Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 NF-kappa B signaling pathway 💬
 [1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
2 NF-kappa B signaling pathway 💬
 [1] BTK 💬 D10893 💬 Acalabrutinib [2] 46, 61 💬
3 NF-kappa B signaling pathway 💬
 [1] BTK 💬 D11478 💬 Branebrutinib [3] 46, 49, 53 💬
4 NF-kappa B signaling pathway 💬
 [1] BTK 💬 D12467 💬 Evobrutinib [3] 13, 46, 49 💬
5 NF-kappa B signaling pathway 💬
 [1] BTK 💬 D11457 💬 Fenebrutinib [1] 13 💬
6 NF-kappa B signaling pathway 💬
 [1] BTK 💬 D10223 💬 Ibrutinib [3] 28, 60, 61 💬
7 NF-kappa B signaling pathway 💬
 [1] BTK 💬 D12160 💬 Orelabrutinib [4] 13, 49, 61, 63 💬
8 NF-kappa B signaling pathway 💬
 [1] BTK 💬 D12285 💬 Remibrutinib [2] 13, 53 💬
9 NF-kappa B signaling pathway 💬
 [1] BTK 💬 D11422 💬 Zanubrutinib [5] 13, 63, 222, 300, 331 💬
10 NF-kappa B signaling pathway 💬
 [1] CD40 💬 D11357 💬 Bleselumab [1] 222 💬
11 NF-kappa B signaling pathway 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
12 NF-kappa B signaling pathway 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
13 NF-kappa B signaling pathway 💬
 [1] CD40LG 💬 D06193 💬 Toralizumab [1] 63 💬
14 NF-kappa B signaling pathway 💬
 [1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
15 NF-kappa B signaling pathway 💬
 [1] IL1B 💬 D09911 💬 Gevokizumab [4] 41, 50, 56, 269 💬
16 NF-kappa B signaling pathway 💬
 [1] IL1B 💬 D06635 💬 Rilonacept [4] 51, 106, 107, 266 💬
17 NF-kappa B signaling pathway 💬
 [2] IL1B, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
18 NF-kappa B signaling pathway 💬
 [1] IL1R1 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
19 NF-kappa B signaling pathway 💬
 [1] LCK 💬 D03658 💬 Dasatinib [2] 51, 85 💬
20 NF-kappa B signaling pathway 💬
 [1] LCK 💬 D06414 💬 Dasatinib [2] 51, 85 💬
21 NF-kappa B signaling pathway 💬
 [1] LTA 💬 D10187 💬 Pateclizumab [1] 46 💬
22 NF-kappa B signaling pathway 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
23 NF-kappa B signaling pathway 💬
 [1] LTB 💬 D08866 💬 Baminercept [4] 13, 46, 53, 97 💬
24 NF-kappa B signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
25 NF-kappa B signaling pathway 💬
 [1] PARP1 💬 D09730 💬 Olaparib [2] 86, 285 💬
26 NF-kappa B signaling pathway 💬
 [1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
27 NF-kappa B signaling pathway 💬
 [1] PRKCQ 💬 D09671 💬 Sotrastaurin [1] 97 💬
28 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D01545 💬 Aceclofenac [1] 46 💬
29 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
30 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
31 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
32 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D07816 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
33 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00130 💬 Diflunisal [1] 28 💬
34 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00315 💬 Etodolac [1] 46 💬
35 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D03710 💬 Etoricoxib [2] 46, 271 💬
36 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00330 💬 Flurbiprofen [3] 13, 21, 46 💬
37 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00126 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
38 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
39 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00132 💬 Ketoprofen [1] 46 💬
40 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
41 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D08149 💬 Loxoprofen [2] 46, 271 💬
42 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D03714 💬 Lumiracoxib [1] 46 💬
43 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00969 💬 Meloxicam [4] 46, 49, 271, 296 💬
44 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00118 💬 Naproxen [4] 13, 46, 107, 271 💬
45 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D01049 💬 Nimesulide [1] 46 💬
46 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D03716 💬 Parecoxib [2] 46, 271 💬
47 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00568 💬 Rofecoxib [1] 46 💬
48 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00428 💬 Salsalate [1]  5  💬
49 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00120 💬 Sulindac [1] 206 💬
50 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D01183 💬 Tolfenamic acid [1]  5  💬
51 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D02709 💬 Valdecoxib [1] 46 💬
52 NF-kappa B signaling pathway 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
53 NF-kappa B signaling pathway 💬
 [1] SYK 💬 D09347 💬 Fostamatinib [4] 46, 49, 61, 66 💬
54 NF-kappa B signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
55 NF-kappa B signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
56 NF-kappa B signaling pathway 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
57 NF-kappa B signaling pathway 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
58 NF-kappa B signaling pathway 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
59 NF-kappa B signaling pathway 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
60 NF-kappa B signaling pathway 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
61 NF-kappa B signaling pathway 💬
 [1] TNF 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
62 NF-kappa B signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
63 NF-kappa B signaling pathway 💬
 [1] TNFRSF13C 💬 D12151 💬 Ianalumab [7] 35, 46, 49, 53, 61, 63, 95 💬
64 NF-kappa B signaling pathway 💬
 [1] TNFSF11 💬 D03684 💬 Denosumab [8] 46, 50, 70, 93, 95, 96, 274, 299 💬
65 NF-kappa B signaling pathway 💬
 [1] TNFSF13B 💬 D09704 💬 Atacicept [4] 13, 46, 49, 66 💬
66 NF-kappa B signaling pathway 💬
 [1] TNFSF13B 💬 D03068 💬 Belimumab [13] 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬
67 NF-kappa B signaling pathway 💬
 [1] TNFSF13B 💬 D10083 💬 Tabalumab [2] 46, 49 💬
68 NF-kappa B signaling pathway 💬
 [1] TNFSF13B 💬 D11127 💬 Tibulizumab [1] 53 💬