Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 PIK3CD 106件: Inositol phosphate metabolism 💬, Metabolic pathways 💬, EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, Platinum drug resistance 💬, ErbB signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Chemokine signaling pathway 💬, HIF-1 signaling pathway 💬, FoxO signaling pathway 💬, Phosphatidylinositol signaling system 💬, Sphingolipid signaling pathway 💬, Phospholipase D signaling pathway 💬, Autophagy - animal 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Apoptosis 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Cellular senescence 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, Focal adhesion 💬, Signaling pathways regulating pluripotency of stem cells 💬, Platelet activation 💬, Neutrophil extracellular trap formation 💬, Toll-like receptor signaling pathway 💬, C-type lectin receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Fc epsilon RI signaling pathway 💬, Fc gamma R-mediated phagocytosis 💬, TNF signaling pathway 💬, Leukocyte transendothelial migration 💬, Neurotrophin signaling pathway 💬, Cholinergic synapse 💬, Inflammatory mediator regulation of TRP channels 💬, Regulation of actin cytoskeleton 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Relaxin signaling pathway 💬, GnRH secretion 💬, Type II diabetes mellitus 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Growth hormone synthesis, secretion and action 💬, Aldosterone-regulated sodium reabsorption 💬, Carbohydrate digestion and absorption 💬, Alzheimer disease 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Bacterial invasion of epithelial cells 💬, Shigellosis 💬, Salmonella infection 💬, Yersinia infection 💬, Chagas disease 💬, Amoebiasis 💬, Hepatitis C 💬, Hepatitis B 💬, Measles 💬, Human cytomegalovirus infection 💬, Influenza A 💬, Human papillomavirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Epstein-Barr virus infection 💬, Human immunodeficiency virus 1 infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Viral carcinogenesis 💬, Proteoglycans in cancer 💬, MicroRNAs in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Chemical carcinogenesis - reactive oxygen species 💬, Colorectal cancer 💬, Renal cell carcinoma 💬, Pancreatic cancer 💬, Endometrial cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Chronic myeloid leukemia 💬, Acute myeloid leukemia 💬, Small cell lung cancer 💬, Non-small cell lung cancer 💬, Breast cancer 💬, Hepatocellular carcinoma 💬, Gastric cancer 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Diabetic cardiomyopathy 💬, Lipid and atherosclerosis 💬, Fluid shear stress and atherosclerosis 💬 D11158 Leniolisib 2件: 53, 65
2 PIK3CD 106件: Inositol phosphate metabolism 💬, Metabolic pathways 💬, EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, Platinum drug resistance 💬, ErbB signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, cAMP signaling pathway 💬, Chemokine signaling pathway 💬, HIF-1 signaling pathway 💬, FoxO signaling pathway 💬, Phosphatidylinositol signaling system 💬, Sphingolipid signaling pathway 💬, Phospholipase D signaling pathway 💬, Autophagy - animal 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Apoptosis 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Cellular senescence 💬, Axon guidance 💬, VEGF signaling pathway 💬, Osteoclast differentiation 💬, Focal adhesion 💬, Signaling pathways regulating pluripotency of stem cells 💬, Platelet activation 💬, Neutrophil extracellular trap formation 💬, Toll-like receptor signaling pathway 💬, C-type lectin receptor signaling pathway 💬, JAK-STAT signaling pathway 💬, Natural killer cell mediated cytotoxicity 💬, T cell receptor signaling pathway 💬, B cell receptor signaling pathway 💬, Fc epsilon RI signaling pathway 💬, Fc gamma R-mediated phagocytosis 💬, TNF signaling pathway 💬, Leukocyte transendothelial migration 💬, Neurotrophin signaling pathway 💬, Cholinergic synapse 💬, Inflammatory mediator regulation of TRP channels 💬, Regulation of actin cytoskeleton 💬, Insulin signaling pathway 💬, Progesterone-mediated oocyte maturation 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Regulation of lipolysis in adipocytes 💬, Relaxin signaling pathway 💬, GnRH secretion 💬, Type II diabetes mellitus 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, AGE-RAGE signaling pathway in diabetic complications 💬, Growth hormone synthesis, secretion and action 💬, Aldosterone-regulated sodium reabsorption 💬, Carbohydrate digestion and absorption 💬, Alzheimer disease 💬, Spinocerebellar ataxia 💬, Prion disease 💬, Bacterial invasion of epithelial cells 💬, Shigellosis 💬, Salmonella infection 💬, Yersinia infection 💬, Chagas disease 💬, Amoebiasis 💬, Hepatitis C 💬, Hepatitis B 💬, Measles 💬, Human cytomegalovirus infection 💬, Influenza A 💬, Human papillomavirus infection 💬, Human T-cell leukemia virus 1 infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Epstein-Barr virus infection 💬, Human immunodeficiency virus 1 infection 💬, Coronavirus disease - COVID-19 💬, Pathways in cancer 💬, Viral carcinogenesis 💬, Proteoglycans in cancer 💬, MicroRNAs in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Chemical carcinogenesis - reactive oxygen species 💬, Colorectal cancer 💬, Renal cell carcinoma 💬, Pancreatic cancer 💬, Endometrial cancer 💬, Glioma 💬, Prostate cancer 💬, Melanoma 💬, Chronic myeloid leukemia 💬, Acute myeloid leukemia 💬, Small cell lung cancer 💬, Non-small cell lung cancer 💬, Breast cancer 💬, Hepatocellular carcinoma 💬, Gastric cancer 💬, Central carbon metabolism in cancer 💬, Choline metabolism in cancer 💬, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬, Diabetic cardiomyopathy 💬, Lipid and atherosclerosis 💬, Fluid shear stress and atherosclerosis 💬 D11437 Parsaclisib 3件: 35, 53, 61