Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
2 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
3 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
4 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D02716 D02716 💬 |
Pregabalin | 013 [5] 13, 36, 46, 70, 298 💬 |
5 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
SCN5A [1] SCN5A 💬 |
D07552 D07552 💬 |
Bupivacaine | 046 [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 |
6 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
7 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
8 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
9 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
10 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
11 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
12 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
13 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
14 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
15 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
16 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
17 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
18 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
19 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
20 | Antigen processing and presentation 💬 Related to 4 target genes, 15 drugs (DrugBank) and 52 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
21 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
22 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
23 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 43 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
24 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
25 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
26 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D02716 D02716 💬 |
Pregabalin | 013 [5] 13, 36, 46, 70, 298 💬 |
27 | Asthma 💬 Related to 8 target genes, 22 drugs (DrugBank) and 55 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
28 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
29 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
30 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
31 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
32 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
CCKBR [1] CCKBR 💬 |
D01818 D01818 💬 |
Proglumide | 298 [1] 298 💬 |
33 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
34 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
35 | Carbohydrate digestion and absorption 💬 Related to 14 target genes, 19 drugs (DrugBank) and 30 diseases in DDrare |
AMY2A [3] AMY2A, AMY2B, MGAM 💬 |
D00216 D00216 💬 |
Acarbose | 298 [1] 298 💬 |
36 | Carbohydrate digestion and absorption 💬 Related to 14 target genes, 19 drugs (DrugBank) and 30 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
37 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
38 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
39 | Cardiac muscle contraction 💬 Related to 13 target genes, 17 drugs (DrugBank) and 26 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D02716 D02716 💬 |
Pregabalin | 013 [5] 13, 36, 46, 70, 298 💬 |
40 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
41 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
42 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D05312 D05312 💬 |
Oxycodone | 006 [5] 6 , 13, 70, 226, 298 💬 |
43 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
44 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 40 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
45 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
46 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
47 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
VDR [1] VDR 💬 |
D00930 D00930 💬 |
Paricalcitol | 019 [5] 19, 66, 218, 238, 298 💬 |
48 | Chemokine signaling pathway 💬 Related to 22 target genes, 29 drugs (DrugBank) and 51 diseases in DDrare |
CXCR1 [2] CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 [2] 298, 299 💬 |
49 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
50 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
51 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
52 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 |
53 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
54 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
55 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
56 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
CXCR1 [2] CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 [2] 298, 299 💬 |
57 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
58 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
59 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
60 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
61 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D02716 D02716 💬 |
Pregabalin | 013 [5] 13, 36, 46, 70, 298 💬 |
62 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
63 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
64 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
SCN1A [1] SCN1A 💬 |
D07552 D07552 💬 |
Bupivacaine | 046 [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 |
65 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
66 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR [1] VDR 💬 |
D00930 D00930 💬 |
Paricalcitol | 019 [5] 19, 66, 218, 238, 298 💬 |
67 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
CXCR1 [2] CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 [2] 298, 299 💬 |
68 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
CXCR1 [2] CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 [2] 298, 299 💬 |
69 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
70 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D05312 D05312 💬 |
Oxycodone | 006 [5] 6 , 13, 70, 226, 298 💬 |
71 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
72 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
73 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
74 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
75 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
76 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
SLC6A1 [1] SLC6A1 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
77 | Galactose metabolism 💬 Related to 4 target genes, 7 drugs (DrugBank) and 3 diseases in DDrare |
GAA [3] GAA, GANC, MGAM 💬 |
D00216 D00216 💬 |
Acarbose | 298 [1] 298 💬 |
78 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
79 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 |
80 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CCKBR [1] CCKBR 💬 |
D01818 D01818 💬 |
Proglumide | 298 [1] 298 💬 |
81 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
82 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
83 | GnRH signaling pathway 💬 Related to 16 target genes, 36 drugs (DrugBank) and 37 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
84 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
85 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
86 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
87 | Hepatitis B 💬 Related to 41 target genes, 54 drugs (DrugBank) and 73 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
88 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
89 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
90 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
CXCR2 [1] CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 [2] 298, 299 💬 |
91 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
92 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
93 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
94 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
95 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
96 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
97 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
98 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
99 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
100 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D02716 D02716 💬 |
Pregabalin | 013 [5] 13, 36, 46, 70, 298 💬 |
101 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
102 | IL-17 signaling pathway 💬 Related to 20 target genes, 60 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
103 | IL-17 signaling pathway 💬 Related to 20 target genes, 60 drugs (DrugBank) and 83 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
104 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
105 | Inflammatory mediator regulation of TRP channels 💬 Related to 23 target genes, 43 drugs (DrugBank) and 59 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
106 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
107 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
108 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
109 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
110 | Legionellosis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
111 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
112 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
113 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
114 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
115 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
116 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
117 | Lysosome 💬 Related to 14 target genes, 24 drugs (DrugBank) and 6 diseases in DDrare |
GAA [1] GAA 💬 |
D00216 D00216 💬 |
Acarbose | 298 [1] 298 💬 |
118 | Malaria 💬 Related to 15 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
119 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
120 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
121 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D02716 D02716 💬 |
Pregabalin | 013 [5] 13, 36, 46, 70, 298 💬 |
122 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
