Drug Description in Trials / DrugBank / KEGG DRUG /

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(S)-4,5-dihydro-2-[2-hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazo----[1] 284 💬
2(S)-4,5-dihydro-2-[2-hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylate magnesium hydroxide[3] Hydroxide ion,
Magnesium,
Magnesium hydroxide		[1] Magnesium hydroxide 💬--[1] 284 💬
3(S)-4,5-dihydro-2[hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-m----[1] 284 💬
4(S)-4,5-dihydro-2[hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylate magnesium hydroxide[3] Hydroxide ion,
Magnesium,
Magnesium hydroxide		[1] Magnesium hydroxide 💬--[1] 284 💬
5Abatacept[1] Abatacept[1] Abatacept 💬[2] CD80,
CD86 💬		[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
6Alefacept[1] Alefacept[1] Alefacept 💬[1] CD58 💬[2] Cell adhesion molecules, Epstein-Barr virus infection 💬[6] 37, 60, 65, 164, 284, 285 💬
7ALEMTUZUMAB[1] Alemtuzumab[1] Alemtuzumab 💬[1] CD52 💬-[17] 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 164, 283, 284 💬
8Alpha beta depletion----[2] 60, 284 💬
9Anti-Thymocyte Globulin----[18] 11, 13, 14, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 164, 283, 284, 285 💬
10Antithymocyte Globulin----[2] 60, 284 💬
11BPX-501 T cells----[4] 65, 284, 285, 326 💬
12Busulfan[1] Busulfan[1] Busulfan 💬--[13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
13Busulfan, Cyclophosphamide, ATG, GCSF[2] Busulfan,
Cyclophosphamide		[3] Busulfan ,
Cyclophosphamide ,
Cyclophosphamide 💬		--[2] 65, 284 💬
14Busulfan, Fludarabine, ATG, TLI[2] Busulfan,
Fludarabine		[2] Busulfan ,
Fludarabine 💬		[1] RRM1 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[2] 65, 284 💬
15Campath, Fludarabine, Cyclophosphamide[2] Cyclophosphamide,
Fludarabine		[3] Cyclophosphamide ,
Cyclophosphamide ,
Fludarabine 💬		[1] RRM1 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[2] 65, 284 💬
16CD3/CD19 depleted leukocytes----[1] 284 💬
17CD34 Stem Cell Selection Therapy----[3] 60, 65, 284 💬
18CD45RA depleted leukocytes----[1] 284 💬
19Cyclophosphamide[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬		--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
20Cyclophosphamide Dose Level 1[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬		--[2] 65, 284 💬
21Cyclophosphamide Dose Level 2[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬		--[2] 65, 284 💬
22Cyclophosphamide Dose Level 3[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬		--[2] 65, 284 💬
23Cyclophosphamide Dose Level 4[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬		--[2] 65, 284 💬
24Cyclosporine[1] Cyclosporine[1] Cyclosporine 💬[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302 💬
25DACLIZUMAB[1] Daclizumab[1] Daclizumab 💬[1] IL2RA 💬[11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[8] 13, 56, 60, 65, 97, 107, 283, 284 💬
26Deferasirox[1] Deferasirox[1] Deferasirox 💬--[3] 254, 284, 286 💬
27Deferitazole[1] Deferitazole[1] Deferitazole 💬--[1] 284 💬
28Deferoxamine[1] Deferoxamine[1] Deferoxamine 💬--[2] 284, 286 💬
29Desferal[1] Deferoxamine[1] Deferoxamine 💬--[2] 284, 286 💬
30DFO----[3] 46, 284, 286 💬
31ELTROMBOPAG[1] Eltrombopag---[5] 60, 63, 65, 284, 285 💬
32Enriched Hematopoetic Stem Cell Infusion----[2] 19, 284 💬
33Exjade[1] Deferasirox[1] Deferasirox 💬--[3] 254, 284, 286 💬
34FBS0701----[1] 284 💬
35FBS0701 CAPSULE----[1] 284 💬
36FBS0701/SSP004184----[1] 284 💬
37Filgrastim[1] Filgrastim[1] Filgrastim 💬[1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[28] 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
38Fludarabine[1] Fludarabine[1] Fludarabine 💬[1] RRM1 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[19] 11, 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
39Fludarabine monophosphate[1] Fludarabine[1] Fludarabine 💬[1] RRM1 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[3] 65, 284, 326 💬
40Fludarabine phosphate[2] Fludarabine,
Phosphate ion		[1] Fludarabine 💬[1] RRM1 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[12] 28, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286 💬
