Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adrenergic signaling in cardiomyocytes 💬
[1] SCN5A 💬 D00639 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬
2 Adrenergic signaling in cardiomyocytes 💬
[1] SCN5A 💬 D08215 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬
3 Breast cancer 💬
[1] PGR 💬 D09567 💬 Ulipristal [1] 10 💬
4 cAMP signaling pathway 💬
[2] GABBR1, GABBR2 💬 D00241 💬 Baclofen [7]  2 , 10, 13, 18, 65, 149, 206 💬
5 cGMP-PKG signaling pathway 💬
[1] OPRD1 💬 D02095 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
6 cGMP-PKG signaling pathway 💬
[1] OPRD1 💬 D05113 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
7 Chemical carcinogenesis - receptor activation 💬
[1] PGR 💬 D09567 💬 Ulipristal [1] 10 💬
8 Dopaminergic synapse 💬
[1] SCN1A 💬 D00639 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬
9 Dopaminergic synapse 💬
[1] SCN1A 💬 D08215 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬
10 Estrogen signaling pathway 💬
[2] GABBR1, GABBR2 💬 D00241 💬 Baclofen [7]  2 , 10, 13, 18, 65, 149, 206 💬
11 Estrogen signaling pathway 💬
[1] OPRM1 💬 D02095 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
12 Estrogen signaling pathway 💬
[1] OPRM1 💬 D05113 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
13 Estrogen signaling pathway 💬
[1] PGR 💬 D09567 💬 Ulipristal [1] 10 💬
14 GABAergic synapse 💬
[2] GABBR1, GABBR2 💬 D00241 💬 Baclofen [7]  2 , 10, 13, 18, 65, 149, 206 💬
15 GnRH secretion 💬
[2] GABBR1, GABBR2 💬 D00241 💬 Baclofen [7]  2 , 10, 13, 18, 65, 149, 206 💬
16 Morphine addiction 💬
[2] GABBR1, GABBR2 💬 D00241 💬 Baclofen [7]  2 , 10, 13, 18, 65, 149, 206 💬
17 Morphine addiction 💬
[1] OPRM1 💬 D02095 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
18 Morphine addiction 💬
[1] OPRM1 💬 D05113 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
19 Neuroactive ligand-receptor interaction 💬
[2] GABBR1, GABBR2 💬 D00241 💬 Baclofen [7]  2 , 10, 13, 18, 65, 149, 206 💬
20 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 D02095 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
21 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 D05113 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
22 Oocyte meiosis 💬
[1] PGR 💬 D09567 💬 Ulipristal [1] 10 💬
23 Progesterone-mediated oocyte maturation 💬
[1] PGR 💬 D09567 💬 Ulipristal [1] 10 💬
24 Sphingolipid signaling pathway 💬
[1] OPRD1 💬 D02095 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
25 Sphingolipid signaling pathway 💬
[1] OPRD1 💬 D05113 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
26 Taste transduction 💬
[2] GABBR1, GABBR2 💬 D00241 💬 Baclofen [7]  2 , 10, 13, 18, 65, 149, 206 💬
27 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 D00639 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬
28 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 D08215 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