Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
2 Acute myeloid leukemia 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
3 Acute myeloid leukemia 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
4 Acute myeloid leukemia 💬
 [1] RARA 💬 D06543 💬 Vitamin A [3] 13, 53, 90 💬
5 Adipocytokine signaling pathway 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
6 Adipocytokine signaling pathway 💬
 [1] JAK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
7 Adipocytokine signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
8 Adipocytokine signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
9 Adipocytokine signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
10 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 D01450 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
11 Adrenergic signaling in cardiomyocytes 💬
 [1] SCN5A 💬 D07552 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
12 African trypanosomiasis 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
13 African trypanosomiasis 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
14 African trypanosomiasis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
15 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
16 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] JAK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
17 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
18 AGE-RAGE signaling pathway in diabetic complications 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
19 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
20 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
21 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
22 Alcoholic liver disease 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
23 Alcoholic liver disease 💬
 [1] IL17A 💬 D11127 💬 Tibulizumab [1] 53 💬
24 Alcoholic liver disease 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
25 Alcoholic liver disease 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
26 Alcoholic liver disease 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
27 Aldosterone-regulated sodium reabsorption 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
28 Aldosterone-regulated sodium reabsorption 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
29 Allograft rejection 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
30 Allograft rejection 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
31 Allograft rejection 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
32 Allograft rejection 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
33 Allograft rejection 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
34 Allograft rejection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
35 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
36 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
37 Alzheimer disease 💬
 [1] CHRM3 💬 D00661 💬 Cevimeline [1] 53 💬
38 Alzheimer disease 💬
 [1] CHRM3 💬 D07667 💬 Cevimeline [1] 53 💬
39 Alzheimer disease 💬
 [1] CHRM3 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
40 Alzheimer disease 💬
 [1] CHRM3 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
41 Alzheimer disease 💬
 [1] CHRM3 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
42 Alzheimer disease 💬
 [1] CHRM3 💬 D01269 💬 Solifenacin [3]  6 , 13, 53 💬
43 Alzheimer disease 💬
 [1] CHRM3 💬 D08522 💬 Solifenacin [3]  6 , 13, 53 💬
44 Alzheimer disease 💬
 [1] CHRM3 💬 D00646 💬 Tolterodine [2] 17, 53 💬
45 Alzheimer disease 💬
 [1] CHRM3 💬 D01148 💬 Tolterodine [2] 17, 53 💬
46 Alzheimer disease 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
47 Alzheimer disease 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
48 Alzheimer disease 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
49 Alzheimer disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
50 Alzheimer disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
51 Alzheimer disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
52 Alzheimer disease 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
53 Alzheimer disease 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
54 Amoebiasis 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
55 Amoebiasis 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
56 Amoebiasis 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
57 Amoebiasis 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
58 Amoebiasis 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
59 Amoebiasis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
60 Amphetamine addiction 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
61 Amphetamine addiction 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
62 Amphetamine addiction 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
63 AMPK signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
64 AMPK signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
65 Amyotrophic lateral sclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
66 Amyotrophic lateral sclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
67 Amyotrophic lateral sclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
68 Amyotrophic lateral sclerosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
69 Amyotrophic lateral sclerosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
70 Antifolate resistance 💬
 [2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
71 Antifolate resistance 💬
 [2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
72 Antifolate resistance 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
73 Antifolate resistance 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
74 Antifolate resistance 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
75 Antigen processing and presentation 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
76 Antigen processing and presentation 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
77 Apoptosis 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
78 Apoptosis 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
79 Apoptosis 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
80 Apoptosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
81 Apoptosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
82 Apoptosis - multiple species 💬
 [1] NGFR 💬 D11028 💬 Cenegermin [2] 53, 90 💬
83 Asthma 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
84 Asthma 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
85 Asthma 💬
 [1] FCER1A 💬 D05251 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
86 Asthma 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
87 Asthma 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
88 Autoimmune thyroid disease 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
89 Autoimmune thyroid disease 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
90 Autoimmune thyroid disease 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
91 Autophagy - animal 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
92 Autophagy - animal 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
93 Axon guidance 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
94 Axon guidance 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
95 Axon guidance 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
96 Axon guidance 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
97 Axon guidance 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
98 B cell receptor signaling pathway 💬
 [1] BTK 💬 D11478 💬 Branebrutinib [3] 46, 49, 53 💬
99 B cell receptor signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
100 B cell receptor signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
101 B cell receptor signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
102 B cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
103 B cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
104 B cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
105 Bacterial invasion of epithelial cells 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
106 Bacterial invasion of epithelial cells 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
107 Biosynthesis of cofactors 💬
 [2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
108 Biosynthesis of cofactors 💬
 [2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
109 Biosynthesis of cofactors 💬
 [1] DHODH 💬 D00749 💬 Leflunomide [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬
110 Breast cancer 💬
 [2] ESR1, ESR2 💬 D11513 💬 Estetrol [1] 53 💬
111 Breast cancer 💬
 [2] ESR1, ESR2 💬 D11514 💬 Estetrol [1] 53 💬
112 Breast cancer 💬
 [2] ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
113 Breast cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
114 Breast cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
115 C-type lectin receptor signaling pathway 💬
 [3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
116 C-type lectin receptor signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
117 C-type lectin receptor signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
118 C-type lectin receptor signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
119 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
120 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
121 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
122 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
123 C-type lectin receptor signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
124 Calcium signaling pathway 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
125 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
126 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
127 Calcium signaling pathway 💬
 [2] CHRM2, CHRM3 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
128 Calcium signaling pathway 💬
 [2] CHRM2, CHRM3 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
129 Calcium signaling pathway 💬
 [2] CHRM2, CHRM3 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
130 Calcium signaling pathway 💬
 [1] CHRM3 💬 D00661 💬 Cevimeline [1] 53 💬
131 Calcium signaling pathway 💬
 [1] CHRM3 💬 D07667 💬 Cevimeline [1] 53 💬
132 Calcium signaling pathway 💬
 [1] CHRM3 💬 D01269 💬 Solifenacin [3]  6 , 13, 53 💬
133 Calcium signaling pathway 💬
 [1] CHRM3 💬 D08522 💬 Solifenacin [3]  6 , 13, 53 💬
