Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Leishmaniasis 💬
 1件: C3 💬 Pegcetacoplan 💬 Pegcetacoplan 4件:  2 , 61, 62, 222 💬 💬
2 Leishmaniasis 💬
 1件: IFNG 💬 Emapalumab 💬 Emapalumab 3件: 49, 65, 107 💬 💬
3 Leishmaniasis 💬
 1件: IFNG 💬 Fontolizumab 💬 Fontolizumab 1件: 46 💬 💬
4 Leishmaniasis 💬
 2件: IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326 💬 💬
5 Leishmaniasis 💬
 4件: IL10, IL1A, IL1B, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
6 Leishmaniasis 💬
 2件: IL12A, IL12B 💬 Ustekinumab 💬 Ustekinumab 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬
7 Leishmaniasis 💬
 1件: IL1A 💬 Bermekimab 💬 Bermekimab 1件: 51 💬 💬
8 Leishmaniasis 💬
 2件: IL1A, IL1B 💬 Rilonacept 💬 Rilonacept 4件: 51, 106, 107, 266 💬 💬
9 Leishmaniasis 💬
 1件: IL1B 💬 Canakinumab 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬
10 Leishmaniasis 💬
 1件: IL1B 💬 Gevokizumab 💬 Gevokizumab 4件: 41, 50, 56, 269 💬 💬
11 Leishmaniasis 💬
 1件: IL4 💬 Binetrakin 💬 Binetrakin 1件: 46 💬 💬
12 Leishmaniasis 💬
 1件: ITGA4 💬 Abrilumab 💬 Abrilumab 2件: 96, 97 💬 💬
13 Leishmaniasis 💬
 1件: ITGA4 💬 Firategrast 💬 Firategrast 1件: 13 💬 💬
14 Leishmaniasis 💬
 1件: ITGA4 💬 Natalizumab 💬 Natalizumab 6件: 13, 15, 25, 46, 63, 96 💬 💬
15 Leishmaniasis 💬
 1件: ITGA4 💬 Vedolizumab 💬 Vedolizumab 3件: 94, 96, 97 💬 💬
16 Leishmaniasis 💬
 1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 1件: 84 💬 💬
17 Leishmaniasis 💬
 1件: JAK1 💬 Filgotinib 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬 💬
18 Leishmaniasis 💬
 1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬 💬
19 Leishmaniasis 💬
 1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 💬
20 Leishmaniasis 💬
 2件: JAK1, JAK2 💬 Baricitinib 💬 Baricitinib 13件:  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬
21 Leishmaniasis 💬
 2件: JAK1, JAK2 💬 Peficitinib 💬 Peficitinib 1件: 46 💬 💬
22 Leishmaniasis 💬
 2件: JAK1, JAK2 💬 Ruxolitinib 💬 Ruxolitinib 3件: 60, 65, 228 💬 💬
23 Leishmaniasis 💬
 2件: JAK1, JAK2 💬 Tofacitinib 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬
24 Leishmaniasis 💬
 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬 💬
25 Leishmaniasis 💬
 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬 💬
26 Leishmaniasis 💬
 1件: NFKB1 💬 Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬 💬
27 Leishmaniasis 💬
 1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬 💬
28 Leishmaniasis 💬
 1件: PTGS2 💬 Aceclofenac 💬 Aceclofenac 1件: 46 💬 💬
29 Leishmaniasis 💬
 1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
30 Leishmaniasis 💬
 1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
31 Leishmaniasis 💬
 1件: PTGS2 💬 Celecoxib 💬 Celecoxib 10件:  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬
32 Leishmaniasis 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
33 Leishmaniasis 💬
 1件: PTGS2 💬 Diflunisal 💬 Diflunisal 1件: 28 💬 💬
34 Leishmaniasis 💬
 1件: PTGS2 💬 Etodolac 💬 Etodolac 1件: 46 💬 💬
35 Leishmaniasis 💬
 1件: PTGS2 💬 Etoricoxib 💬 Etoricoxib 2件: 46, 271 💬 💬
36 Leishmaniasis 💬
 1件: PTGS2 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬 💬
37 Leishmaniasis 💬
 1件: PTGS2 💬 Ibuprofen 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬 💬
38 Leishmaniasis 💬
 1件: PTGS2 💬 Indomethacin 💬 Indomethacin 3件: 225, 271, 298 💬 💬
39 Leishmaniasis 💬
 1件: PTGS2 💬 Ketoprofen 💬 Ketoprofen 1件: 46 💬 💬
40 Leishmaniasis 💬
 1件: PTGS2 💬 Ketorolac 💬 Ketorolac 2件: 70, 226 💬 💬
41 Leishmaniasis 💬
 1件: PTGS2 💬 Loxoprofen 💬 Loxoprofen 2件: 46, 271 💬 💬
42 Leishmaniasis 💬
 1件: PTGS2 💬 Lumiracoxib 💬 Lumiracoxib 1件: 46 💬 💬
43 Leishmaniasis 💬
 1件: PTGS2 💬 Meloxicam 💬 Meloxicam 4件: 46, 49, 271, 296 💬 💬
44 Leishmaniasis 💬
 1件: PTGS2 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬 💬
45 Leishmaniasis 💬
 1件: PTGS2 💬 Nimesulide 💬 Nimesulide 1件: 46 💬 💬
46 Leishmaniasis 💬
 1件: PTGS2 💬 Parecoxib 💬 Parecoxib 2件: 46, 271 💬 💬
47 Leishmaniasis 💬
 1件: PTGS2 💬 Rofecoxib 💬 Rofecoxib 1件: 46 💬 💬
48 Leishmaniasis 💬
 1件: PTGS2 💬 Salsalate 💬 Salsalate 1件:  5  💬 💬
49 Leishmaniasis 💬
 1件: PTGS2 💬 Sulindac 💬 Sulindac 1件: 206 💬 💬
50 Leishmaniasis 💬
 1件: PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid 1件:  5  💬 💬
51 Leishmaniasis 💬
 1件: PTGS2 💬 Valdecoxib 💬 Valdecoxib 1件: 46 💬 💬
52 Leishmaniasis 💬
 1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬 💬
53 Leishmaniasis 💬
 3件: TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab 3件: 51, 85, 222 💬 💬
54 Leishmaniasis 💬
 1件: TNF 💬 Adalimumab 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬
55 Leishmaniasis 💬
 1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 💬
56 Leishmaniasis 💬
 1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬
57 Leishmaniasis 💬
 1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬
58 Leishmaniasis 💬
 1件: TNF 💬 Infliximab 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬
59 Leishmaniasis 💬
 1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 💬
60 Leishmaniasis 💬
 1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬 💬
61 Leishmaniasis 💬
 1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬 💬
62 Leishmaniasis 💬
 1件: TNF 💬 Pomalidomide 💬 Pomalidomide 5件: 28, 51, 85, 227, 331 💬 💬
63 Leishmaniasis 💬
 1件: TNF 💬 Thalidomide 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