Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CHRM3 [1] Taste transduction D00113 Atropine [2] 2, 299
2 CHRM3 [1] Taste transduction D00138 Scopolamine [1] 2
3 CHRM3 [1] Taste transduction D00270 Chlorpromazine [1] 254
4 CHRM3 [1] Taste transduction D00397 Tropicamide [1] 6
5 CHRM3 [1] Taste transduction D00465 Oxybutynin [3] 6, 13, 53
6 CHRM3 [1] Taste transduction D00525 Pilocarpine [3] 6, 53, 299
7 CHRM3 [1] Taste transduction D00646 Tolterodine [2] 17, 53
8 CHRM3 [1] Taste transduction D03654 Darifenacin [2] 6, 13
9 CHRM3 [1] Taste transduction D07226 Fesoterodine [1] 6
10 CHRM3 [1] Taste transduction D07667 Cevimeline [1] 53
11 CHRM3 [1] Taste transduction D08441 Propiverine [1] 226
12 CHRM3 [1] Taste transduction D08522 Solifenacin [3] 6, 13, 53
13 CHRM3 [1] Taste transduction D08638 Trihexyphenidyl [2] 5, 6
14 CHRM3 [1] Taste transduction D11383 Blarcamesine [1] 156
15 HTR3C [1] Taste transduction D00283 Clozapine [1] 6
16 HTR3C [1] Taste transduction D00456 Ondansetron [3] 6, 97, 107
17 HTR3C [1] Taste transduction D07867 Dolasetron [1] 46
18 HTR3C [1] Taste transduction D10184 Vortioxetine [1] 6
19 HTR3D [1] Taste transduction D00283 Clozapine [1] 6
20 HTR3D [1] Taste transduction D00456 Ondansetron [3] 6, 97, 107
21 HTR3D [1] Taste transduction D07867 Dolasetron [1] 46
22 HTR3D [1] Taste transduction D10184 Vortioxetine [1] 6
23 GABBR1 [1] Taste transduction D00241 Baclofen [8] 2, 10, 13, 18, 65, 70, 149, 206
24 GABBR1 [1] Taste transduction D08861 Arbaclofen Placarbil [1] 13
25 GABBR1 [1] Taste transduction D09791 Arbaclofen [2] 13, 206
26 GABBR1 [1] Taste transduction D12240 Valiloxybate [1] 6
27 GABRA1 [1] Taste transduction D00225 Alprazolam [2] 8, 75
28 GABRA1 [1] Taste transduction D00280 Clonazepam [1] 6
29 GABRA1 [1] Taste transduction D00293 Diazepam [3] 46, 155, 298
30 GABRA1 [1] Taste transduction D00365 Lorazepam [1] 36
31 GABRA1 [1] Taste transduction D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
32 GABRA1 [1] Taste transduction D00548 Etomidate [1] 6
33 GABRA1 [1] Taste transduction D00549 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296
34 GABRA1 [1] Taste transduction D00550 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
35 GABRA1 [1] Taste transduction D00697 Flumazenil [5] 6, 13, 17, 18, 206
36 GABRA1 [1] Taste transduction D01253 Clobazam [2] 140, 144
37 GABRA1 [1] Taste transduction D01372 Zopiclone [1] 6
38 GABRA1 [1] Taste transduction D02624 Eszopiclone [3] 6, 13, 46
39 GABRA1 [1] Taste transduction D04282 Gaboxadol [2] 201, 206
40 GABRA1 [1] Taste transduction D04300 Ganaxolone [4] 145, 152, 158, 206
41 GABRA1 [1] Taste transduction D07784 Delorazepam [3] 6, 46, 97
42 GABRA1 [1] Taste transduction D08690 Zolpidem [3] 5, 6, 46
43 GABRA1 [1] Taste transduction D11149 Brexanolone [1] 205
44 GABRA2 [1] Taste transduction D00225 Alprazolam [2] 8, 75
45 GABRA2 [1] Taste transduction D00280 Clonazepam [1] 6
46 GABRA2 [1] Taste transduction D00293 Diazepam [3] 46, 155, 298
47 GABRA2 [1] Taste transduction D00365 Lorazepam [1] 36
48 GABRA2 [1] Taste transduction D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
49 GABRA2 [1] Taste transduction D00549 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296
50 GABRA2 [1] Taste transduction D00550 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
