Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Axon guidance 💬
[1] ABL1 💬 D01441 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
2 Axon guidance 💬
[1] ABL1 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
3 Axon guidance 💬
[1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
4 Axon guidance 💬
[4] ABL1, EPHA2, FYN, SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
5 Axon guidance 💬
[4] ABL1, EPHA2, FYN, SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
6 Axon guidance 💬
[2] ABL1, SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
7 Axon guidance 💬
[2] ABL1, SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
8 Axon guidance 💬
[1] BMPR2 💬 D03779 💬 Dibotermin alfa [1] 34 💬
9 Axon guidance 💬
[1] CXCR4 💬 D08971 💬 Plerixafor [6] 19, 20, 51, 65, 285, 299 💬
10 Axon guidance 💬
[1] EPHB4 💬 D11772 💬 Tesevatinib [1] 67 💬
11 Axon guidance 💬
[1] MET 💬 D10062 💬 Cabozantinib [1] 34 💬
12 Axon guidance 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
13 Axon guidance 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
14 Axon guidance 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
15 Axon guidance 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus [1] 160 💬
16 Axon guidance 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
17 Axon guidance 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
18 Axon guidance 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin [1] 222 💬
19 Axon guidance 💬
[1] RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
20 Axon guidance 💬
[1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
21 Axon guidance 💬
[1] RGMA 💬 D11355 💬 Elezanumab [1] 13 💬
22 Axon guidance 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
23 Axon guidance 💬
[1] ROCK2 💬 D11815 💬 Belumosudil [1] 51 💬
24 Axon guidance 💬
[1] SMO 💬 D10671 💬 Taladegib [1] 85 💬
25 Axon guidance 💬
[1] SMO 💬 D09992 💬 Vismodegib [1] 85 💬