Resveratrol ( DrugBank: Resveratrol )


6 diseases
告示番号疾患名(ページ内リンク)臨床試験数
2筋萎縮性側索硬化症2
8ハンチントン病1
18脊髄小脳変性症(多系統萎縮症を除く。)2
89リンパ脈管筋腫症1
113筋ジストロフィー1
299嚢胞性線維症1

2. 筋萎縮性側索硬化症


臨床試験数 : 624 薬物数 : 623 - (DrugBank : 160) / 標的遺伝子数 : 172 - 標的パスウェイ数 : 225
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04654689
(ClinicalTrials.gov)
November 20, 202113/11/2020Impact of the Combined Treatment of Liposomed Polyphenols With G04CB02 on the ALS PatientsImpact of the Combined Treatment of Curcumin and Resveratrol Liposomed Polyphenols With G04CB02 on the Clinical Improvement of ALS PatientsAmyotrophic Lateral SclerosisDietary Supplement: Liposomed polyphenols resveratrol and curcumin;Other: Placebo for liposomed resveratrol and curcumin;Dietary Supplement: Isocaloric Diet;Drug: G04CB02;Other: Placebo microcrystalline methylcelluloseFundación Universidad Católica de Valencia San Vicente MártirNULLRecruiting18 Years75 YearsAll60Phase 2Spain
2EUCTR2021-001989-38-ES
(EUCTR)
08/07/202114/06/2021COMPARISON OF THE COMBINED TREATMENT OF THE LIPOSOMATED POLYPHENOLS CÚRCULA AND RESVERATROL® WITH DUTASTERIDE, IN THE IMPROVEMENT OF PATIENTS WITH ELA WHO ARE BEING TREATED WITH RILUZOLEIMPACT OF THE COMBINED TREATMENT OF THE LIPOSOMATED POLYPHENOLS CÚRCULA AND RESVERATROL® WITH DUTASTERIDE, IN THE CLINICAL IMPROVEMENT OF PATIENTS WITH ALS TREATED WITH RILUZOLE - IMCRELA Amyotrophic Lateral Sclerosis
MedDRA version: 21.1;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]
Trade Name: Dutasterida
Product Name: Dutasterida
INN or Proposed INN: DUTASTERIDE
Other descriptive name: DUTASTERIDE
Facultad de medicina y ciencias de la salud de la Universidad Católica de ValenciaNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
100Phase 2Spain

8. ハンチントン病


臨床試験数 : 229 薬物数 : 197 - (DrugBank : 60) / 標的遺伝子数 : 84 - 標的パスウェイ数 : 158
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT02336633
(ClinicalTrials.gov)
July 20158/1/2015Resveratrol and Huntington DiseaseMetabolic Intervention Using Resveratrol in Patients With Huntington DiseaseHuntington DiseaseDietary Supplement: Resveratrol;Other: PlaceboAssistance Publique - Hôpitaux de ParisNULLCompleted18 YearsN/AAll102N/AFrance

18. 脊髄小脳変性症(多系統萎縮症を除く。)


臨床試験数 : 71 薬物数 : 101 - (DrugBank : 30) / 標的遺伝子数 : 45 - 標的パスウェイ数 : 65
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03933163
(ClinicalTrials.gov)
May 23, 201916/4/2019Micronised Resveratrol as a Treatment for Friedreich AtaxiaA Randomised Placebo-controlled Crossover Trial of Micronised Resveratrol as a Treatment for Friedreich AtaxiaFriedreich AtaxiaDrug: ResveratrolMurdoch Childrens Research InstituteNULLActive, not recruiting16 YearsN/AAll40Phase 2Australia
2NCT01339884
(ClinicalTrials.gov)
April 201114/4/2011A Study of Resveratrol as Treatment for Friedreich AtaxiaAn Open Label Clinical Pilot Study of Resveratrol as Treatment for Friedreich AtaxiaFriedreich AtaxiaDrug: ResveratrolMurdoch Childrens Research InstituteFriedreich's Ataxia Research AllianceCompleted18 YearsN/ABoth27Phase 1/Phase 2Australia

89. リンパ脈管筋腫症


臨床試験数 : 39 薬物数 : 46 - (DrugBank : 20) / 標的遺伝子数 : 27 - 標的パスウェイ数 : 137
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03253913
(ClinicalTrials.gov)
March 31, 201810/8/2017Resveratrol and Sirolimus in Lymphangioleiomyomatosis TrialResveratrol and Sirolimus in Lymphangioleiomyomatosis Trial (RESULT)LymphangioleiomyomatosisDrug: Sirolimus;Drug: ResveratrolUniversity of CincinnatiNational Heart, Lung, and Blood Institute (NHLBI)Unknown status18 YearsN/AFemale25Phase 2United States

113. 筋ジストロフィー


臨床試験数 : 622 薬物数 : 494 - (DrugBank : 99) / 標的遺伝子数 : 59 - 標的パスウェイ数 : 168
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1JPRN-UMIN000014836
2014/05/0112/08/2014A pilot study to evaluate efficacy and safety of resveratrol for muscular dystrophy. Duchenne muscular dystrophy, Becker muscular dystrophy, Fukuyama congenital muscular dystrophy500mg resveratrol is administrated daily for 8 weeks.
Subsequently, resveratrol is increased to 1500mg by 500mg every 8 weeks.
Sapporo Medical UniversityNULLComplete: follow-up complete12years-oldNot applicableMale and Female10Not selectedJapan

299. 嚢胞性線維症


臨床試験数 : 1,696 薬物数 : 1,658 - (DrugBank : 272) / 標的遺伝子数 : 96 - 標的パスウェイ数 : 170
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04166396
(ClinicalTrials.gov)
February 17, 202014/11/2019Non-pulmonary Contributors of Exercise Intolerance in Patients With Cystic FibrosisNon-pulmonary Contributors of Exercise Intolerance in Patients With Cystic FibrosisCystic FibrosisDietary Supplement: Resveratrol;Dietary Supplement: NR;Dietary Supplement: PlaceboVirginia Commonwealth UniversityNULLRecruiting18 YearsN/AAll36N/AUnited States