51 GABRA2 [1] Taste transduction D00697 Flumazenil [5] 6, 13, 17, 18, 206
52 GABRA2 [1] Taste transduction D01253 Clobazam [2] 140, 144
53 GABRA2 [1] Taste transduction D01372 Zopiclone [1] 6
54 GABRA2 [1] Taste transduction D02624 Eszopiclone [3] 6, 13, 46
55 GABRA2 [1] Taste transduction D04282 Gaboxadol [2] 201, 206
56 GABRA2 [1] Taste transduction D04300 Ganaxolone [4] 145, 152, 158, 206
57 GABRA2 [1] Taste transduction D07784 Delorazepam [3] 6, 46, 97
58 GABRA2 [1] Taste transduction D08690 Zolpidem [3] 5, 6, 46
59 GABRA2 [1] Taste transduction D11149 Brexanolone [1] 205
60 GABRA3 [1] Taste transduction D00225 Alprazolam [2] 8, 75
61 GABRA3 [1] Taste transduction D00280 Clonazepam [1] 6
62 GABRA3 [1] Taste transduction D00293 Diazepam [3] 46, 155, 298
63 GABRA3 [1] Taste transduction D00365 Lorazepam [1] 36
64 GABRA3 [1] Taste transduction D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
65 GABRA3 [1] Taste transduction D00549 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296
66 GABRA3 [1] Taste transduction D00550 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
67 GABRA3 [1] Taste transduction D00697 Flumazenil [5] 6, 13, 17, 18, 206
68 GABRA3 [1] Taste transduction D01253 Clobazam [2] 140, 144
69 GABRA3 [1] Taste transduction D01372 Zopiclone [1] 6
70 GABRA3 [1] Taste transduction D02624 Eszopiclone [3] 6, 13, 46
71 GABRA3 [1] Taste transduction D04282 Gaboxadol [2] 201, 206
72 GABRA3 [1] Taste transduction D04300 Ganaxolone [4] 145, 152, 158, 206
73 GABRA3 [1] Taste transduction D07784 Delorazepam [3] 6, 46, 97
74 GABRA3 [1] Taste transduction D08690 Zolpidem [3] 5, 6, 46
75 GABRA3 [1] Taste transduction D11149 Brexanolone [1] 205
76 GABRA4 [1] Taste transduction D00225 Alprazolam [2] 8, 75
77 GABRA4 [1] Taste transduction D00280 Clonazepam [1] 6
78 GABRA4 [1] Taste transduction D00293 Diazepam [3] 46, 155, 298
79 GABRA4 [1] Taste transduction D00365 Lorazepam [1] 36
80 GABRA4 [1] Taste transduction D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
81 GABRA4 [1] Taste transduction D00549 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296
82 GABRA4 [1] Taste transduction D00550 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
83 GABRA4 [1] Taste transduction D00697 Flumazenil [5] 6, 13, 17, 18, 206
84 GABRA4 [1] Taste transduction D01253 Clobazam [2] 140, 144
85 GABRA4 [1] Taste transduction D01372 Zopiclone [1] 6
86 GABRA4 [1] Taste transduction D02624 Eszopiclone [3] 6, 13, 46
87 GABRA4 [1] Taste transduction D04282 Gaboxadol [2] 201, 206
88 GABRA4 [1] Taste transduction D04300 Ganaxolone [4] 145, 152, 158, 206
89 GABRA4 [1] Taste transduction D07784 Delorazepam [3] 6, 46, 97
90 GABRA4 [1] Taste transduction D08690 Zolpidem [3] 5, 6, 46
91 GABRA4 [1] Taste transduction D11149 Brexanolone [1] 205
92 GABRA5 [1] Taste transduction D00225 Alprazolam [2] 8, 75
93 GABRA5 [1] Taste transduction D00280 Clonazepam [1] 6
94 GABRA5 [1] Taste transduction D00293 Diazepam [3] 46, 155, 298
95 GABRA5 [1] Taste transduction D00365 Lorazepam [1] 36
96 GABRA5 [1] Taste transduction D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
97 GABRA5 [1] Taste transduction D00549 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296
98 GABRA5 [1] Taste transduction D00550 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
99 GABRA5 [1] Taste transduction D00697 Flumazenil [5] 6, 13, 17, 18, 206
