Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D00355 Lansoprazole 7件: 63, 71, 85, 98, 166, 222, 299
2 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D00455 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
3 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D00724 Rabeprazole 2件: 2, 51
4 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D01207 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
5 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D01984 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
6 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D02593 Pantoprazole 2件: 13, 65
7 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D04056 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
8 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D05259 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
9 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D05261 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
10 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D05353 Pantoprazole 2件: 13, 65
11 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D07917 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
12 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D08463 Rabeprazole 2件: 2, 51
13 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D08903 Dexlansoprazole 1件: 98
14 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D09339 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
15 ATP4A 4件: Oxidative phosphorylation 💬, Metabolic pathways 💬, Collecting duct acid secretion 💬, Gastric acid secretion 💬 D11784 Vonoprazan 2件: 63, 98