Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 BTK 7件: NF-kappa B signaling pathway 💬, Osteoclast differentiation 💬, Platelet activation 💬, B cell receptor signaling pathway 💬, Fc epsilon RI signaling pathway 💬, Epstein-Barr virus infection 💬, Primary immunodeficiency 💬 D10223 Ibrutinib 3件: 28, 60, 61
2 BTK 7件: NF-kappa B signaling pathway 💬, Osteoclast differentiation 💬, Platelet activation 💬, B cell receptor signaling pathway 💬, Fc epsilon RI signaling pathway 💬, Epstein-Barr virus infection 💬, Primary immunodeficiency 💬 D10893 Acalabrutinib 2件: 46, 61
3 BTK 7件: NF-kappa B signaling pathway 💬, Osteoclast differentiation 💬, Platelet activation 💬, B cell receptor signaling pathway 💬, Fc epsilon RI signaling pathway 💬, Epstein-Barr virus infection 💬, Primary immunodeficiency 💬 D11422 Zanubrutinib 2件: 300, 331
4 BTK 7件: NF-kappa B signaling pathway 💬, Osteoclast differentiation 💬, Platelet activation 💬, B cell receptor signaling pathway 💬, Fc epsilon RI signaling pathway 💬, Epstein-Barr virus infection 💬, Primary immunodeficiency 💬 D11457 Fenebrutinib 1件: 13
5 BTK 7件: NF-kappa B signaling pathway 💬, Osteoclast differentiation 💬, Platelet activation 💬, B cell receptor signaling pathway 💬, Fc epsilon RI signaling pathway 💬, Epstein-Barr virus infection 💬, Primary immunodeficiency 💬 D11478 Branebrutinib 3件: 46, 49, 53
6 BTK 7件: NF-kappa B signaling pathway 💬, Osteoclast differentiation 💬, Platelet activation 💬, B cell receptor signaling pathway 💬, Fc epsilon RI signaling pathway 💬, Epstein-Barr virus infection 💬, Primary immunodeficiency 💬 D12160 Orelabrutinib 3件: 13, 61, 63