Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Type II diabetes mellitus 💬
2件: ABCC8, KCNJ11 💬 D00294 💬 Diazoxide 2件: 13, 193 💬
2 Type II diabetes mellitus 💬
2件: ABCC8, KCNJ11 💬 D00418 💬 Minoxidil 1件: 179 💬
3 Type II diabetes mellitus 💬
2件: ABCC8, KCNJ11 💬 D00594 💬 Repaglinide 3件:  6 , 21, 299 💬
4 Type II diabetes mellitus 💬
3件: CACNA1B, CACNA1C, CACNA1D 💬 D01173 💬 Cilnidipine 1件: 67 💬
5 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D00615 💬 Amlodipine 4件: 13, 51, 67, 298 💬
6 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D02914 💬 Amlodipine 4件: 13, 51, 67, 298 💬
7 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D07450 💬 Amlodipine 4件: 13, 51, 67, 298 💬
8 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D00616 💬 Diltiazem 3件: 51, 58, 86 💬
9 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D03830 💬 Diltiazem 3件: 51, 58, 86 💬
10 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D07845 💬 Diltiazem 3件: 51, 58, 86 💬
11 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D00349 💬 Isradipine 1件:  6  💬
12 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D00617 💬 Nicardipine 2件: 70, 86 💬
13 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D08270 💬 Nicardipine 2件: 70, 86 💬
14 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D00437 💬 Nifedipine 2件: 50, 81 💬
15 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D01908 💬 Nilvadipine 1件: 90 💬
16 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D05442 💬 Perhexiline 2件: 58, 272 💬
17 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D08340 💬 Perhexiline 2件: 58, 272 💬
18 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D08441 💬 Propiverine 1件: 226 💬
19 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
20 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D00619 💬 Verapamil 3件: 96, 140, 167 💬
21 Type II diabetes mellitus 💬
2件: CACNA1C, CACNA1D 💬 D02356 💬 Verapamil 3件: 96, 140, 167 💬
22 Type II diabetes mellitus 💬
1件: CACNA1G 💬 D01303 💬 Flunarizine 4件: 58, 86, 149, 215 💬
23 Type II diabetes mellitus 💬
1件: CACNA1G 💬 D07971 💬 Flunarizine 4件: 58, 86, 149, 215 💬
24 Type II diabetes mellitus 💬
1件: CACNA1G 💬 D00399 💬 Valproic acid 17件:  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
25 Type II diabetes mellitus 💬
1件: CACNA1G 💬 D00538 💬 Zonisamide 1件:  6  💬
26 Type II diabetes mellitus 💬
1件: INSR 💬 D04539 💬 Insulin detemir 1件: 299 💬
27 Type II diabetes mellitus 💬
1件: INSR 💬 D03250 💬 Insulin glargine 1件: 299 💬
28 Type II diabetes mellitus 💬
1件: INSR 💬 D00085 💬 Insulin human 2件: 96, 156 💬
29 Type II diabetes mellitus 💬
1件: INSR 💬 D03230 💬 Insulin human 2件: 96, 156 💬
30 Type II diabetes mellitus 💬
1件: KCNJ11 💬 D00636 💬 Amiodarone 2件: 28, 127 💬
31 Type II diabetes mellitus 💬
1件: KCNJ11 💬 D02910 💬 Amiodarone 2件: 28, 127 💬
32 Type II diabetes mellitus 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
33 Type II diabetes mellitus 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
34 Type II diabetes mellitus 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
35 Type II diabetes mellitus 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
36 Type II diabetes mellitus 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
37 Type II diabetes mellitus 💬
2件: PRKCD, PRKCE 💬 D09671 💬 Sotrastaurin 1件: 97 💬
38 Type II diabetes mellitus 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
39 Type II diabetes mellitus 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
40 Type II diabetes mellitus 💬
1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
41 Type II diabetes mellitus 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
42 Type II diabetes mellitus 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
43 Type II diabetes mellitus 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
44 Type II diabetes mellitus 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
45 Type II diabetes mellitus 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
46 Type II diabetes mellitus 💬
1件: TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
47 Type II diabetes mellitus 💬
1件: TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
48 Type II diabetes mellitus 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