Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 NF-kappa B signaling pathway 💬
1件: BCL2 💬 D10679 💬 Venetoclax 1件: 28 💬
2 NF-kappa B signaling pathway 💬
1件: BTK 💬 D10893 💬 Acalabrutinib 2件: 46, 61 💬
3 NF-kappa B signaling pathway 💬
1件: BTK 💬 D11478 💬 Branebrutinib 3件: 46, 49, 53 💬
4 NF-kappa B signaling pathway 💬
1件: BTK 💬 D11457 💬 Fenebrutinib 1件: 13 💬
5 NF-kappa B signaling pathway 💬
1件: BTK 💬 D10223 💬 Ibrutinib 3件: 28, 60, 61 💬
6 NF-kappa B signaling pathway 💬
1件: BTK 💬 D12160 💬 Orelabrutinib 3件: 13, 61, 63 💬
7 NF-kappa B signaling pathway 💬
1件: BTK 💬 D11422 💬 Zanubrutinib 2件: 300, 331 💬
8 NF-kappa B signaling pathway 💬
1件: CD40 💬 D11357 💬 Bleselumab 1件: 222 💬
9 NF-kappa B signaling pathway 💬
1件: CD40 💬 D11610 💬 Iscalimab 2件: 49, 53 💬
10 NF-kappa B signaling pathway 💬
1件: CD40 💬 D11597 💬 Ravagalimab 2件: 53, 97 💬
11 NF-kappa B signaling pathway 💬
1件: CD40LG 💬 D06193 💬 Toralizumab 1件: 63 💬
12 NF-kappa B signaling pathway 💬
1件: IL1B 💬 D09315 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
13 NF-kappa B signaling pathway 💬
1件: IL1B 💬 D09911 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
14 NF-kappa B signaling pathway 💬
1件: IL1B 💬 D06635 💬 Rilonacept 4件: 51, 106, 107, 266 💬
15 NF-kappa B signaling pathway 💬
2件: IL1B, TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
16 NF-kappa B signaling pathway 💬
1件: IL1R1 💬 D02934 💬 Anakinra 19件:  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
17 NF-kappa B signaling pathway 💬
1件: LCK 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
18 NF-kappa B signaling pathway 💬
1件: LCK 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
19 NF-kappa B signaling pathway 💬
1件: LTA 💬 D10187 💬 Pateclizumab 1件: 46 💬
20 NF-kappa B signaling pathway 💬
2件: LTA, TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
21 NF-kappa B signaling pathway 💬
1件: LTB 💬 D08866 💬 Baminercept 4件: 13, 46, 53, 97 💬
22 NF-kappa B signaling pathway 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
23 NF-kappa B signaling pathway 💬
1件: PARP1 💬 D09730 💬 Olaparib 2件: 86, 285 💬
24 NF-kappa B signaling pathway 💬
1件: PRKCQ 💬 D09671 💬 Sotrastaurin 1件: 97 💬
25 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D01545 💬 Aceclofenac 1件: 46 💬
26 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00217 💬 Acetaminophen 18件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
27 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 15件: 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬
28 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00567 💬 Celecoxib 10件:  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
29 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
30 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
31 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
32 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00130 💬 Diflunisal 1件: 28 💬
33 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00315 💬 Etodolac 1件: 46 💬
34 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D03710 💬 Etoricoxib 2件: 46, 271 💬
35 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00330 💬 Flurbiprofen 3件: 13, 21, 46 💬
36 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D01475 💬 Flurbiprofen 3件: 13, 21, 46 💬
37 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D02290 💬 Flurbiprofen 3件: 13, 21, 46 💬
38 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00126 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
39 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D01122 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
40 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D04490 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
41 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D06606 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
42 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00141 💬 Indomethacin 3件: 225, 271, 298 💬
43 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D01565 💬 Indomethacin 3件: 225, 271, 298 💬
44 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D02110 💬 Indomethacin 3件: 225, 271, 298 💬
45 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00132 💬 Ketoprofen 1件: 46 💬
46 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00813 💬 Ketorolac 2件: 70, 226 💬
47 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D08104 💬 Ketorolac 2件: 70, 226 💬
48 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D08149 💬 Loxoprofen 2件: 46, 271 💬
49 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D03714 💬 Lumiracoxib 1件: 46 💬
50 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00969 💬 Meloxicam 4件: 46, 49, 271, 296 💬
51 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00118 💬 Naproxen 4件: 13, 46, 107, 271 💬
52 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D01049 💬 Nimesulide 1件: 46 💬
53 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D03716 💬 Parecoxib 2件: 46, 271 💬
54 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00568 💬 Rofecoxib 1件: 46 💬
55 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00428 💬 Salsalate 1件:  5  💬
56 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D00120 💬 Sulindac 1件: 206 💬
57 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D01183 💬 Tolfenamic acid 1件:  5  💬
58 NF-kappa B signaling pathway 💬
1件: PTGS2 💬 D02709 💬 Valdecoxib 1件: 46 💬
59 NF-kappa B signaling pathway 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
60 NF-kappa B signaling pathway 💬
1件: SYK 💬 D09347 💬 Fostamatinib 4件: 46, 49, 61, 66 💬
61 NF-kappa B signaling pathway 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
62 NF-kappa B signaling pathway 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
63 NF-kappa B signaling pathway 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
64 NF-kappa B signaling pathway 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
65 NF-kappa B signaling pathway 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
66 NF-kappa B signaling pathway 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
67 NF-kappa B signaling pathway 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
68 NF-kappa B signaling pathway 💬
1件: TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
69 NF-kappa B signaling pathway 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
70 NF-kappa B signaling pathway 💬
1件: TNFRSF13C 💬 D12151 💬 Ianalumab 5件: 35, 46, 49, 53, 95 💬
71 NF-kappa B signaling pathway 💬
1件: TNFSF11 💬 D03684 💬 Denosumab 7件: 46, 50, 93, 95, 96, 274, 299 💬
72 NF-kappa B signaling pathway 💬
1件: TNFSF13B 💬 D09704 💬 Atacicept 4件: 13, 46, 49, 66 💬
73 NF-kappa B signaling pathway 💬
1件: TNFSF13B 💬 D03068 💬 Belimumab 12件: 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300 💬
74 NF-kappa B signaling pathway 💬
1件: TNFSF13B 💬 D10083 💬 Tabalumab 2件: 46, 49 💬
75 NF-kappa B signaling pathway 💬
1件: TNFSF13B 💬 D11127 💬 Tibulizumab 1件: 53 💬