Target Gene/Pathway Pathway / Gene


Search results


No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 AGTR1 [4] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00150 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224
2 AGTR1 [4] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00357 Losartan [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
3 AGTR1 [4] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00400 Valsartan [7] 57, 58, 66, 75, 218, 222, 224
4 AGTR1 [4] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00522 Candesartan cilexetil [1] 67
5 AGTR1 [4] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00522 Candesartan [2] 58, 67
6 AGTR1 [4] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00523 Irbesartan [4] 66, 167, 168, 222
7 AGTR1 [4] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00626 Candesartan cilexetil [1] 67
8 AGTR1 [4] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D00627 Telmisartan [2] 66, 67
9 AGTR1 [4] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D02014 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224
10 AGTR1 [4] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D08146 Losartan [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
11 AGTR1 [4] Phospholipase D signaling pathway, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion D11776 Sparsentan [3] 66, 218, 222
12 EGFR [9] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D01977 Gefitinib [1] 75
13 EGFR [9] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D03455 Cetuximab [5] 34, 51, 86, 89, 331
14 EGFR [9] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D04023 Erlotinib [1] 94
15 EGFR [9] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D04024 Lapatinib [3] 34, 74, 75
16 EGFR [9] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D07907 Erlotinib [1] 94
17 EGFR [9] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D08108 Lapatinib [3] 34, 74, 75
18 EGFR [9] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D11251 Icotinib [1] 34
19 EGFR [9] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D11772 Tesevatinib [1] 67
20 F2 [3] Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton D06410 Thrombomodulin Alfa [1] 85
21 F2 [3] Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton D07144 Dabigatran etexilate [1] 51
22 F2 [3] Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton D09707 Dabigatran [4] 51, 85, 91, 124
23 FCER1A [2] Sphingolipid signaling pathway, Phospholipase D signaling pathway D05251 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299
24 MTOR [10] Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Proteoglycans in cancer, Prostate cancer D00753 Sirolimus [41] 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
25 MTOR [10] Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Proteoglycans in cancer, Prostate cancer D02714 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277
26 MTOR [10] Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Proteoglycans in cancer, Prostate cancer D06068 Temsirolimus [4] 13, 34, 89, 331
27 FYN [6] Sphingolipid signaling pathway, Phospholipase D signaling pathway, Platelet activation, T cell receptor signaling pathway, Prion disease, Viral myocarditis D03658 Dasatinib [2] 51, 85
28 FYN [6] Sphingolipid signaling pathway, Phospholipase D signaling pathway, Platelet activation, T cell receptor signaling pathway, Prion disease, Viral myocarditis D06414 Dasatinib [2] 51, 85
29 CXCR1 [2] Viral protein interaction with cytokine and cytokine receptor, Phospholipase D signaling pathway D08984 Reparixin [2] 298, 299
30 CXCR2 [2] Viral protein interaction with cytokine and cytokine receptor, Phospholipase D signaling pathway D08984 Reparixin [2] 298, 299
31 INSR [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D00085 Insulin human [2] 96, 156
32 INSR [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D03230 Insulin human [2] 96, 156
33 INSR [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D03250 Insulin glargine [1] 299
34 INSR [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D04539 Insulin detemir [1] 299
35 KIT [4] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway D01441 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
36 KIT [4] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway D03658 Dasatinib [2] 51, 85
37 KIT [4] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway D06272 Sorafenib [2] 34, 86
38 KIT [4] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway D06402 Sunitinib [2] 28, 34
39 KIT [4] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway D06414 Dasatinib [2] 51, 85
40 KIT [4] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway D08066 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
41 KIT [4] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway D08524 Sorafenib [2] 34, 86
42 KIT [4] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway D08552 Sunitinib [2] 28, 34