134 Calcium signaling pathway 💬
 [1] CHRM3 💬 D00646 💬 Tolterodine [2] 17, 53 💬
135 Calcium signaling pathway 💬
 [1] CHRM3 💬 D01148 💬 Tolterodine [2] 17, 53 💬
136 Calcium signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
137 Calcium signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
138 Calcium signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
139 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
140 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
141 cAMP signaling pathway 💬
 [1] CHRM2 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
142 cAMP signaling pathway 💬
 [1] CHRM2 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
143 cAMP signaling pathway 💬
 [1] CHRM2 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
144 cAMP signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
145 cAMP signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
146 cAMP signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
147 Carbohydrate digestion and absorption 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
148 Carbohydrate digestion and absorption 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
149 Cell adhesion molecules 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
150 Cell adhesion molecules 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
151 Cell adhesion molecules 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
152 Cell adhesion molecules 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
153 Cell adhesion molecules 💬
 [1] PDCD1 💬 D10316 💬 Nivolumab [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
154 Cellular senescence 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
155 Cellular senescence 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
156 Cellular senescence 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
157 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
158 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
159 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
160 Central carbon metabolism in cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
161 Central carbon metabolism in cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
162 cGMP-PKG signaling pathway 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
163 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
164 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
165 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
166 Chagas disease 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
167 Chagas disease 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
168 Chagas disease 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
169 Chagas disease 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
170 Chagas disease 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
171 Chagas disease 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
172 Chemical carcinogenesis - reactive oxygen species 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
173 Chemical carcinogenesis - reactive oxygen species 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
174 Chemical carcinogenesis - reactive oxygen species 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
175 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
176 Chemical carcinogenesis - receptor activation 💬
 [3] AR, ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
177 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D11513 💬 Estetrol [1] 53 💬
178 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 D11514 💬 Estetrol [1] 53 💬
179 Chemical carcinogenesis - receptor activation 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
180 Chemical carcinogenesis - receptor activation 💬
 [1] JAK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
181 Chemical carcinogenesis - receptor activation 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
182 Chemical carcinogenesis - receptor activation 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
183 Chemical carcinogenesis - receptor activation 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
184 Chemical carcinogenesis - receptor activation 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [25]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
185 Chemokine signaling pathway 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
186 Chemokine signaling pathway 💬
 [2] JAK2, JAK3 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
187 Chemokine signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
188 Chemokine signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
189 Chemokine signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
190 Choline metabolism in cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
191 Choline metabolism in cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
192 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
193 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
194 Cholinergic synapse 💬
 [2] CHRM2, CHRM3 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
195 Cholinergic synapse 💬
 [2] CHRM2, CHRM3 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
196 Cholinergic synapse 💬
 [2] CHRM2, CHRM3 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
197 Cholinergic synapse 💬
 [1] CHRM3 💬 D00661 💬 Cevimeline [1] 53 💬
198 Cholinergic synapse 💬
 [1] CHRM3 💬 D07667 💬 Cevimeline [1] 53 💬
199 Cholinergic synapse 💬
 [1] CHRM3 💬 D01269 💬 Solifenacin [3]  6 , 13, 53 💬
200 Cholinergic synapse 💬
 [1] CHRM3 💬 D08522 💬 Solifenacin [3]  6 , 13, 53 💬
201 Cholinergic synapse 💬
 [1] CHRM3 💬 D00646 💬 Tolterodine [2] 17, 53 💬
202 Cholinergic synapse 💬
 [1] CHRM3 💬 D01148 💬 Tolterodine [2] 17, 53 💬
203 Cholinergic synapse 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
204 Cholinergic synapse 💬
 [1] JAK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
205 Cholinergic synapse 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
206 Cholinergic synapse 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
207 Chronic myeloid leukemia 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
208 Chronic myeloid leukemia 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
209 Chronic myeloid leukemia 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
210 Cocaine addiction 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
211 Colorectal cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
212 Colorectal cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
213 Coronavirus disease - COVID-19 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
214 Coronavirus disease - COVID-19 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
215 Coronavirus disease - COVID-19 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
216 Coronavirus disease - COVID-19 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
217 Coronavirus disease - COVID-19 💬
 [2] JAK1, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
218 Coronavirus disease - COVID-19 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
219 Coronavirus disease - COVID-19 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
220 Coronavirus disease - COVID-19 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
221 Coronavirus disease - COVID-19 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
222 Coronavirus disease - COVID-19 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
223 Cytokine-cytokine receptor interaction 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
224 Cytokine-cytokine receptor interaction 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
225 Cytokine-cytokine receptor interaction 💬
 [3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
226 Cytokine-cytokine receptor interaction 💬
 [2] IL17A, TNFSF13B 💬 D11127 💬 Tibulizumab [1] 53 💬
227 Cytokine-cytokine receptor interaction 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
228 Cytokine-cytokine receptor interaction 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
229 Cytokine-cytokine receptor interaction 💬
 [1] LTB 💬 D08866 💬 Baminercept [4] 13, 46, 53, 97 💬
230 Cytokine-cytokine receptor interaction 💬
 [1] NGFR 💬 D11028 💬 Cenegermin [2] 53, 90 💬
231 Cytokine-cytokine receptor interaction 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
232 Cytokine-cytokine receptor interaction 💬
 [1] TNFRSF13C 💬 D12151 💬 Ianalumab [5] 35, 46, 49, 53, 95 💬
233 Cytokine-cytokine receptor interaction 💬
 [1] TNFSF13B 💬 D03068 💬 Belimumab [12] 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300 💬
234 Cytosolic DNA-sensing pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
235 Diabetic cardiomyopathy 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
236 Diabetic cardiomyopathy 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
237 Diabetic cardiomyopathy 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
238 Dilated cardiomyopathy 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
239 Dilated cardiomyopathy 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
240 Dopaminergic synapse 💬
 [3] PPP3CA, PPP3CB, PPP3CC 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
241 Dopaminergic synapse 💬
 [3] PPP3CA, PPP3CB, PPP3CC 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
242 Dopaminergic synapse 💬
 [3] PPP3CA, PPP3CB, PPP3CC 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
243 Dopaminergic synapse 💬
 [1] SCN1A 💬 D01450 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
244 Dopaminergic synapse 💬
 [1] SCN1A 💬 D07552 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
245 Drug metabolism - other enzymes 💬
 [2] IMPDH1, IMPDH2 💬 D01392 💬 Mizoribine [8] 46, 49, 51, 53, 66, 94, 222, 224 💬
246 Drug metabolism - other enzymes 💬
 [2] IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
247 Drug metabolism - other enzymes 💬
 [2] IMPDH1, IMPDH2 💬 D05094 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
248 Drug metabolism - other enzymes 💬
 [2] IMPDH1, IMPDH2 💬 D05095 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
249 Drug metabolism - other enzymes 💬
 [2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [36]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
250 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
251 EGFR tyrosine kinase inhibitor resistance 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
