Bupropion ( DrugBank: Bupropion )


5 diseases
告示番号疾患名(ページ内リンク)臨床試験数
8ハンチントン病1
18脊髄小脳変性症(多系統萎縮症を除く。)1
21ミトコンドリア病1
96クローン病1
171ウィルソン病1

8. ハンチントン病


臨床試験数 : 229 薬物数 : 197 - (DrugBank : 60) / 標的遺伝子数 : 84 - 標的パスウェイ数 : 158
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
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gender
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size
PhaseCountries
1NCT01914965
(ClinicalTrials.gov)
June 201231/7/2013Apathy Cure Through Bupropion in Huntington's DiseaseA Randomized, Double-blind, Placebo-controlled Prospective Crossover Trial Investigating the Efficacy and Safety of the Treatment With Bupropion in Patients With Apathy in Huntington's DiseaseApathy;Huntington's DiseaseDrug: Bupropion;Drug: PlaceboCharite University, Berlin, GermanyUniversity of Ulm;Ruhr University of Bochum;University Hospital MuensterCompleted25 Years75 YearsBoth40Phase 2Germany

18. 脊髄小脳変性症(多系統萎縮症を除く。)


臨床試験数 : 71 薬物数 : 101 - (DrugBank : 30) / 標的遺伝子数 : 45 - 標的パスウェイ数 : 65
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT01716221
(ClinicalTrials.gov)
October 201225/10/2012An Objective Double-blind Evaluation of Bupropion and Citalopram in an Individual With Friedreich AtaxiaAn Objective Double-blind Evaluation of Bupropion and Citalopram in an Individual With Friedreich AtaxiaFriedreich AtaxiaDrug: bupropion & Citalopram;Drug: Bupropion & Placebo;Drug: Placebo & Citalopram;Drug: Placebo & PlaceboUniversity of Colorado, DenverNULLCompletedN/AN/AFemale1Phase 4NULL

21. ミトコンドリア病


臨床試験数 : 33 薬物数 : 43 - (DrugBank : 32) / 標的遺伝子数 : 47 - 標的パスウェイ数 : 67
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04643249
(ClinicalTrials.gov)
November 10, 202013/11/2020Drug-drug Interaction Study of KL1333 in Healthy SubjectsA Phase I, Open-label, Fixed-sequence, Crossover, Drug-drug Interaction Study to Investigate the Inhibition Potential of KL1333 on CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 in Healthy SubjectsMitochondrial DiseaseDrug: KL1333;Drug: Flurbiprofen;Drug: Dextromethorphan;Drug: Bupropion;Drug: Midazolam injection;Drug: Omeprazole;Drug: Caffeine;Drug: RepaglinideAbliva ABNULLCompleted18 Years65 YearsAll14Phase 1United Kingdom

96. クローン病


臨床試験数 : 2,400 薬物数 : 1,417 - (DrugBank : 267) / 標的遺伝子数 : 168 - 標的パスウェイ数 : 214
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00126373
(ClinicalTrials.gov)
May 20052/8/2005A Trial of Wellbutrin for Crohn's DiseaseA Randomized Controlled Trial of Wellbutrin for Crohn's DiseaseCrohn DiseaseDrug: Wellbutrin (bupropion)Altschuler, Eric, M.D.GlaxoSmithKlineCompleted18 YearsN/ABoth1Phase 2/Phase 3United States

171. ウィルソン病


臨床試験数 : 68 薬物数 : 79 - (DrugBank : 17) / 標的遺伝子数 : 3 - 標的パスウェイ数 : 28
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04526210
(ClinicalTrials.gov)
October 21, 202019/8/2020Study of ALXN1840 on the Metabolism of a CYP2B6 Substrate in Healthy ParticipantsA Phase 1, Randomized, 2-Period, 2-Sequence, Cross-over Study to Determine the Effect of ALXN1840 on the Metabolism of a CYP2B6 Substrate in Healthy ParticipantsWilson DiseaseDrug: ALXN1840;Drug: Bupropion HydrochlorideAlexion PharmaceuticalsNULLCompleted18 Years50 YearsAll54Phase 1United States