Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Regulation of actin cytoskeleton 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
2 Regulation of actin cytoskeleton 💬
 [3] BRAF, PDGFRB, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
3 Regulation of actin cytoskeleton 💬
 [3] BRAF, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
4 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00113 💬 Atropine [2]  2 , 299 💬
5 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D01077 💬 Atropine [2]  2 , 299 💬
6 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D02069 💬 Atropine [2]  2 , 299 💬
7 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D03011 💬 Atropine [2]  2 , 299 💬
8 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D03814 💬 Atropine [2]  2 , 299 💬
9 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D01000 💬 Bethanechol [1] 98 💬
10 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D11383 💬 Blarcamesine [1] 156 💬
11 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00270 💬 Chlorpromazine [1] 254 💬
12 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00789 💬 Chlorpromazine [1] 254 💬
13 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D03274 💬 Chlorpromazine [1] 254 💬
14 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D04034 💬 Chlorpromazine [1] 254 💬
15 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D02212 💬 Ipratropium [2]  6 , 86 💬
16 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
17 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
18 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00481 💬 Propantheline [1] 26 💬
19 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D08441 💬 Propiverine [1] 226 💬
20 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00765 💬 Rocuronium [1] 296 💬
21 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00138 💬 Scopolamine [1]  2  💬
22 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00787 💬 Trihexyphenidyl [2]  5 ,  6  💬
23 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D08638 💬 Trihexyphenidyl [2]  5 ,  6  💬
24 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00397 💬 Tropicamide [3]  6 , 13, 19 💬
25 Regulation of actin cytoskeleton 💬
 [2] CHRM2, CHRM3 💬 D07226 💬 Fesoterodine [1]  6  💬
26 Regulation of actin cytoskeleton 💬
 [2] CHRM2, CHRM3 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
27 Regulation of actin cytoskeleton 💬
 [2] CHRM2, CHRM3 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
28 Regulation of actin cytoskeleton 💬
 [2] CHRM2, CHRM3 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
29 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 D00661 💬 Cevimeline [1] 53 💬
30 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 D07667 💬 Cevimeline [1] 53 💬
31 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 D01699 💬 Darifenacin [2]  6 , 13 💬
32 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 D03654 💬 Darifenacin [2]  6 , 13 💬
33 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 D01269 💬 Solifenacin [3]  6 , 13, 53 💬
34 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 D08522 💬 Solifenacin [3]  6 , 13, 53 💬
35 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 D00646 💬 Tolterodine [2] 17, 53 💬
36 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 D01148 💬 Tolterodine [2] 17, 53 💬
37 Regulation of actin cytoskeleton 💬
 [1] CXCR4 💬 D08971 💬 Plerixafor [6] 19, 20, 51, 65, 285, 299 💬
38 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
39 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 D04023 💬 Erlotinib [1] 94 💬
40 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
41 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
42 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
43 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 D04024 💬 Lapatinib [3] 34, 74, 75 💬
44 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
45 Regulation of actin cytoskeleton 💬
 [1] EGFR 💬 D11772 💬 Tesevatinib [1] 67 💬
46 Regulation of actin cytoskeleton 💬
 [1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
47 Regulation of actin cytoskeleton 💬
 [1] F2 💬 D07144 💬 Dabigatran etexilate [1] 51 💬
48 Regulation of actin cytoskeleton 💬
 [1] F2 💬 D06410 💬 Thrombomodulin Alfa [1] 85 💬
49 Regulation of actin cytoskeleton 💬
 [1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
50 Regulation of actin cytoskeleton 💬
 [3] FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib [1] 276 💬
51 Regulation of actin cytoskeleton 💬
 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
52 Regulation of actin cytoskeleton 💬
 [1] FGFR2 💬 D05338 💬 Palifermin [5] 13, 36, 38, 39, 65 💬
53 Regulation of actin cytoskeleton 💬
 [1] ITGA4 💬 D06590 💬 Firategrast [1] 13 💬
54 Regulation of actin cytoskeleton 💬
 [1] ITGA4 💬 D06886 💬 Natalizumab [6] 13, 15, 25, 46, 63, 96 💬
55 Regulation of actin cytoskeleton 💬
 [2] ITGA4, ITGB7 💬 D10540 💬 Abrilumab [2] 96, 97 💬
56 Regulation of actin cytoskeleton 💬
 [2] ITGA4, ITGB7 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
57 Regulation of actin cytoskeleton 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
58 Regulation of actin cytoskeleton 💬
 [1] ITGB7 💬 D09901 💬 Etrolizumab [2] 96, 97 💬
59 Regulation of actin cytoskeleton 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
60 Regulation of actin cytoskeleton 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
61 Regulation of actin cytoskeleton 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
62 Regulation of actin cytoskeleton 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
63 Regulation of actin cytoskeleton 💬
 [1] PDGFRA 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
64 Regulation of actin cytoskeleton 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
65 Regulation of actin cytoskeleton 💬
 [2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
66 Regulation of actin cytoskeleton 💬
 [2] PDGFRA, PDGFRB 💬 D06402 💬 Sunitinib [2] 28, 34 💬
67 Regulation of actin cytoskeleton 💬
 [2] PDGFRA, PDGFRB 💬 D08552 💬 Sunitinib [2] 28, 34 💬
68 Regulation of actin cytoskeleton 💬
 [2] PDGFRB, SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
69 Regulation of actin cytoskeleton 💬
 [2] PDGFRB, SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
70 Regulation of actin cytoskeleton 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
71 Regulation of actin cytoskeleton 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
72 Regulation of actin cytoskeleton 💬
 [2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
73 Regulation of actin cytoskeleton 💬
 [1] ROCK2 💬 D11815 💬 Belumosudil [1] 51 💬
74 Regulation of actin cytoskeleton 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
75 Regulation of actin cytoskeleton 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