100 GABRA5 [1] Taste transduction D01253 Clobazam [2] 140, 144
101 GABRA5 [1] Taste transduction D01372 Zopiclone [1] 6
102 GABRA5 [1] Taste transduction D02624 Eszopiclone [3] 6, 13, 46
103 GABRA5 [1] Taste transduction D04282 Gaboxadol [2] 201, 206
104 GABRA5 [1] Taste transduction D04300 Ganaxolone [4] 145, 152, 158, 206
105 GABRA5 [1] Taste transduction D07784 Delorazepam [3] 6, 46, 97
106 GABRA5 [1] Taste transduction D08690 Zolpidem [3] 5, 6, 46
107 GABRA5 [1] Taste transduction D11149 Brexanolone [1] 205
108 GABRA6 [1] Taste transduction D00225 Alprazolam [2] 8, 75
109 GABRA6 [1] Taste transduction D00280 Clonazepam [1] 6
110 GABRA6 [1] Taste transduction D00293 Diazepam [3] 46, 155, 298
111 GABRA6 [1] Taste transduction D00365 Lorazepam [1] 36
112 GABRA6 [1] Taste transduction D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
113 GABRA6 [1] Taste transduction D00549 Propofol [9] 6, 21, 22, 34, 46, 70, 75, 98, 296
114 GABRA6 [1] Taste transduction D00550 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
115 GABRA6 [1] Taste transduction D00697 Flumazenil [5] 6, 13, 17, 18, 206
116 GABRA6 [1] Taste transduction D01253 Clobazam [2] 140, 144
117 GABRA6 [1] Taste transduction D01372 Zopiclone [1] 6
118 GABRA6 [1] Taste transduction D02624 Eszopiclone [3] 6, 13, 46
119 GABRA6 [1] Taste transduction D04282 Gaboxadol [2] 201, 206
120 GABRA6 [1] Taste transduction D04300 Ganaxolone [4] 145, 152, 158, 206
121 GABRA6 [1] Taste transduction D07784 Delorazepam [3] 6, 46, 97
122 GABRA6 [1] Taste transduction D08690 Zolpidem [3] 5, 6, 46
123 GABRA6 [1] Taste transduction D11149 Brexanolone [1] 205
124 HTR3E [1] Taste transduction D00283 Clozapine [1] 6
125 HTR3E [1] Taste transduction D00456 Ondansetron [3] 6, 97, 107
126 HTR3E [1] Taste transduction D07867 Dolasetron [1] 46
127 HTR3E [1] Taste transduction D10184 Vortioxetine [1] 6
128 HTR1A [1] Taste transduction D01164 Aripiprazole [2] 6, 206
129 HTR1A [1] Taste transduction D07593 Buspirone [2] 6, 51
130 HTR1A [1] Taste transduction D09397 Pardoprunox [1] 6
131 HTR1A [1] Taste transduction D09997 Cariprazine [1] 21
132 HTR1A [1] Taste transduction D10184 Vortioxetine [1] 6
133 HTR1B [1] Taste transduction D00415 Zolmitriptan [1] 6
134 HTR1D [1] Taste transduction D00415 Zolmitriptan [1] 6
135 HTR1D [1] Taste transduction D07945 Fenfluramine [4] 140, 144, 145, 149
136 HTR3A [1] Taste transduction D00274 Cisapride [1] 13
137 HTR3A [1] Taste transduction D00283 Clozapine [1] 6
138 HTR3A [1] Taste transduction D00456 Ondansetron [3] 6, 97, 107
139 HTR3A [1] Taste transduction D02092 Cisapride [1] 13
140 HTR3A [1] Taste transduction D07867 Dolasetron [1] 46
141 HTR3A [1] Taste transduction D10184 Vortioxetine [1] 6
142 P2RX3 [1] Taste transduction D11349 Gefapixant [2] 85, 226
143 PDE1A [1] Taste transduction D00227 Aminophylline [1] 63
144 PDE1A [1] Taste transduction D00371 Theophylline [2] 236, 299
145 PDE1A [1] Taste transduction D06103 Theophylline [2] 236, 299
146 PDE1A [1] Taste transduction D07546 Bucladesine [1] 246
147 PDE1A [1] Taste transduction D07961 Flavoxate [1] 226
148 PDE1C [1] Taste transduction D00227 Aminophylline [1] 63
149 PDE1C [1] Taste transduction D00371 Theophylline [2] 236, 299
150 PDE1C [1] Taste transduction D06103 Theophylline [2] 236, 299