252 EGFR tyrosine kinase inhibitor resistance 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
253 EGFR tyrosine kinase inhibitor resistance 💬
 [2] JAK1, JAK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
254 EGFR tyrosine kinase inhibitor resistance 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
255 EGFR tyrosine kinase inhibitor resistance 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
256 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D11513 💬 Estetrol [1] 53 💬
257 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D11514 💬 Estetrol [1] 53 💬
258 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
259 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [25]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
260 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D11513 💬 Estetrol [1] 53 💬
261 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D11514 💬 Estetrol [1] 53 💬
262 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
263 Endocrine resistance 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
264 Endocrine resistance 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
265 Endometrial cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
266 Endometrial cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
267 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
268 Epstein-Barr virus infection 💬
 [1] BTK 💬 D11478 💬 Branebrutinib [3] 46, 49, 53 💬
269 Epstein-Barr virus infection 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
270 Epstein-Barr virus infection 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
271 Epstein-Barr virus infection 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
272 Epstein-Barr virus infection 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
273 Epstein-Barr virus infection 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
274 Epstein-Barr virus infection 💬
 [3] JAK1, JAK3, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
275 Epstein-Barr virus infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
276 Epstein-Barr virus infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
277 Epstein-Barr virus infection 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
278 Epstein-Barr virus infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
279 Epstein-Barr virus infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
280 ErbB signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
281 ErbB signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
282 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D11513 💬 Estetrol [1] 53 💬
283 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D11514 💬 Estetrol [1] 53 💬
284 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
285 Estrogen signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
286 Estrogen signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
287 Estrogen signaling pathway 💬
 [1] RARA 💬 D06543 💬 Vitamin A [3] 13, 53, 90 💬
288 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 D11478 💬 Branebrutinib [3] 46, 49, 53 💬
289 Fc epsilon RI signaling pathway 💬
 [1] FCER1A 💬 D05251 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
290 Fc epsilon RI signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
291 Fc epsilon RI signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
292 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
293 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
294 Fc gamma R-mediated phagocytosis 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
295 Fc gamma R-mediated phagocytosis 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
296 Fluid shear stress and atherosclerosis 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
297 Fluid shear stress and atherosclerosis 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
298 Fluid shear stress and atherosclerosis 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
299 Fluid shear stress and atherosclerosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
300 Fluid shear stress and atherosclerosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
301 Focal adhesion 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
302 Focal adhesion 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
303 Folate biosynthesis 💬
 [2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
304 Folate biosynthesis 💬
 [2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
305 FoxO signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
306 FoxO signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
307 Gastric acid secretion 💬
 [1] CHRM3 💬 D00661 💬 Cevimeline [1] 53 💬
308 Gastric acid secretion 💬
 [1] CHRM3 💬 D07667 💬 Cevimeline [1] 53 💬
309 Gastric acid secretion 💬
 [1] CHRM3 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
310 Gastric acid secretion 💬
 [1] CHRM3 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
311 Gastric acid secretion 💬
 [1] CHRM3 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
312 Gastric acid secretion 💬
 [1] CHRM3 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
313 Gastric acid secretion 💬
 [1] CHRM3 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
314 Gastric acid secretion 💬
 [1] CHRM3 💬 D01269 💬 Solifenacin [3]  6 , 13, 53 💬
315 Gastric acid secretion 💬
 [1] CHRM3 💬 D08522 💬 Solifenacin [3]  6 , 13, 53 💬
316 Gastric acid secretion 💬
 [1] CHRM3 💬 D00646 💬 Tolterodine [2] 17, 53 💬
317 Gastric acid secretion 💬
 [1] CHRM3 💬 D01148 💬 Tolterodine [2] 17, 53 💬
318 Gastric cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
319 Gastric cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
320 Gastric cancer 💬
 [1] RARB 💬 D06543 💬 Vitamin A [3] 13, 53, 90 💬
321 Glioma 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
322 Glioma 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
323 Glucagon signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
324 Glucagon signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
325 Glucagon signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
326 Glutamatergic synapse 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
327 Glutamatergic synapse 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
328 Glutamatergic synapse 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
329 GnRH secretion 💬
 [1] ESR2 💬 D11513 💬 Estetrol [1] 53 💬
330 GnRH secretion 💬
 [1] ESR2 💬 D11514 💬 Estetrol [1] 53 💬
331 GnRH secretion 💬
 [1] ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
332 GnRH secretion 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
333 GnRH secretion 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
334 Graft-versus-host disease 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
335 Graft-versus-host disease 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
336 Graft-versus-host disease 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
337 Growth hormone synthesis, secretion and action 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
338 Growth hormone synthesis, secretion and action 💬
 [1] JAK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
339 Growth hormone synthesis, secretion and action 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
340 Growth hormone synthesis, secretion and action 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
341 Hematopoietic cell lineage 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
342 Hematopoietic cell lineage 💬
 [1] MS4A1 💬 D02994 💬 Rituximab [49]  6 , 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
343 Hematopoietic cell lineage 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
344 Hematopoietic cell lineage 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
345 Hepatitis B 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
346 Hepatitis B 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
347 Hepatitis B 💬
 [4] JAK1, JAK2, JAK3, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
348 Hepatitis B 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
349 Hepatitis B 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
350 Hepatitis B 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
351 Hepatitis B 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
352 Hepatitis B 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
353 Hepatitis C 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
354 Hepatitis C 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
355 Hepatitis C 💬
 [2] JAK1, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
356 Hepatitis C 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
357 Hepatitis C 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
358 Hepatitis C 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
359 Hepatitis C 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
360 Hepatitis C 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
361 Hepatocellular carcinoma 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
362 Hepatocellular carcinoma 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
363 Herpes simplex virus 1 infection 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
364 Herpes simplex virus 1 infection 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
365 Herpes simplex virus 1 infection 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
366 Herpes simplex virus 1 infection 💬
 [3] JAK1, JAK2, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
367 Herpes simplex virus 1 infection 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
368 Herpes simplex virus 1 infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
369 Herpes simplex virus 1 infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
370 Herpes simplex virus 1 infection 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
371 Herpes simplex virus 1 infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
372 HIF-1 signaling pathway 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
373 HIF-1 signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
374 HIF-1 signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
375 HIF-1 signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
376 Human cytomegalovirus infection 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