123 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
124 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
AMY2A [5] AMY2A, AMY2B, GAA, GANC, MGAM 💬 |
D00216 D00216 💬 |
Acarbose | 298 [1] 298 💬 |
125 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
126 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 |
127 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
128 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
129 | MicroRNAs in cancer 💬 Related to 31 target genes, 65 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
130 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 41 diseases in DDrare |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
131 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 41 diseases in DDrare |
VDR [1] VDR 💬 |
D00930 D00930 💬 |
Paricalcitol | 019 [5] 19, 66, 218, 238, 298 💬 |
132 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
133 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
134 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D05312 D05312 💬 |
Oxycodone | 006 [5] 6 , 13, 70, 226, 298 💬 |
135 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
136 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
137 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
138 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
CCKBR [1] CCKBR 💬 |
D01818 D01818 💬 |
Proglumide | 298 [1] 298 💬 |
139 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
CNR1 [2] CNR1, CNR2 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬 |
140 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
141 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
142 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 [1] NR3C1 💬 |
D00385 D00385 💬 |
Triamcinolone | 035 [11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬 |
143 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬 |
D05312 D05312 💬 |
Oxycodone | 006 [5] 6 , 13, 70, 226, 298 💬 |
144 | Neurotrophin signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 32 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
145 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
146 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
147 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
148 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
149 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
150 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
151 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
152 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
153 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
154 | Ovarian steroidogenesis 💬 Related to 7 target genes, 36 drugs (DrugBank) and 52 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
155 | Oxidative phosphorylation 💬 Related to 2 target genes, 7 drugs (DrugBank) and 25 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 |
156 | Oxidative phosphorylation 💬 Related to 2 target genes, 7 drugs (DrugBank) and 25 diseases in DDrare |
ATP4A [2] ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 |
157 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
158 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
159 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
D02716 D02716 💬 |
Pregabalin | 013 [5] 13, 36, 46, 70, 298 💬 |
160 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
161 | Pancreatic secretion 💬 Related to 13 target genes, 35 drugs (DrugBank) and 36 diseases in DDrare |
AMY2A [2] AMY2A, AMY2B 💬 |
D00216 D00216 💬 |
Acarbose | 298 [1] 298 💬 |
162 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
163 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
VDR [1] VDR 💬 |
D00930 D00930 💬 |
Paricalcitol | 019 [5] 19, 66, 218, 238, 298 💬 |
164 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
165 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
166 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
167 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
168 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
169 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
170 | Pertussis 💬 Related to 18 target genes, 38 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
171 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
CXCR1 [2] CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 [2] 298, 299 💬 |
172 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
173 | Platelet activation 💬 Related to 22 target genes, 51 drugs (DrugBank) and 56 diseases in DDrare |
PTGS1 [1] PTGS1 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
174 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
175 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
176 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
177 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
178 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬 |
179 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
180 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
181 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
182 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
183 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
184 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬 |
185 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
186 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
187 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
188 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
189 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
190 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
AMY2A [2] AMY2A, AMY2B 💬 |
D00216 D00216 💬 |
Acarbose | 298 [1] 298 💬 |
191 | Salmonella infection 💬 Related to 27 target genes, 40 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
192 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
193 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
194 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬 |
D00550 D00550 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
195 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
196 | Shigellosis 💬 Related to 23 target genes, 41 drugs (DrugBank) and 86 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
197 | Small cell lung cancer 💬 Related to 14 target genes, 39 drugs (DrugBank) and 59 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
198 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
OPRD1 [1] OPRD1 💬 |
D05312 D05312 💬 |
Oxycodone | 006 [5] 6 , 13, 70, 226, 298 💬 |
199 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
200 | Starch and sucrose metabolism 💬 Related to 5 target genes, 5 drugs (DrugBank) and 2 diseases in DDrare |
AMY2A [5] AMY2A, AMY2B, GAA, GANC, MGAM 💬 |
D00216 D00216 💬 |
Acarbose | 298 [1] 298 💬 |
201 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A1 [1] SLC6A1 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
202 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
203 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
204 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1C [1] CACNA1C 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
205 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
206 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00550 D00550 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
207 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
D07552 D07552 💬 |
Bupivacaine | 046 [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 |
208 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
SCN3A [2] SCN3A, SCN9A 💬 |
D07299 D07299 💬 |
Lacosamide | 002 [4] 2 , 46, 149, 298 💬 |
209 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
HMGCR [1] HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
210 | TGF-beta signaling pathway 💬 Related to 10 target genes, 20 drugs (DrugBank) and 55 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
211 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬 |
212 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
213 | Thyroid cancer 💬 Related to 8 target genes, 16 drugs (DrugBank) and 28 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
214 | Tight junction 💬 Related to 11 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
CACNA1D [1] CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
215 | TNF signaling pathway 💬 Related to 18 target genes, 56 drugs (DrugBank) and 84 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
216 | TNF signaling pathway 💬 Related to 18 target genes, 56 drugs (DrugBank) and 84 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
217 | Toll-like receptor signaling pathway 💬 Related to 36 target genes, 46 drugs (DrugBank) and 65 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
218 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
219 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
220 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
221 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
222 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
VDR [1] VDR 💬 |
D00930 D00930 💬 |
Paricalcitol | 019 [5] 19, 66, 218, 238, 298 💬 |
223 | Type I diabetes mellitus 💬 Related to 11 target genes, 22 drugs (DrugBank) and 68 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
224 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
CACNA1C [2] CACNA1C, CACNA1D 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
225 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
226 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
227 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
228 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CXCR1 [2] CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 [2] 298, 299 💬 |
229 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
230 | Yersinia infection 💬 Related to 22 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |