Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 INSR 22件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, cGMP-PKG signaling pathway 💬, HIF-1 signaling pathway 💬, FoxO signaling pathway 💬, Phospholipase D signaling pathway 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Adherens junction 💬, Insulin signaling pathway 💬, Ovarian steroidogenesis 💬, Regulation of lipolysis in adipocytes 💬, Type II diabetes mellitus 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, Aldosterone-regulated sodium reabsorption 💬, Alzheimer disease 💬, Diabetic cardiomyopathy 💬 D00085 Insulin human 2件: 96, 156
2 INSR 22件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, cGMP-PKG signaling pathway 💬, HIF-1 signaling pathway 💬, FoxO signaling pathway 💬, Phospholipase D signaling pathway 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Adherens junction 💬, Insulin signaling pathway 💬, Ovarian steroidogenesis 💬, Regulation of lipolysis in adipocytes 💬, Type II diabetes mellitus 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, Aldosterone-regulated sodium reabsorption 💬, Alzheimer disease 💬, Diabetic cardiomyopathy 💬 D03230 Insulin human 2件: 96, 156
3 INSR 22件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, cGMP-PKG signaling pathway 💬, HIF-1 signaling pathway 💬, FoxO signaling pathway 💬, Phospholipase D signaling pathway 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Adherens junction 💬, Insulin signaling pathway 💬, Ovarian steroidogenesis 💬, Regulation of lipolysis in adipocytes 💬, Type II diabetes mellitus 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, Aldosterone-regulated sodium reabsorption 💬, Alzheimer disease 💬, Diabetic cardiomyopathy 💬 D03250 Insulin glargine 1件: 299
4 INSR 22件: MAPK signaling pathway 💬, Ras signaling pathway 💬, Rap1 signaling pathway 💬, cGMP-PKG signaling pathway 💬, HIF-1 signaling pathway 💬, FoxO signaling pathway 💬, Phospholipase D signaling pathway 💬, mTOR signaling pathway 💬, PI3K-Akt signaling pathway 💬, AMPK signaling pathway 💬, Longevity regulating pathway 💬, Longevity regulating pathway - multiple species 💬, Adherens junction 💬, Insulin signaling pathway 💬, Ovarian steroidogenesis 💬, Regulation of lipolysis in adipocytes 💬, Type II diabetes mellitus 💬, Insulin resistance 💬, Non-alcoholic fatty liver disease 💬, Aldosterone-regulated sodium reabsorption 💬, Alzheimer disease 💬, Diabetic cardiomyopathy 💬 D04539 Insulin detemir 1件: 299