377 Human cytomegalovirus infection 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
378 Human cytomegalovirus infection 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
379 Human cytomegalovirus infection 💬
 [1] JAK1 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
380 Human cytomegalovirus infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
381 Human cytomegalovirus infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
382 Human cytomegalovirus infection 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
383 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
384 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
385 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
386 Human cytomegalovirus infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
387 Human cytomegalovirus infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
388 Human immunodeficiency virus 1 infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
389 Human immunodeficiency virus 1 infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
390 Human immunodeficiency virus 1 infection 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
391 Human immunodeficiency virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
392 Human immunodeficiency virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
393 Human immunodeficiency virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
394 Human immunodeficiency virus 1 infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
395 Human immunodeficiency virus 1 infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
396 Human papillomavirus infection 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
397 Human papillomavirus infection 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
398 Human papillomavirus infection 💬
 [2] JAK1, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
399 Human papillomavirus infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
400 Human papillomavirus infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
401 Human papillomavirus infection 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
402 Human papillomavirus infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
403 Human papillomavirus infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
404 Human T-cell leukemia virus 1 infection 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
405 Human T-cell leukemia virus 1 infection 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
406 Human T-cell leukemia virus 1 infection 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
407 Human T-cell leukemia virus 1 infection 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
408 Human T-cell leukemia virus 1 infection 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
409 Human T-cell leukemia virus 1 infection 💬
 [2] JAK1, JAK3 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
410 Human T-cell leukemia virus 1 infection 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
411 Human T-cell leukemia virus 1 infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
412 Human T-cell leukemia virus 1 infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
413 Human T-cell leukemia virus 1 infection 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
414 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
415 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
416 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
417 Human T-cell leukemia virus 1 infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
418 Human T-cell leukemia virus 1 infection 💬
 [1] TNFRSF13C 💬 D12151 💬 Ianalumab [5] 35, 46, 49, 53, 95 💬
419 Hypertrophic cardiomyopathy 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
420 Hypertrophic cardiomyopathy 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
421 IL-17 signaling pathway 💬
 [1] IL17A 💬 D11127 💬 Tibulizumab [1] 53 💬
422 IL-17 signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
423 IL-17 signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
424 IL-17 signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
425 Inflammatory bowel disease 💬
 [3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
426 Inflammatory bowel disease 💬
 [1] IL17A 💬 D11127 💬 Tibulizumab [1] 53 💬
427 Inflammatory bowel disease 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
428 Inflammatory bowel disease 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
429 Inflammatory bowel disease 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
430 Inflammatory mediator regulation of TRP channels 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
431 Inflammatory mediator regulation of TRP channels 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
432 Influenza A 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
433 Influenza A 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
434 Influenza A 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
435 Influenza A 💬
 [3] JAK1, JAK2, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
436 Influenza A 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
437 Influenza A 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
438 Influenza A 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
439 Influenza A 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
440 Influenza A 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
441 Inositol phosphate metabolism 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
442 Inositol phosphate metabolism 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
443 Insulin resistance 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
444 Insulin resistance 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
445 Insulin resistance 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
446 Insulin resistance 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
447 Insulin resistance 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
448 Insulin secretion 💬
 [1] CHRM3 💬 D00661 💬 Cevimeline [1] 53 💬
449 Insulin secretion 💬
 [1] CHRM3 💬 D07667 💬 Cevimeline [1] 53 💬
450 Insulin secretion 💬
 [1] CHRM3 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
451 Insulin secretion 💬
 [1] CHRM3 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
452 Insulin secretion 💬
 [1] CHRM3 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
453 Insulin secretion 💬
 [1] CHRM3 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
454 Insulin secretion 💬
 [1] CHRM3 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
455 Insulin secretion 💬
 [1] CHRM3 💬 D01269 💬 Solifenacin [3]  6 , 13, 53 💬
456 Insulin secretion 💬
 [1] CHRM3 💬 D08522 💬 Solifenacin [3]  6 , 13, 53 💬
457 Insulin secretion 💬
 [1] CHRM3 💬 D00646 💬 Tolterodine [2] 17, 53 💬
458 Insulin secretion 💬
 [1] CHRM3 💬 D01148 💬 Tolterodine [2] 17, 53 💬
459 Insulin signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
460 Insulin signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
461 Intestinal immune network for IgA production 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
462 Intestinal immune network for IgA production 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
463 Intestinal immune network for IgA production 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
464 Intestinal immune network for IgA production 💬
 [1] TNFRSF13C 💬 D12151 💬 Ianalumab [5] 35, 46, 49, 53, 95 💬
465 Intestinal immune network for IgA production 💬
 [1] TNFSF13B 💬 D03068 💬 Belimumab [12] 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300 💬
466 Intestinal immune network for IgA production 💬
 [1] TNFSF13B 💬 D11127 💬 Tibulizumab [1] 53 💬
467 JAK-STAT signaling pathway 💬
 [3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
468 JAK-STAT signaling pathway 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
469 JAK-STAT signaling pathway 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
470 JAK-STAT signaling pathway 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
471 JAK-STAT signaling pathway 💬
 [4] JAK1, JAK2, JAK3, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
472 JAK-STAT signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
473 JAK-STAT signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
474 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
475 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
476 Kaposi sarcoma-associated herpesvirus infection 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
477 Kaposi sarcoma-associated herpesvirus infection 💬
 [3] JAK1, JAK2, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
478 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
479 Kaposi sarcoma-associated herpesvirus infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
480 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
481 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
482 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
483 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
484 Legionellosis 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
485 Legionellosis 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
486 Legionellosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
487 Legionellosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
488 Leishmaniasis 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
489 Leishmaniasis 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
490 Leishmaniasis 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
491 Leishmaniasis 💬
 [2] JAK1, JAK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
492 Leishmaniasis 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
493 Leishmaniasis 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
494 Leishmaniasis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
495 Leukocyte transendothelial migration 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
496 Leukocyte transendothelial migration 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
497 Leukocyte transendothelial migration 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
498 Lipid and atherosclerosis 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
499 Lipid and atherosclerosis 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
