Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Leukocyte transendothelial migration 💬
[1] CXCR4 💬 D08971 💬 Plerixafor [6] 19, 20, 51, 65, 285, 299 💬
2 Leukocyte transendothelial migration 💬
[1] ITGA4 💬 D10540 💬 Abrilumab [2] 96, 97 💬
3 Leukocyte transendothelial migration 💬
[1] ITGA4 💬 D06590 💬 Firategrast [1] 13 💬
4 Leukocyte transendothelial migration 💬
[1] ITGA4 💬 D06886 💬 Natalizumab [6] 13, 15, 25, 46, 63, 96 💬
5 Leukocyte transendothelial migration 💬
[1] ITGA4 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
6 Leukocyte transendothelial migration 💬
[1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
7 Leukocyte transendothelial migration 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
8 Leukocyte transendothelial migration 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
9 Leukocyte transendothelial migration 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
10 Leukocyte transendothelial migration 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
11 Leukocyte transendothelial migration 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
12 Leukocyte transendothelial migration 💬
[1] ROCK2 💬 D11815 💬 Belumosudil [1] 51 💬