151 PDE1C [1] Taste transduction D07546 Bucladesine [1] 246
152 PDE1C [1] Taste transduction D07961 Flavoxate [1] 226
153 PDE1B [1] Taste transduction D00227 Aminophylline [1] 63
154 PDE1B [1] Taste transduction D00371 Theophylline [2] 236, 299
155 PDE1B [1] Taste transduction D00528 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265
156 PDE1B [1] Taste transduction D01453 Caffeine [8] 2, 6, 21, 46, 78, 96, 97, 265
157 PDE1B [1] Taste transduction D06103 Theophylline [2] 236, 299
158 PDE1B [1] Taste transduction D07546 Bucladesine [1] 246
159 PDE1B [1] Taste transduction D07961 Flavoxate [1] 226
160 SCN2A [1] Taste transduction D00252 Carbamazepine [3] 6, 13, 231
161 SCN2A [1] Taste transduction D00354 Lamotrigine [5] 13, 34, 38, 114, 144
162 SCN2A [1] Taste transduction D00358 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
163 SCN2A [1] Taste transduction D00512 Phenytoin [1] 13
164 SCN2A [1] Taste transduction D00533 Oxcarbazepine [1] 13
165 SCN2A [1] Taste transduction D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
166 SCN2A [1] Taste transduction D00538 Zonisamide [1] 6
167 SCN2A [1] Taste transduction D02910 Amiodarone [2] 28, 127
168 SCN2A [1] Taste transduction D03492 Cibenzoline [1] 58
169 SCN2A [1] Taste transduction D05775 Rufinamide [1] 144
170 SCN2A [1] Taste transduction D07552 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298
171 SCN2A [1] Taste transduction D07962 Flecainide [1] 6
172 SCN2A [1] Taste transduction D08116 Levobupivacaine [1] 46
173 SCN2A [1] Taste transduction D08127 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
174 SCN2A [1] Taste transduction D08215 Mexiletine [5] 1, 2, 10, 113, 114
175 SCN2A [1] Taste transduction D08319 Oxybuprocaine [1] 6
176 SCN2A [1] Taste transduction D08458 Quinidine [3] 2, 8, 13
177 SCN2A [1] Taste transduction D08490 Ropivacaine [4] 22, 36, 46, 70
178 SCN2A [1] Taste transduction D11155 Eleclazine [1] 58
179 SCN3A [1] Taste transduction D00252 Carbamazepine [3] 6, 13, 231
180 SCN3A [1] Taste transduction D00354 Lamotrigine [5] 13, 34, 38, 114, 144
181 SCN3A [1] Taste transduction D00358 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
182 SCN3A [1] Taste transduction D00512 Phenytoin [1] 13
183 SCN3A [1] Taste transduction D00533 Oxcarbazepine [1] 13
184 SCN3A [1] Taste transduction D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
185 SCN3A [1] Taste transduction D00538 Zonisamide [1] 6
186 SCN3A [1] Taste transduction D02910 Amiodarone [2] 28, 127
187 SCN3A [1] Taste transduction D03492 Cibenzoline [1] 58
188 SCN3A [1] Taste transduction D05775 Rufinamide [1] 144
189 SCN3A [1] Taste transduction D07299 Lacosamide [4] 2, 46, 149, 298
190 SCN3A [1] Taste transduction D07552 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298
191 SCN3A [1] Taste transduction D07962 Flecainide [1] 6
192 SCN3A [1] Taste transduction D08116 Levobupivacaine [1] 46
193 SCN3A [1] Taste transduction D08127 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
194 SCN3A [1] Taste transduction D08215 Mexiletine [5] 1, 2, 10, 113, 114
195 SCN3A [1] Taste transduction D08319 Oxybuprocaine [1] 6
196 SCN3A [1] Taste transduction D08458 Quinidine [3] 2, 8, 13
197 SCN3A [1] Taste transduction D08490 Ropivacaine [4] 22, 36, 46, 70
198 SCN3A [1] Taste transduction D11155 Eleclazine [1] 58