500 Lipid and atherosclerosis 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
501 Lipid and atherosclerosis 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
502 Lipid and atherosclerosis 💬
 [1] JAK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
503 Lipid and atherosclerosis 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
504 Lipid and atherosclerosis 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
505 Lipid and atherosclerosis 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
506 Lipid and atherosclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
507 Lipid and atherosclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
508 Lipid and atherosclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
509 Lipid and atherosclerosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
510 Lipid and atherosclerosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
511 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
512 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
513 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
514 Longevity regulating pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
515 Longevity regulating pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
516 Longevity regulating pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
517 Longevity regulating pathway - multiple species 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
518 Longevity regulating pathway - multiple species 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
519 Malaria 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
520 Malaria 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
521 Malaria 💬
 [1] IL12A 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
522 Malaria 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
523 Malaria 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
524 Malaria 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
525 MAPK signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
526 MAPK signaling pathway 💬
 [1] NGFR 💬 D11028 💬 Cenegermin [2] 53, 90 💬
527 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
528 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
529 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
530 MAPK signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
531 MAPK signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
532 Measles 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
533 Measles 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
534 Measles 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
535 Measles 💬
 [3] JAK1, JAK3, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
536 Measles 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
537 Measles 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
538 Measles 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
539 Melanoma 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
540 Melanoma 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
541 Metabolic pathways 💬
 [2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
542 Metabolic pathways 💬
 [2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
543 Metabolic pathways 💬
 [1] DHODH 💬 D00749 💬 Leflunomide [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬
544 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D01392 💬 Mizoribine [8] 46, 49, 51, 53, 66, 94, 222, 224 💬
545 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
546 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D05094 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
547 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D05095 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
548 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [36]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
549 Metabolic pathways 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
550 Metabolic pathways 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
551 MicroRNAs in cancer 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
552 MicroRNAs in cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
553 MicroRNAs in cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
554 Mineral absorption 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [25]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
555 mTOR signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
556 mTOR signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
557 mTOR signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
558 mTOR signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
559 Natural killer cell mediated cytotoxicity 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
560 Natural killer cell mediated cytotoxicity 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
561 Natural killer cell mediated cytotoxicity 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
562 Natural killer cell mediated cytotoxicity 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
563 Natural killer cell mediated cytotoxicity 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
564 Natural killer cell mediated cytotoxicity 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
565 Natural killer cell mediated cytotoxicity 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
566 Natural killer cell mediated cytotoxicity 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
567 Necroptosis 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
568 Necroptosis 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
569 Necroptosis 💬
 [4] JAK1, JAK2, JAK3, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
570 Necroptosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
571 Necroptosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
572 Neuroactive ligand-receptor interaction 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
573 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
574 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
575 Neuroactive ligand-receptor interaction 💬
 [2] CHRM2, CHRM3 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
576 Neuroactive ligand-receptor interaction 💬
 [2] CHRM2, CHRM3 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
577 Neuroactive ligand-receptor interaction 💬
 [2] CHRM2, CHRM3 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
578 Neuroactive ligand-receptor interaction 💬
 [1] CHRM3 💬 D00661 💬 Cevimeline [1] 53 💬
579 Neuroactive ligand-receptor interaction 💬
 [1] CHRM3 💬 D07667 💬 Cevimeline [1] 53 💬
580 Neuroactive ligand-receptor interaction 💬
 [1] CHRM3 💬 D01269 💬 Solifenacin [3]  6 , 13, 53 💬
581 Neuroactive ligand-receptor interaction 💬
 [1] CHRM3 💬 D08522 💬 Solifenacin [3]  6 , 13, 53 💬
582 Neuroactive ligand-receptor interaction 💬
 [1] CHRM3 💬 D00646 💬 Tolterodine [2] 17, 53 💬
583 Neuroactive ligand-receptor interaction 💬
 [1] CHRM3 💬 D01148 💬 Tolterodine [2] 17, 53 💬
584 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00292 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
585 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00975 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
586 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01510 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
587 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01615 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
588 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01632 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
589 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D01948 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
590 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02174 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
591 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02591 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
592 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D02592 💬 Dexamethasone [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
593 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00088 💬 Hydrocortisone [11]  6 , 41, 46, 53, 75, 78, 81, 83, 97, 98, 299 💬
594 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D05000 💬 Methylprednisolone hemisuccinate [7] 13, 49, 50, 51, 53, 97, 211 💬
595 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 D00473 💬 Prednisone [48]  2 ,  6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬
596 Neurotrophin signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
597 Neurotrophin signaling pathway 💬
 [1] NGFR 💬 D11028 💬 Cenegermin [2] 53, 90 💬
598 Neurotrophin signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
599 Neurotrophin signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
600 Neutrophil extracellular trap formation 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
601 Neutrophil extracellular trap formation 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
602 Neutrophil extracellular trap formation 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
603 Neutrophil extracellular trap formation 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
604 NF-kappa B signaling pathway 💬
 [1] BTK 💬 D11478 💬 Branebrutinib [3] 46, 49, 53 💬
605 NF-kappa B signaling pathway 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
606 NF-kappa B signaling pathway 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
607 NF-kappa B signaling pathway 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
608 NF-kappa B signaling pathway 💬
 [1] LTB 💬 D08866 💬 Baminercept [4] 13, 46, 53, 97 💬
609 NF-kappa B signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
610 NF-kappa B signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
611 NF-kappa B signaling pathway 💬
 [1] TNFRSF13C 💬 D12151 💬 Ianalumab [5] 35, 46, 49, 53, 95 💬
612 NF-kappa B signaling pathway 💬
 [1] TNFSF13B 💬 D03068 💬 Belimumab [12] 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300 💬
613 NF-kappa B signaling pathway 💬
 [1] TNFSF13B 💬 D11127 💬 Tibulizumab [1] 53 💬
614 NOD-like receptor signaling pathway 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
615 NOD-like receptor signaling pathway 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
616 NOD-like receptor signaling pathway 💬
 [2] JAK1, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
