬
 [1] CHRM3 💬 D11383 💬 Blarcamesine [1] 156 💬
111 Parkinson disease 💬
 [1] DRD2 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
112 Pathways of neurodegeneration - multiple diseases 💬
 [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
113 Pathways of neurodegeneration - multiple diseases 💬
 [4] CHRM1, CHRM3, CHRM5, SIGMAR1 💬 D11383 💬 Blarcamesine [1] 156 💬
114 Pathways of neurodegeneration - multiple diseases 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
115 Pathways of neurodegeneration - multiple diseases 💬
 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
116 Phospholipase D signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
117 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D11383 💬 Blarcamesine [1] 156 💬
118 PI3K-Akt signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
119 Prion disease 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
120 Prion disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
121 Prion disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
122 Proximal tubule bicarbonate reclamation 💬
 [2] CA2, CA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
123 Rap1 signaling pathway 💬
 [1] CNR1 💬 D10915 💬 Cannabidiol [20]  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
124 Rap1 signaling pathway 💬
 [1] DRD2 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
125 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
126 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
127 Rap1 signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
128 Ras signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
129 Ras signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
130 Ras signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
131 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D11383 💬 Blarcamesine [1] 156 💬
132 Regulation of lipolysis in adipocytes 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
133 Renin secretion 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
134 Retrograde endocannabinoid signaling 💬
 [24] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
135 Retrograde endocannabinoid signaling 💬
 [1] CNR1 💬 D10915 💬 Cannabidiol [20]  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
136 Salivary secretion 💬
 [1] CHRM3 💬 D11383 💬 Blarcamesine [1] 156 💬
137 Serotonergic synapse 💬
 [7] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRB1, GABRB2, GABRB3 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
138 Serotonergic synapse 💬
 [1] HTR2A 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
139 Serotonergic synapse 💬
 [1] SLC6A4 💬 D07791 💬 Desipramine [2] 120, 156 💬
140 Sphingolipid signaling pathway 💬
 [1] S1PR1 💬 D10001 💬 Fingolimod [3] 13, 14, 156 💬
141 Spinocerebellar ataxia 💬
 [3] GRIA1, GRIA2, GRIA3 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
142 Spinocerebellar ataxia 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
143 Spinocerebellar ataxia 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
144 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 D07791 💬 Desipramine [2] 120, 156 💬
145 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
146 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
147 Taste transduction 💬
 [10] CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
148 Taste transduction 💬
 [1] CHRM3 💬 D11383 💬 Blarcamesine [1] 156 💬
149 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
150 Thermogenesis 💬
 [1] CNR1 💬 D10915 💬 Cannabidiol [20]  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
151 Tight junction 💬
 [1] CACNA1D 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
152 Transcriptional misregulation in cancer 💬
 [1] GRIA3 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
153 Type II diabetes mellitus 💬
 [2] CACNA1C, CACNA1D 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
154 Type II diabetes mellitus 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
155 Vascular smooth muscle contraction 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬

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