Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Apelin signaling pathway 💬
[1] PDE3B 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
2 Calcium signaling pathway 💬
[1] TBXA2R 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
3 cAMP signaling pathway 💬
[2] PDE3A, PDE3B 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
4 cGMP-PKG signaling pathway 💬
[2] PDE3A, PDE3B 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
5 Cholinergic synapse 💬
[1] ACHE 💬 D00670 💬 Donepezil [9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
6 Cholinergic synapse 💬
[1] ACHE 💬 D07869 💬 Donepezil [9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
7 Complement and coagulation cascades 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
8 Coronavirus disease - COVID-19 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
9 Glucagon signaling pathway 💬
[1] PDE3B 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
10 Glycerophospholipid metabolism 💬
[1] ACHE 💬 D00670 💬 Donepezil [9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
11 Glycerophospholipid metabolism 💬
[1] ACHE 💬 D07869 💬 Donepezil [9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
12 Insulin signaling pathway 💬
[1] PDE3B 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
13 Metabolic pathways 💬
[2] PDE3A, PDE3B 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
14 Morphine addiction 💬
[2] PDE3A, PDE3B 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
15 Neuroactive ligand-receptor interaction 💬
[1] CALCA 💬 D11055 💬 Fremanezumab [2] 124, 226 💬
16 Neuroactive ligand-receptor interaction 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
17 Neuroactive ligand-receptor interaction 💬
[1] TBXA2R 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
18 Pathogenic Escherichia coli infection 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
19 Pathways in cancer 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
20 Phospholipase D signaling pathway 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
21 Platelet activation 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
22 Platelet activation 💬
[1] TBXA2R 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
23 Progesterone-mediated oocyte maturation 💬
[1] PDE3B 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
24 Purine metabolism 💬
[2] PDE3A, PDE3B 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
25 Regulation of actin cytoskeleton 💬
[1] F2 💬 D09707 💬 Dabigatran [4] 51, 85, 91, 124 💬
26 Regulation of lipolysis in adipocytes 💬
[1] PDE3B 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
27 Renin secretion 💬
[2] PDE3A, PDE3B 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
28 Vascular smooth muscle contraction 💬
[1] CALCA 💬 D11055 💬 Fremanezumab [2] 124, 226 💬