617 NOD-like receptor signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
618 NOD-like receptor signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
619 NOD-like receptor signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
620 Non-alcoholic fatty liver disease 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
621 Non-alcoholic fatty liver disease 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
622 Non-alcoholic fatty liver disease 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
623 Non-alcoholic fatty liver disease 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
624 Non-alcoholic fatty liver disease 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
625 Non-alcoholic fatty liver disease 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
626 Non-small cell lung cancer 💬
 [1] JAK3 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
627 Non-small cell lung cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
628 Non-small cell lung cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
629 Non-small cell lung cancer 💬
 [1] RARB 💬 D06543 💬 Vitamin A [3] 13, 53, 90 💬
630 One carbon pool by folate 💬
 [2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
631 One carbon pool by folate 💬
 [2] DHFR, DHFR2 💬 D02115 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
632 Oocyte meiosis 💬
 [1] AR 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
633 Oocyte meiosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
634 Oocyte meiosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
635 Oocyte meiosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
636 Osteoclast differentiation 💬
 [1] BTK 💬 D11478 💬 Branebrutinib [3] 46, 49, 53 💬
637 Osteoclast differentiation 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
638 Osteoclast differentiation 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
639 Osteoclast differentiation 💬
 [2] JAK1, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
640 Osteoclast differentiation 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
641 Osteoclast differentiation 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
642 Osteoclast differentiation 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
643 Osteoclast differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
644 Osteoclast differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
645 Osteoclast differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
646 Osteoclast differentiation 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
647 Osteoclast differentiation 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
648 Oxytocin signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
649 Oxytocin signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
650 Oxytocin signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
651 Pancreatic cancer 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
652 Pancreatic cancer 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
653 Pancreatic cancer 💬
 [1] JAK1 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
654 Pancreatic cancer 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
655 Pancreatic cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
656 Pancreatic cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
657 Pancreatic secretion 💬
 [1] CHRM3 💬 D00661 💬 Cevimeline [1] 53 💬
658 Pancreatic secretion 💬
 [1] CHRM3 💬 D07667 💬 Cevimeline [1] 53 💬
659 Pancreatic secretion 💬
 [1] CHRM3 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
660 Pancreatic secretion 💬
 [1] CHRM3 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
661 Pancreatic secretion 💬
 [1] CHRM3 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
662 Pancreatic secretion 💬
 [1] CHRM3 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
663 Pancreatic secretion 💬
 [1] CHRM3 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
664 Pancreatic secretion 💬
 [1] CHRM3 💬 D01269 💬 Solifenacin [3]  6 , 13, 53 💬
665 Pancreatic secretion 💬
 [1] CHRM3 💬 D08522 💬 Solifenacin [3]  6 , 13, 53 💬
666 Pancreatic secretion 💬
 [1] CHRM3 💬 D00646 💬 Tolterodine [2] 17, 53 💬
667 Pancreatic secretion 💬
 [1] CHRM3 💬 D01148 💬 Tolterodine [2] 17, 53 💬
668 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [25]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
669 Pathogenic Escherichia coli infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
670 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
671 Pathogenic Escherichia coli infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
672 Pathways in cancer 💬
 [3] AR, ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
673 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D11513 💬 Estetrol [1] 53 💬
674 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 D11514 💬 Estetrol [1] 53 💬
675 Pathways in cancer 💬
 [3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
676 Pathways in cancer 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
677 Pathways in cancer 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
678 Pathways in cancer 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
679 Pathways in cancer 💬
 [3] JAK1, JAK2, JAK3 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
680 Pathways in cancer 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
681 Pathways in cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
682 Pathways in cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
683 Pathways in cancer 💬
 [2] RARA, RARB 💬 D06543 💬 Vitamin A [3] 13, 53, 90 💬
684 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
685 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
686 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 D00661 💬 Cevimeline [1] 53 💬
687 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 D07667 💬 Cevimeline [1] 53 💬
688 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
689 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
690 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
691 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 D01269 💬 Solifenacin [3]  6 , 13, 53 💬
692 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 D08522 💬 Solifenacin [3]  6 , 13, 53 💬
693 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 D00646 💬 Tolterodine [2] 17, 53 💬
694 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 D01148 💬 Tolterodine [2] 17, 53 💬
695 Pathways of neurodegeneration - multiple diseases 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
696 Pathways of neurodegeneration - multiple diseases 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
697 Pathways of neurodegeneration - multiple diseases 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
698 Pathways of neurodegeneration - multiple diseases 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
699 Pathways of neurodegeneration - multiple diseases 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
700 Pathways of neurodegeneration - multiple diseases 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
701 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
702 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
703 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [2] JAK1, JAK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
704 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
705 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] PDCD1 💬 D10316 💬 Nivolumab [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
706 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
707 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
708 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
709 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
710 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
711 Pertussis 💬
 [3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
712 Pertussis 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
713 Pertussis 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
714 Pertussis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
715 Phosphatidylinositol signaling system 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
716 Phosphatidylinositol signaling system 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
717 Phospholipase D signaling pathway 💬
 [1] FCER1A 💬 D05251 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
718 Phospholipase D signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
719 Phospholipase D signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
720 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
721 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
722 PI3K-Akt signaling pathway 💬
 [1] CHRM2 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
723 PI3K-Akt signaling pathway 💬
 [1] CHRM2 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
724 PI3K-Akt signaling pathway 💬
 [1] CHRM2 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
725 PI3K-Akt signaling pathway 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
726 PI3K-Akt signaling pathway 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
727 PI3K-Akt signaling pathway 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
728 PI3K-Akt signaling pathway 💬
 [3] JAK1, JAK2, JAK3 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
729 PI3K-Akt signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
730 PI3K-Akt signaling pathway 💬
 [1] NGFR 💬 D11028 💬 Cenegermin [2] 53, 90 💬
731 PI3K-Akt signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
732 PI3K-Akt signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
733 Platelet activation 💬
 [1] BTK 💬 D11478 💬 Branebrutinib [3] 46, 49, 53 💬
734 Platelet activation 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
735 Platelet activation 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
736 Platinum drug resistance 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
737 Platinum drug resistance 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
738 Primary immunodeficiency 💬
 [1] BTK 💬 D11478 💬 Branebrutinib [3] 46, 49, 53 💬
739 Primary immunodeficiency 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
740 Primary immunodeficiency 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
741 Primary immunodeficiency 💬
 [1] JAK3 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
