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 Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト) 

   e.g. "Sirolimus", "アダリムマブ", "MAP2K"    Synonyms (Drugs) were also searched for.

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8 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES  KEGG DRUG  DrugBank   指定難病告示番号
 1  cGMP-PKG signaling pathway 
 3 genes, 1 drug (DrugBank) and 11 diseases shown 
 3件: ADRA2A, ADRA2B, ADRA2C   D00514   Dexmedetomidine   11件: 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 
 D01205 
 2  GABAergic synapse 
 16 genes, 1 drug (DrugBank) and 8 diseases shown 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   8件: 6, 21, 22, 34, 46, 84, 98, 296 
 3  Morphine addiction 
 16 genes, 1 drug (DrugBank) and 8 diseases shown 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   8件: 6, 21, 22, 34, 46, 84, 98, 296 
 4  Neuroactive ligand-receptor interaction 
 19 genes, 2 drugs (DrugBank) and 16 diseases shown 
 3件: ADRA2A, ADRA2B, ADRA2C   D00514   Dexmedetomidine   11件: 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 
 D01205 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   8件: 6, 21, 22, 34, 46, 84, 98, 296 
 5  Nicotine addiction 
 16 genes, 1 drug (DrugBank) and 8 diseases shown 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   8件: 6, 21, 22, 34, 46, 84, 98, 296 
 6  Retrograde endocannabinoid signaling 
 16 genes, 1 drug (DrugBank) and 8 diseases shown 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   8件: 6, 21, 22, 34, 46, 84, 98, 296 
 7  Serotonergic synapse 
 3 genes, 1 drug (DrugBank) and 8 diseases shown 
 3件: GABRB1, GABRB2, GABRB3   D00549   Propofol   8件: 6, 21, 22, 34, 46, 84, 98, 296 
 8  Taste transduction 
 6 genes, 1 drug (DrugBank) and 8 diseases shown 
 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6   D00549   Propofol   8件: 6, 21, 22, 34, 46, 84, 98, 296 

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