Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Platelet activation 💬
1件: BTK 💬 Acalabrutinib 💬 Acalabrutinib 2件: 46, 61 💬
2 Platelet activation 💬
1件: BTK 💬 Branebrutinib 💬 Branebrutinib 3件: 46, 49, 53 💬
3 Platelet activation 💬
1件: BTK 💬 Evobrutinib 💬 Evobrutinib 3件: 13, 46, 49 💬
4 Platelet activation 💬
1件: BTK 💬 Fenebrutinib 💬 Fenebrutinib 1件: 13 💬
5 Platelet activation 💬
1件: BTK 💬 Ibrutinib 💬 Ibrutinib 3件: 28, 60, 61 💬
6 Platelet activation 💬
1件: BTK 💬 Orelabrutinib 💬 Orelabrutinib 4件: 13, 49, 61, 63 💬
7 Platelet activation 💬
1件: BTK 💬 Remibrutinib 💬 Remibrutinib 2件: 13, 53 💬
8 Platelet activation 💬
1件: BTK 💬 Zanubrutinib 💬 Zanubrutinib 5件: 13, 63, 222, 300, 331 💬
9 Platelet activation 💬
1件: F2 💬 Dabigatran 💬 Dabigatran 5件: 51, 75, 85, 91, 124 💬
10 Platelet activation 💬
1件: F2 💬 Dabigatran etexilate 💬 Dabigatran etexilate 2件: 51, 75 💬
11 Platelet activation 💬
1件: F2 💬 Thrombomodulin alfa 💬 Thrombomodulin Alfa 1件: 85 💬
12 Platelet activation 💬
2件: FYN, SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
13 Platelet activation 💬
2件: FYN, SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
14 Platelet activation 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 Amyl nitrite 💬 Amyl Nitrite 1件: 58 💬
15 Platelet activation 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬
16 Platelet activation 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
17 Platelet activation 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
18 Platelet activation 💬
1件: P2RY12 💬 Clopidogrel 💬 Clopidogrel 3件: 49, 51, 86 💬
19 Platelet activation 💬
1件: P2RY12 💬 Clopidogrel hydrochloride 💬 Clopidogrel 3件: 49, 51, 86 💬
20 Platelet activation 💬
1件: P2RY12 💬 Clopidogrel besilate 💬 Clopidogrel 3件: 49, 51, 86 💬
21 Platelet activation 💬
1件: P2RY12 💬 Ticagrelor 💬 Ticagrelor 3件: 36, 46, 85 💬
22 Platelet activation 💬
1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬
23 Platelet activation 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
24 Platelet activation 💬
1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
25 Platelet activation 💬
1件: PTGIR 💬 Beraprost 💬 Beraprost 1件: 86 💬
26 Platelet activation 💬
1件: PTGIR 💬 Epoprostenol 💬 Epoprostenol 1件: 86 💬
27 Platelet activation 💬
1件: PTGIR 💬 Ibudilast 💬 Ibudilast 2件:  2 , 13 💬
28 Platelet activation 💬
1件: PTGIR 💬 Iloprost 💬 Iloprost 4件: 51, 84, 85, 86 💬
29 Platelet activation 💬
1件: PTGIR 💬 Ralinepag 💬 Ralinepag 1件: 86 💬
30 Platelet activation 💬
1件: PTGIR 💬 Selexipag 💬 Selexipag 5件: 51, 70, 84, 86, 88 💬
31 Platelet activation 💬
1件: PTGIR 💬 Treprostinil 💬 Treprostinil 6件: 51, 84, 85, 86, 88, 210 💬
32 Platelet activation 💬
1件: PTGS1 💬 Aceclofenac 💬 Aceclofenac 1件: 46 💬
33 Platelet activation 💬
1件: PTGS1 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
34 Platelet activation 💬
1件: PTGS1 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
35 Platelet activation 💬
1件: PTGS1 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
36 Platelet activation 💬
1件: PTGS1 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬
37 Platelet activation 💬
1件: PTGS1 💬 Ibuprofen 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
38 Platelet activation 💬
1件: PTGS1 💬 Indomethacin 💬 Indomethacin 3件: 225, 271, 298 💬
39 Platelet activation 💬
1件: PTGS1 💬 Ketoprofen 💬 Ketoprofen 1件: 46 💬
40 Platelet activation 💬
1件: PTGS1 💬 Ketorolac 💬 Ketorolac 2件: 70, 226 💬
41 Platelet activation 💬
1件: PTGS1 💬 Loxoprofen 💬 Loxoprofen 2件: 46, 271 💬
42 Platelet activation 💬
1件: PTGS1 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬
43 Platelet activation 💬
1件: PTGS1 💬 Salsalate 💬 Salsalate 1件:  5  💬
44 Platelet activation 💬
1件: PTGS1 💬 Sulindac 💬 Sulindac 1件: 206 💬
45 Platelet activation 💬
1件: PTGS1 💬 Tolfenamic acid 💬 Tolfenamic acid 1件:  5  💬
46 Platelet activation 💬
2件: ROCK1, ROCK2 💬 Fasudil 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
47 Platelet activation 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 2件: 51, 85 💬
48 Platelet activation 💬
1件: SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬
49 Platelet activation 💬
1件: SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬
50 Platelet activation 💬
1件: SYK 💬 Fostamatinib 💬 Fostamatinib 4件: 46, 49, 61, 66 💬
51 Platelet activation 💬
1件: TBXA2R 💬 Cilostazol 💬 Cilostazol 3件: 46, 51, 70 💬
52 Platelet activation 💬
1件: TBXA2R 💬 Ifetroban 💬 Ifetroban 2件: 85, 113 💬
53 Platelet activation 💬
1件: TBXA2R 💬 Ramatroban 💬 Ramatroban 1件: 13 💬
54 Platelet activation 💬
1件: VWF 💬 Caplacizumab 💬 Caplacizumab 1件: 64 💬