742 Primary immunodeficiency 💬
 [1] TNFRSF13C 💬 D12151 💬 Ianalumab [5] 35, 46, 49, 53, 95 💬
743 Prion disease 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
744 Prion disease 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
745 Prion disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
746 Prion disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
747 Prion disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
748 Prion disease 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
749 Prion disease 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
750 Progesterone-mediated oocyte maturation 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
751 Progesterone-mediated oocyte maturation 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
752 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D11513 💬 Estetrol [1] 53 💬
753 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D11514 💬 Estetrol [1] 53 💬
754 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
755 Prolactin signaling pathway 💬
 [1] JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
756 Prolactin signaling pathway 💬
 [1] JAK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
757 Prolactin signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
758 Prolactin signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
759 Prolactin signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
760 Prostate cancer 💬
 [1] AR 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
761 Prostate cancer 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
762 Prostate cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
763 Prostate cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
764 Proteoglycans in cancer 💬
 [1] ESR1 💬 D11513 💬 Estetrol [1] 53 💬
765 Proteoglycans in cancer 💬
 [1] ESR1 💬 D11514 💬 Estetrol [1] 53 💬
766 Proteoglycans in cancer 💬
 [1] ESR1 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
767 Proteoglycans in cancer 💬
 [1] IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
768 Proteoglycans in cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
769 Proteoglycans in cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
770 Proteoglycans in cancer 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
771 Proteoglycans in cancer 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
772 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 D01392 💬 Mizoribine [8] 46, 49, 51, 53, 66, 94, 222, 224 💬
773 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
774 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 D05094 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
775 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 D05095 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
776 Purine metabolism 💬
 [2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [36]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
777 Pyrimidine metabolism 💬
 [1] DHODH 💬 D00749 💬 Leflunomide [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬
778 Rap1 signaling pathway 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
779 Rap1 signaling pathway 💬
 [1] NGFR 💬 D11028 💬 Cenegermin [2] 53, 90 💬
780 Rap1 signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
781 Rap1 signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
782 Ras signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
783 Ras signaling pathway 💬
 [1] NGFR 💬 D11028 💬 Cenegermin [2] 53, 90 💬
784 Ras signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
785 Ras signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
786 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
787 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
788 Regulation of actin cytoskeleton 💬
 [2] CHRM2, CHRM3 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
789 Regulation of actin cytoskeleton 💬
 [2] CHRM2, CHRM3 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
790 Regulation of actin cytoskeleton 💬
 [2] CHRM2, CHRM3 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
791 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 D00661 💬 Cevimeline [1] 53 💬
792 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 D07667 💬 Cevimeline [1] 53 💬
793 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 D01269 💬 Solifenacin [3]  6 , 13, 53 💬
794 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 D08522 💬 Solifenacin [3]  6 , 13, 53 💬
795 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 D00646 💬 Tolterodine [2] 17, 53 💬
796 Regulation of actin cytoskeleton 💬
 [1] CHRM3 💬 D01148 💬 Tolterodine [2] 17, 53 💬
797 Regulation of actin cytoskeleton 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
798 Regulation of actin cytoskeleton 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
799 Regulation of actin cytoskeleton 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
800 Regulation of lipolysis in adipocytes 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
801 Regulation of lipolysis in adipocytes 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
802 Regulation of lipolysis in adipocytes 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
803 Relaxin signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
804 Relaxin signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
805 Relaxin signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
806 Renal cell carcinoma 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
807 Renal cell carcinoma 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
808 Renin secretion 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
809 Renin secretion 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
810 Renin secretion 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
811 Renin secretion 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
812 Rheumatoid arthritis 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
813 Rheumatoid arthritis 💬
 [2] IL17A, TNFSF13B 💬 D11127 💬 Tibulizumab [1] 53 💬
814 Rheumatoid arthritis 💬
 [1] IL23A 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
815 Rheumatoid arthritis 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
816 Rheumatoid arthritis 💬
 [1] LTB 💬 D08866 💬 Baminercept [4] 13, 46, 53, 97 💬
817 Rheumatoid arthritis 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
818 Rheumatoid arthritis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
819 Rheumatoid arthritis 💬
 [1] TNFSF13B 💬 D03068 💬 Belimumab [12] 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300 💬
820 RIG-I-like receptor signaling pathway 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
821 RIG-I-like receptor signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
822 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
823 RIG-I-like receptor signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
824 Salivary secretion 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
825 Salivary secretion 💬
 [1] CHRM3 💬 D00661 💬 Cevimeline [1] 53 💬
826 Salivary secretion 💬
 [1] CHRM3 💬 D07667 💬 Cevimeline [1] 53 💬
827 Salivary secretion 💬
 [1] CHRM3 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
828 Salivary secretion 💬
 [1] CHRM3 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
829 Salivary secretion 💬
 [1] CHRM3 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
830 Salivary secretion 💬
 [1] CHRM3 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
831 Salivary secretion 💬
 [1] CHRM3 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
832 Salivary secretion 💬
 [1] CHRM3 💬 D01269 💬 Solifenacin [3]  6 , 13, 53 💬
833 Salivary secretion 💬
 [1] CHRM3 💬 D08522 💬 Solifenacin [3]  6 , 13, 53 💬
834 Salivary secretion 💬
 [1] CHRM3 💬 D00646 💬 Tolterodine [2] 17, 53 💬
835 Salivary secretion 💬
 [1] CHRM3 💬 D01148 💬 Tolterodine [2] 17, 53 💬
836 Salmonella infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
837 Salmonella infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
838 Salmonella infection 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
839 Salmonella infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
840 Salmonella infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
841 Shigellosis 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
842 Shigellosis 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
843 Shigellosis 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
844 Shigellosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
845 Shigellosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
846 Signaling pathways regulating pluripotency of stem cells 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
847 Signaling pathways regulating pluripotency of stem cells 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
848 Signaling pathways regulating pluripotency of stem cells 💬
 [3] JAK1, JAK2, JAK3 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
849 Signaling pathways regulating pluripotency of stem cells 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
850 Signaling pathways regulating pluripotency of stem cells 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
851 Small cell lung cancer 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
852 Small cell lung cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
853 Small cell lung cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
854 Small cell lung cancer 💬
 [1] RARB 💬 D06543 💬 Vitamin A [3] 13, 53, 90 💬
855 Sphingolipid signaling pathway 💬
 [1] FCER1A 💬 D05251 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
856 Sphingolipid signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
857 Sphingolipid signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
858 Sphingolipid signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
859 Sphingolipid signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
860 Sphingolipid signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
861 Spinocerebellar ataxia 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
862 Spinocerebellar ataxia 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
863 Staphylococcus aureus infection 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
864 Systemic lupus erythematosus 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
