Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CFTR [3] Tight junction, Pancreatic secretion, Vibrio cholerae infection D09916 Ivacaftor [1] 299
2 CFTR [3] Tight junction, Pancreatic secretion, Vibrio cholerae infection D10134 Lumacaftor [1] 299
3 CFTR [3] Tight junction, Pancreatic secretion, Vibrio cholerae infection D11041 Tezacaftor [1] 299
4 CFTR [3] Tight junction, Pancreatic secretion, Vibrio cholerae infection D11423 Deutivacaftor [1] 299
5 CFTR [3] Tight junction, Pancreatic secretion, Vibrio cholerae infection D11507 Elexacaftor [1] 299
6 CFTR [3] Tight junction, Pancreatic secretion, Vibrio cholerae infection D11724 Galicaftor [1] 299
7 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00113 Atropine [2] 2, 299
8 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00138 Scopolamine [1] 2
9 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00270 Chlorpromazine [1] 254
10 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00397 Tropicamide [1] 6
11 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00465 Oxybutynin [3] 6, 13, 53
12 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00525 Pilocarpine [3] 6, 53, 299
13 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00646 Tolterodine [2] 17, 53
14 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D03654 Darifenacin [2] 6, 13
15 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D07226 Fesoterodine [1] 6
16 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D07667 Cevimeline [1] 53
17 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D08441 Propiverine [1] 226
18 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D08522 Solifenacin [3] 6, 13, 53
19 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D08638 Trihexyphenidyl [2] 5, 6
20 CHRM3 [5] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D11383 Blarcamesine [1] 156
21 AMY2A [3] Starch and sucrose metabolism, Salivary secretion, Pancreatic secretion D00216 Acarbose [1] 298
22 AMY2B [3] Starch and sucrose metabolism, Salivary secretion, Pancreatic secretion D00216 Acarbose [1] 298
23 KCNQ1 [3] Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection D02910 Amiodarone [2] 28, 127
24 KCNQ1 [3] Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection D09569 Ezogabine [2] 2, 144
25 ATP1A1 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00297 Digitoxin [1] 299
26 ATP1A1 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00298 Digoxin [3] 8, 46, 210
27 ATP1A2 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00297 Digitoxin [1] 299
28 ATP1A2 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00298 Digoxin [3] 8, 46, 210
29 ATP1A3 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00297 Digitoxin [1] 299
30 ATP1A3 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00298 Digoxin [3] 8, 46, 210
31 ATP1A4 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00297 Digitoxin [1] 299
32 ATP1A4 [6] Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Pancreatic secretion, Protein digestion and absorption D00298 Digoxin [3] 8, 46, 210
33 PRKCB [18] Ras signaling pathway, Rap1 signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Parathyroid hormone synthesis, secretion and action, Salivary secretion, Pancreatic secretion, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Pathways in cancer, Proteoglycans in cancer D11935 Enzastaurin [1] 168
34 SLC12A2 [3] Salivary secretion, Pancreatic secretion, Vibrio cholerae infection D00247 Bumetanide [2] 6, 158
35 SLC12A2 [3] Salivary secretion, Pancreatic secretion, Vibrio cholerae infection D00331 Furosemide [2] 6, 86
36 CA2 [2] Proximal tubule bicarbonate reclamation, Pancreatic secretion D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
37 CA2 [2] Proximal tubule bicarbonate reclamation, Pancreatic secretion D00518 Diclofenamide [1] 114
38 CA2 [2] Proximal tubule bicarbonate reclamation, Pancreatic secretion D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
39 CA2 [2] Proximal tubule bicarbonate reclamation, Pancreatic secretion D07871 Dorzolamide [1] 90
40 CD38 [2] Salivary secretion, Pancreatic secretion D10777 Daratumumab [5] 13, 28, 48, 49, 63
41 CD38 [2] Salivary secretion, Pancreatic secretion D11050 Isatuximab [3] 28, 61, 283
42 CD38 [2] Salivary secretion, Pancreatic secretion D11945 Mezagitamab [2] 63, 66