Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [14]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
2 Alanine, aspartate and glutamate metabolism 💬
 [4] ABAT, ALDH5A1, GAD1, GAD2 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
3 Alcoholism 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
4 Aldosterone synthesis and secretion 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
5 Alzheimer disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
6 Alzheimer disease 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
7 Alzheimer disease 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
8 Amphetamine addiction 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
9 Amyotrophic lateral sclerosis 💬
 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
10 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
11 Arachidonic acid metabolism 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
12 beta-Alanine metabolism 💬
 [3] ABAT, GAD1, GAD2 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
13 Butanoate metabolism 💬
 [4] ABAT, ALDH5A1, GAD1, GAD2 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
14 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
15 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
16 Calcium signaling pathway 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [14]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
17 Calcium signaling pathway 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
18 Calcium signaling pathway 💬
 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
19 Calcium signaling pathway 💬
 [1] TNNC2 💬 D11363 💬 Reldesemtiv [2]  2 ,  3  💬
20 cAMP signaling pathway 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [14]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
21 cAMP signaling pathway 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
22 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [14]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
23 Chemical carcinogenesis - DNA adducts 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
24 Chemical carcinogenesis - DNA adducts 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
25 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [14]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
26 Chemical carcinogenesis - receptor activation 💬
 [1] AR 💬 D00075 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
27 Chemical carcinogenesis - receptor activation 💬
 [1] AR 💬 D00957 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
28 Chemical carcinogenesis - receptor activation 💬
 [1] AR 💬 D00958 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
29 Chemical carcinogenesis - receptor activation 💬
 [1] AR 💬 D00959 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
30 Chemical carcinogenesis - receptor activation 💬
 [1] AR 💬 D06085 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
31 Chemical carcinogenesis - receptor activation 💬
 [1] AR 💬 D06087 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
32 Cholinergic synapse 💬
 [1] ACHE 💬 D00487 💬 Pyridostigmine [4]  3 ,  6 , 11, 256 💬
33 Circadian entrainment 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
34 Circadian entrainment 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
35 Cocaine addiction 💬
 [6] GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
36 Cortisol synthesis and secretion 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
37 Cortisol synthesis and secretion 💬
 [1] KCNA4 💬 D10228 💬 Amifampridine [3]  3 , 11, 12 💬
38 Cortisol synthesis and secretion 💬
 [1] KCNA4 💬 D04127 💬 Dalfampridine [5]  3 ,  4 ,  6 , 13, 14 💬
39 Cushing syndrome 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
40 Cushing syndrome 💬
 [1] KCNA4 💬 D10228 💬 Amifampridine [3]  3 , 11, 12 💬
41 Cushing syndrome 💬
 [1] KCNA4 💬 D04127 💬 Dalfampridine [5]  3 ,  4 ,  6 , 13, 14 💬
42 Cytokine-cytokine receptor interaction 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
43 Cytokine-cytokine receptor interaction 💬
 [1] MSTN 💬 D11797 💬 Apitegromab [1]  3  💬
44 Dopaminergic synapse 💬
 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
45 Drug metabolism - other enzymes 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
46 GABAergic synapse 💬
 [3] ABAT, GAD1, GAD2 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
47 GABAergic synapse 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00550 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
48 GABAergic synapse 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00696 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
49 GABAergic synapse 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D05028 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
50 Glutamatergic synapse 💬
 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
51 Glutathione metabolism 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
52 Glycerophospholipid metabolism 💬
 [1] ACHE 💬 D00487 💬 Pyridostigmine [4]  3 ,  6 , 11, 256 💬
53 GnRH secretion 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
54 GnRH signaling pathway 💬
 [1] GNRHR 💬 D00989 💬 Leuprolide [5]  1 ,  2 ,  3 , 51, 76 💬
55 Growth hormone synthesis, secretion and action 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
56 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
57 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
58 Human papillomavirus infection 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
59 Human papillomavirus infection 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
60 Huntington disease 💬
 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
61 IL-17 signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
62 IL-17 signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
63 JAK-STAT signaling pathway 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
64 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
65 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
66 Leishmaniasis 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
67 Leishmaniasis 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
68 Long-term depression 💬
 [3] GRIA1, GRIA2, GRIA3 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
69 Long-term potentiation 💬
 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
70 MAPK signaling pathway 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
71 Metabolic pathways 💬
 [4] ABAT, ALDH5A1, GAD1, GAD2 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
72 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
73 Metabolic pathways 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
74 Metabolic pathways 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
75 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
76 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
77 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00550 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
78 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00696 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
79 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D05028 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
80 Neuroactive ligand-receptor interaction 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [14]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
81 Neuroactive ligand-receptor interaction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00550 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
82 Neuroactive ligand-receptor interaction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00696 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
83 Neuroactive ligand-receptor interaction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D05028 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
84 Neuroactive ligand-receptor interaction 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
85 Neuroactive ligand-receptor interaction 💬
 [1] GNRHR 💬 D00989 💬 Leuprolide [5]  1 ,  2 ,  3 , 51, 76 💬
86 Neuroactive ligand-receptor interaction 💬
 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
87 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00472 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