865 Systemic lupus erythematosus 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
866 Systemic lupus erythematosus 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
867 Systemic lupus erythematosus 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
868 Systemic lupus erythematosus 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
869 T cell receptor signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
870 T cell receptor signaling pathway 💬
 [1] PDCD1 💬 D10316 💬 Nivolumab [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
871 T cell receptor signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
872 T cell receptor signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
873 T cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
874 T cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
875 T cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
876 T cell receptor signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
877 T cell receptor signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
878 Taste transduction 💬
 [1] CHRM3 💬 D00661 💬 Cevimeline [1] 53 💬
879 Taste transduction 💬
 [1] CHRM3 💬 D07667 💬 Cevimeline [1] 53 💬
880 Taste transduction 💬
 [1] CHRM3 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
881 Taste transduction 💬
 [1] CHRM3 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
882 Taste transduction 💬
 [1] CHRM3 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
883 Taste transduction 💬
 [1] CHRM3 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
884 Taste transduction 💬
 [1] CHRM3 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
885 Taste transduction 💬
 [1] CHRM3 💬 D01269 💬 Solifenacin [3]  6 , 13, 53 💬
886 Taste transduction 💬
 [1] CHRM3 💬 D08522 💬 Solifenacin [3]  6 , 13, 53 💬
887 Taste transduction 💬
 [1] CHRM3 💬 D00646 💬 Tolterodine [2] 17, 53 💬
888 Taste transduction 💬
 [1] CHRM3 💬 D01148 💬 Tolterodine [2] 17, 53 💬
889 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 D01450 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
890 Taste transduction 💬
 [3] SCN2A, SCN3A, SCN9A 💬 D07552 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
891 TGF-beta signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
892 TGF-beta signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
893 Th1 and Th2 cell differentiation 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
894 Th1 and Th2 cell differentiation 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
895 Th1 and Th2 cell differentiation 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
896 Th1 and Th2 cell differentiation 💬
 [4] JAK1, JAK2, JAK3, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
897 Th1 and Th2 cell differentiation 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
898 Th1 and Th2 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
899 Th1 and Th2 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
900 Th1 and Th2 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
901 Th17 cell differentiation 💬
 [1] IL17A 💬 D11127 💬 Tibulizumab [1] 53 💬
902 Th17 cell differentiation 💬
 [1] IL23A 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
903 Th17 cell differentiation 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
904 Th17 cell differentiation 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
905 Th17 cell differentiation 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
906 Th17 cell differentiation 💬
 [4] JAK1, JAK2, JAK3, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
907 Th17 cell differentiation 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
908 Th17 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
909 Th17 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
910 Th17 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
911 Th17 cell differentiation 💬
 [1] RARA 💬 D06543 💬 Vitamin A [3] 13, 53, 90 💬
912 Thermogenesis 💬
 [1] ADRB3 💬 D09535 💬 Mirabegron [4]  6 , 13, 53, 226 💬
913 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D11513 💬 Estetrol [1] 53 💬
914 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D11514 💬 Estetrol [1] 53 💬
915 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
916 Thyroid hormone signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
917 Thyroid hormone signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
918 TNF signaling pathway 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
919 TNF signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
920 TNF signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
921 TNF signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
922 TNF signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
923 Toll-like receptor signaling pathway 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
924 Toll-like receptor signaling pathway 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
925 Toll-like receptor signaling pathway 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
926 Toll-like receptor signaling pathway 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
927 Toll-like receptor signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
928 Toll-like receptor signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
929 Toll-like receptor signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
930 Toll-like receptor signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
931 Toll-like receptor signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
932 Toxoplasmosis 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
933 Toxoplasmosis 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
934 Toxoplasmosis 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
935 Toxoplasmosis 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
936 Toxoplasmosis 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
937 Toxoplasmosis 💬
 [3] JAK1, JAK2, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
938 Toxoplasmosis 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
939 Toxoplasmosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
940 Toxoplasmosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
941 Transcriptional misregulation in cancer 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
942 Transcriptional misregulation in cancer 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
943 Transcriptional misregulation in cancer 💬
 [1] CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
944 Transcriptional misregulation in cancer 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
945 Transcriptional misregulation in cancer 💬
 [1] NGFR 💬 D11028 💬 Cenegermin [2] 53, 90 💬
946 Transcriptional misregulation in cancer 💬
 [1] RARA 💬 D06543 💬 Vitamin A [3] 13, 53, 90 💬
947 Tuberculosis 💬
 [3] IL12A, IL12B, IL23A 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
948 Tuberculosis 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
949 Tuberculosis 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
950 Tuberculosis 💬
 [2] JAK1, JAK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
951 Tuberculosis 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
952 Tuberculosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
953 Tuberculosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
954 Tuberculosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
955 Tuberculosis 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
956 Tuberculosis 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
957 Tuberculosis 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [25]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
958 Type I diabetes mellitus 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
959 Type I diabetes mellitus 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
960 Type I diabetes mellitus 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
961 Type I diabetes mellitus 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
962 Type II diabetes mellitus 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
963 Type II diabetes mellitus 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
964 Type II diabetes mellitus 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
965 Type II diabetes mellitus 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
966 VEGF signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
967 VEGF signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
968 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
969 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
970 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
971 Viral carcinogenesis 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
972 Viral carcinogenesis 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
973 Viral carcinogenesis 💬
 [2] JAK1, JAK3 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
974 Viral carcinogenesis 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
975 Viral carcinogenesis 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
976 Viral carcinogenesis 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
977 Viral myocarditis 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
978 Viral myocarditis 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
979 Viral myocarditis 💬
 [2] CD80, CD86 💬 D03203 💬 Abatacept [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
980 Viral myocarditis 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
981 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
982 Viral protein interaction with cytokine and cytokine receptor 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
983 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
984 Wnt signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
985 Wnt signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
986 Wnt signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
987 Yersinia infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
988 Yersinia infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
989 Yersinia infection 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
990 Yersinia infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
991 Yersinia infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬

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