199 SCN9A [1] Taste transduction D00252 Carbamazepine [3] 6, 13, 231
200 SCN9A [1] Taste transduction D00354 Lamotrigine [5] 13, 34, 38, 114, 144
201 SCN9A [1] Taste transduction D00358 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
202 SCN9A [1] Taste transduction D00512 Phenytoin [1] 13
203 SCN9A [1] Taste transduction D00533 Oxcarbazepine [1] 13
204 SCN9A [1] Taste transduction D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
205 SCN9A [1] Taste transduction D00538 Zonisamide [1] 6
206 SCN9A [1] Taste transduction D02910 Amiodarone [2] 28, 127
207 SCN9A [1] Taste transduction D03492 Cibenzoline [1] 58
208 SCN9A [1] Taste transduction D05775 Rufinamide [1] 144
209 SCN9A [1] Taste transduction D07299 Lacosamide [4] 2, 46, 149, 298
210 SCN9A [1] Taste transduction D07552 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298
211 SCN9A [1] Taste transduction D07962 Flecainide [1] 6
212 SCN9A [1] Taste transduction D08116 Levobupivacaine [1] 46
213 SCN9A [1] Taste transduction D08127 Lidocaine [13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
214 SCN9A [1] Taste transduction D08215 Mexiletine [5] 1, 2, 10, 113, 114
215 SCN9A [1] Taste transduction D08319 Oxybuprocaine [1] 6
216 SCN9A [1] Taste transduction D08458 Quinidine [3] 2, 8, 13
217 SCN9A [1] Taste transduction D08490 Ropivacaine [4] 22, 36, 46, 70
218 SCN9A [1] Taste transduction D11155 Eleclazine [1] 58
219 SCNN1A [1] Taste transduction D07447 Amiloride [4] 13, 67, 225, 299
220 SCNN1B [1] Taste transduction D07447 Amiloride [4] 13, 67, 225, 299
221 SCNN1G [1] Taste transduction D07447 Amiloride [4] 13, 67, 225, 299
222 CACNA1C [3] Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D00349 Isradipine [1] 6
223 CACNA1C [3] Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D00437 Nifedipine [2] 50, 81
224 CACNA1C [3] Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
225 CACNA1C [3] Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D01173 Cilnidipine [1] 67
226 CACNA1C [3] Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D01908 Nilvadipine [1] 90
227 CACNA1C [3] Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D02356 Verapamil [4] 58, 96, 140, 167
228 CACNA1C [3] Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D07450 Amlodipine [4] 13, 51, 67, 298
229 CACNA1C [3] Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D07845 Diltiazem [3] 51, 58, 86
230 CACNA1C [3] Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D08270 Nicardipine [2] 70, 86
231 CACNA1C [3] Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D08340 Perhexiline [2] 58, 272
232 CACNA1C [3] Vascular smooth muscle contraction, Taste transduction, Type II diabetes mellitus D08441 Propiverine [1] 226
233 TAS1R2 [1] Taste transduction D02381 Aspartame [4] 6, 13, 67, 86
234 TAS1R3 [1] Taste transduction D02381 Aspartame [4] 6, 13, 67, 86
235 HTR3B [1] Taste transduction D00283 Clozapine [1] 6
236 HTR3B [1] Taste transduction D00456 Ondansetron [3] 6, 97, 107
237 HTR3B [1] Taste transduction D07867 Dolasetron [1] 46
238 HTR3B [1] Taste transduction D10184 Vortioxetine [1] 6
239 GABBR2 [1] Taste transduction D00241 Baclofen [8] 2, 10, 13, 18, 65, 70, 149, 206
240 GABBR2 [1] Taste transduction D08861 Arbaclofen Placarbil [1] 13
241 GABBR2 [1] Taste transduction D09791 Arbaclofen [2] 13, 206
242 GABBR2 [1] Taste transduction D12240 Valiloxybate [1] 6