43 KIT [4] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway D08953 Nilotinib [5] 6, 8, 34, 51, 86
44 KIT [4] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway D10229 Masitinib [6] 2, 5, 6, 13, 46, 96
45 KIT [4] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway D11270 Pexidartinib [1] 34
46 PDGFRA [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D01441 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
47 PDGFRA [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D06402 Sunitinib [2] 28, 34
48 PDGFRA [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D08066 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
49 PDGFRA [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D08552 Sunitinib [2] 28, 34
50 PDGFRA [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D08953 Nilotinib [5] 6, 8, 34, 51, 86
51 PDGFRA [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D10481 Nintedanib [5] 51, 85, 89, 227, 228
52 PDGFRB [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D03658 Dasatinib [2] 51, 85
53 PDGFRB [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D06272 Sorafenib [2] 34, 86
54 PDGFRB [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D06402 Sunitinib [2] 28, 34
55 PDGFRB [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D06414 Dasatinib [2] 51, 85
56 PDGFRB [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D08524 Sorafenib [2] 34, 86
57 PDGFRB [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D08552 Sunitinib [2] 28, 34
58 PDGFRB [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D08953 Nilotinib [5] 6, 8, 34, 51, 86
59 PDGFRB [6] Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D10481 Nintedanib [5] 51, 85, 89, 227, 228
60 PIK3CA [29] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib [2] 53, 65
61 PIK3CB [29] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib [2] 53, 65
62 PIK3CD [29] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib [2] 53, 65
63 PIK3CD [29] Platinum drug resistance, Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Prion disease, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11437 Parsaclisib [3] 35, 53, 61
64 AVPR1A [2] Phospholipase D signaling pathway, Vascular smooth muscle contraction D00101 Vasopressin [1] 210
65 AVPR1A [2] Phospholipase D signaling pathway, Vascular smooth muscle contraction D01236 Conivaptan [1] 86
66 AVPR1A [2] Phospholipase D signaling pathway, Vascular smooth muscle contraction D06672 Terlipressin [1] 299
67 AVPR1A [2] Phospholipase D signaling pathway, Vascular smooth muscle contraction D07748 Conivaptan [1] 86
68 AVPR1B [2] Phospholipase D signaling pathway, Vascular smooth muscle contraction D00101 Vasopressin [1] 210
69 AVPR1B [2] Phospholipase D signaling pathway, Vascular smooth muscle contraction D06672 Terlipressin [1] 299
70 AVPR2 [2] Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption D00101 Vasopressin [1] 210
71 AVPR2 [2] Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption D00291 Desmopressin [6] 6, 64, 72, 75, 225, 288
72 AVPR2 [2] Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption D01213 Tolvaptan [3] 67, 72, 225
73 AVPR2 [2] Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption D01236 Conivaptan [1] 86
74 AVPR2 [2] Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption D02235 Desmopressin [6] 6, 64, 72, 75, 225, 288
75 AVPR2 [2] Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption D04752 Lixivaptan [1] 67
76 AVPR2 [2] Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption D06672 Terlipressin [1] 299
77 AVPR2 [2] Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption D07748 Conivaptan [1] 86
78 MAP2K1 [23] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D09666 Selumetinib [1] 34
79 MAP2K1 [23] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10175 Trametinib [4] 2, 34, 279, 280
80 MAP2K1 [23] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10405 Cobimetinib [1] 280
81 MAP2K1 [23] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10604 Binimetinib [1] 34
82 MAP2K2 [20] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D09666 Selumetinib [1] 34
83 MAP2K2 [20] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10175 Trametinib [4] 2, 34, 279, 280
84 MAP2K2 [20] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10405 Cobimetinib [1] 280
85 MAP2K2 [20] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10604 Binimetinib [1] 34
86 PTGFR [1] Phospholipase D signaling pathway D06274 Tafluprost [1] 299
87 PTGFR [1] Phospholipase D signaling pathway D08661 Unoprostone [1] 90
88 RAF1 [20] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer D06272 Sorafenib [2] 34, 86
89 RAF1 [20] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer D08524 Sorafenib [2] 34, 86
90 SYK [5] Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis D09347 Fostamatinib [4] 46, 49, 61, 66