41G-CSF[1] Filgrastim[1] Filgrastim 💬[1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[16] 2, 6, 11, 13, 16, 22, 47, 51, 60, 62, 65, 85, 96, 284, 285, 331 💬
42Human Placental Derived Stem Cell----[4] 19, 20, 60, 284 💬
43Hydroxide[1] Hydroxide ion---[5] 11, 46, 96, 97, 284 💬
44Hydroxyurea[1] Hydroxyurea[1] Hydroxyurea 💬[1] RRM2 💬[7] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[8] 3, 13, 19, 20, 65, 85, 86, 284 💬
45ICL670----[3] 60, 284, 286 💬
46Iron[1] Iron---[6] 18, 96, 97, 238, 254, 284 💬
47IRON CHELATING AGENTS[1] Iron---[1] 284 💬
48L-leucine[1] Leucine[1] Leucine 💬--[1] 284 💬
49Lenalidomide[1] Lenalidomide[1] Lenalidomide 💬[1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[8] 16, 26, 28, 34, 49, 284, 300, 331 💬
50Leucine[1] Leucine[1] Leucine 💬--[6] 6, 19, 65, 283, 284, 299 💬
51Magnesium[1] Magnesium---[15] 6, 11, 46, 64, 70, 93, 97, 166, 225, 235, 284, 291, 296, 297, 298 💬
52Magnesium hydroxide[3] Hydroxide ion,
Magnesium,
Magnesium hydroxide		[1] Magnesium hydroxide 💬--[1] 284 💬
53Melphalan[1] Melphalan[1] Melphalan 💬--[15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299 💬
54Mesenchymal Stromal Cells[1] Human Umbilical Cord Mesenchymal Stem Cells---[10] 2, 36, 49, 51, 60, 96, 97, 107, 274, 284 💬
55Methotrexate[1] Methotrexate[1] Methotrexate 💬[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
56Methylprednisolone[1] Methylprednisolone[1] Methylprednisolone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
57Mycophenolate[1] Mycophenolic acid[1] Mycophenolic acid 💬[2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
58Mycophenolate mofetil[2] Mycophenolate mofetil,
Mycophenolic acid		[2] Mycophenolate mofetil ,
Mycophenolic acid 💬		[2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
59Myeloablative Preparative Regimen----[3] 62, 65, 284 💬
60Phosphate[1] Phosphate ion---[32] 2, 3, 6, 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299 💬
61Prednisone[1] Prednisone[1] Prednisone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
62Reduced Intensity Preparative Regimen----[3] 62, 65, 284 💬
63Reduced Toxicity Ablative Regimen----[3] 62, 65, 284 💬
64Rimiducid[1] Rimiducid[1] Rimiducid 💬[1] CASP9 💬[35] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬[6] 19, 60, 65, 284, 285, 326 💬
65RITUXIMAB[1] Rituximab[1] Rituximab 💬[1] MS4A1 💬[1] Hematopoietic cell lineage 💬[48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
66SOTATERCEPT[1] Sotatercept[1] Sotatercept 💬[1] ACVR2A 💬[4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[2] 86, 284 💬
67Sotatercept with prednisone boost[2] Prednisone,
Sotatercept		[2] Prednisone ,
Sotatercept 💬		[2] ACVR2A,
NR3C1 💬		[5] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Neuroactive ligand-receptor interaction, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[1] 284 💬
68SSP-004184 100 mg----[1] 284 💬
69SSP-004184 100 mg Capsule----[1] 284 💬
70SSP-004184 250 mg----[1] 284 💬
71SSP-004184 250 mg Capsule----[1] 284 💬
72SSP-004184 375 mg----[1] 284 💬
73SSP-004184 375 mg Capsule----[1] 284 💬
74SSP-004184 50 mg----[1] 284 💬
75SSP-004184 50 mg Capsule----[1] 284 💬
76SSP-004184 500 mg----[1] 284 💬
77SSP-004184 500 mg Capsule----[1] 284 💬
78SSP-004184AQ 100 mg----[1] 284 💬
79SSP-004184AQ 100 mg Capsule----[1] 284 💬
80SSP-004184AQ 200 mg----[1] 284 💬
81SSP-004184AQ 200 mg Capsule----[1] 284 💬
82SSP-004184AQ 250 mg----[1] 284 💬
83SSP-004184AQ 250 mg Capsule----[1] 284 💬
84SSP-004184AQ 375 mg----[1] 284 💬
85SSP-004184AQ 375 mg Capsule----[1] 284 💬
86SSP-004184AQ 50 mg----[1] 284 💬
87SSP-004184AQ 50 mg Capsule----[1] 284 💬
88Tacrolimus[1] Tacrolimus[2] Tacrolimus ,
Tacrolimus 💬		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
89Thiotepa[1] Thiotepa[1] Thiotepa 💬--[12] 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285 💬
90Thiotepa--escalated dose[1] Thiotepa[1] Thiotepa 💬--[4] 19, 20, 65, 284 💬
91Thiotepa--single daily dose[1] Thiotepa[1] Thiotepa 💬--[4] 19, 20, 65, 284 💬
92Trifluoperazine[1] Trifluoperazine[2] Trifluoperazine maleate ,
Trifluoperazine 💬		[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 283, 284 💬