88 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00980 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
89 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00981 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
90 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00982 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
91 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01239 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
92 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01998 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
93 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02156 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
94 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D03301 💬 Prednisolone [43]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬
95 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
96 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
97 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00550 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
98 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00696 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
99 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D05028 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
100 Nicotine addiction 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
101 Nucleocytoplasmic transport 💬
 [1] SMN2 💬 D11406 💬 Risdiplam [1]  3  💬
102 Oocyte meiosis 💬
 [1] AR 💬 D00075 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
103 Oocyte meiosis 💬
 [1] AR 💬 D00957 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
104 Oocyte meiosis 💬
 [1] AR 💬 D00958 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
105 Oocyte meiosis 💬
 [1] AR 💬 D00959 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
106 Oocyte meiosis 💬
 [1] AR 💬 D06085 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
107 Oocyte meiosis 💬
 [1] AR 💬 D06087 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
108 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
109 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
110 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
111 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
112 p53 signaling pathway 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
113 Pathways in cancer 💬
 [1] AR 💬 D00075 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
114 Pathways in cancer 💬
 [1] AR 💬 D00957 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
115 Pathways in cancer 💬
 [1] AR 💬 D00958 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
116 Pathways in cancer 💬
 [1] AR 💬 D00959 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
117 Pathways in cancer 💬
 [1] AR 💬 D06085 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
118 Pathways in cancer 💬
 [1] AR 💬 D06087 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
119 Pathways in cancer 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
120 Pathways in cancer 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
121 Pathways of neurodegeneration - multiple diseases 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
122 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
123 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
124 PI3K-Akt signaling pathway 💬
 [1] GHR 💬 D02691 💬 Somatotropin [23]  2 ,  3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬
125 Platelet activation 💬
 [1] PTGS1 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
126 Prion disease 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
127 Propanoate metabolism 💬
 [1] ABAT 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
128 Prostate cancer 💬
 [1] AR 💬 D00075 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
129 Prostate cancer 💬
 [1] AR 💬 D00957 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
130 Prostate cancer 💬
 [1] AR 💬 D00958 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
131 Prostate cancer 💬
 [1] AR 💬 D00959 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
132 Prostate cancer 💬
 [1] AR 💬 D06085 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
133 Prostate cancer 💬
 [1] AR 💬 D06087 💬 Testosterone [9]  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
134 Purine metabolism 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
135 Pyrimidine metabolism 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
136 Rap1 signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
137 Ras signaling pathway 💬
 [3] GRIN1, GRIN2A, GRIN2B 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
138 Regulation of lipolysis in adipocytes 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [14]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
139 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
140 Regulation of lipolysis in adipocytes 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
141 Renin secretion 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [14]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
142 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00550 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
143 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00696 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
144 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D05028 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
145 Retrograde endocannabinoid signaling 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
146 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
147 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
148 Salivary secretion 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [14]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
149 Serotonergic synapse 💬
 [3] GABRB1, GABRB2, GABRB3 💬 D00550 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
150 Serotonergic synapse 💬
 [3] GABRB1, GABRB2, GABRB3 💬 D00696 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
151 Serotonergic synapse 💬
 [3] GABRB1, GABRB2, GABRB3 💬 D05028 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
152 Serotonergic synapse 💬
 [1] KCND2 💬 D10228 💬 Amifampridine [3]  3 , 11, 12 💬
153 Serotonergic synapse 💬
 [1] KCND2 💬 D04127 💬 Dalfampridine [5]  3 ,  4 ,  6 , 13, 14 💬
154 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
155 Serotonergic synapse 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
156 Small cell lung cancer 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
157 Small cell lung cancer 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
158 Spinocerebellar ataxia 💬
 [8] GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
159 Spinocerebellar ataxia 💬
 [2] KCNC3, KCND3 💬 D10228 💬 Amifampridine [3]  3 , 11, 12 💬
160 Spinocerebellar ataxia 💬
 [2] KCNC3, KCND3 💬 D04127 💬 Dalfampridine [5]  3 ,  4 ,  6 , 13, 14 💬
161 Systemic lupus erythematosus 💬
 [2] GRIN2A, GRIN2B 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
162 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00550 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
163 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00696 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
164 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D05028 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 272, 298 💬
165 Taurine and hypotaurine metabolism 💬
 [2] GAD1, GAD2 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
166 TNF signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
167 TNF signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
168 Transcriptional misregulation in cancer 💬
 [1] GRIA3 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
169 Type I diabetes mellitus 💬
 [2] GAD1, GAD2 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
170 Type II diabetes mellitus 💬
 [1] CACNA1G 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
171 Valine, leucine and isoleucine degradation 💬
 [1] ABAT 💬 D00399 💬 Valproic acid [17]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
172 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [18]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
173 VEGF signaling pathway 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬

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