Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 MAPK14 [6] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
2 MAPK14 [6] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
3 CSF2 [2] TNF signaling pathway, Transcriptional misregulation in cancer D11343 Otilimab [1] 46
4 IL1B [5] Toll-like receptor signaling pathway, TNF signaling pathway, Type I diabetes mellitus, Yersinia infection, Tuberculosis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
5 IL1B [5] Toll-like receptor signaling pathway, TNF signaling pathway, Type I diabetes mellitus, Yersinia infection, Tuberculosis D06635 Rilonacept [4] 51, 106, 107, 266
6 IL1B [5] Toll-like receptor signaling pathway, TNF signaling pathway, Type I diabetes mellitus, Yersinia infection, Tuberculosis D09315 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
7 IL1B [5] Toll-like receptor signaling pathway, TNF signaling pathway, Type I diabetes mellitus, Yersinia infection, Tuberculosis D09911 Gevokizumab [4] 41, 50, 56, 269
8 IL6 [6] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
9 IL6 [6] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer D08976 Pomalidomide [5] 28, 51, 85, 227, 331
10 IL6 [6] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer D09669 Siltuximab [2] 28, 331
11 IL6 [6] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer D10080 Sirukumab [2] 41, 46
12 IL6 [6] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Tuberculosis, Transcriptional misregulation in cancer D12487 Olokizumab [2] 46, 96
13 LTA [3] Viral protein interaction with cytokine and cytokine receptor, TNF signaling pathway, Type I diabetes mellitus D00742 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
14 LTA [3] Viral protein interaction with cytokine and cytokine receptor, TNF signaling pathway, Type I diabetes mellitus D10187 Pateclizumab [1] 46
15 MAP3K5 [1] TNF signaling pathway D10988 Selonsertib [1] 86
16 NFKB1 [7] Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis D01146 Iguratimod [5] 46, 51, 53, 271, 300
17 PIK3CA [6] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11011 Alpelisib [1] 138
18 PIK3CA [6] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
19 PIK3CB [6] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
20 PIK3CD [6] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
21 PIK3CD [6] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11437 Parsaclisib [3] 35, 53, 61
22 MAPK11 [6] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
23 MAPK11 [6] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
24 MAPK13 [6] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
25 MAPK13 [6] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
26 MAP2K1 [5] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection D09666 Selumetinib [1] 34
27 MAP2K1 [5] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection D10175 Trametinib [4] 2, 34, 279, 280
28 MAP2K1 [5] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection D10405 Cobimetinib [1] 280
29 MAP2K1 [5] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection D10604 Binimetinib [1] 34
30 MAP2K1 [5] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection D11675 Mirdametinib [1] 34
31 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D00109 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
32 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D00118 Naproxen [4] 13, 46, 107, 271
33 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D00120 Sulindac [1] 206
34 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D00126 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299
35 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D00130 Diflunisal [1] 28
36 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D00132 Ketoprofen [1] 46
37 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D00141 Indomethacin [3] 225, 271, 298
38 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D00217 Acetaminophen [15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
39 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D00315 Etodolac [1] 46
40 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D00330 Flurbiprofen [3] 13, 21, 46
41 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D00428 Salsalate [1] 5
42 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D00567 Celecoxib [10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
43 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D00568 Rofecoxib [1] 46
44 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D00969 Meloxicam [4] 46, 49, 271, 296
45 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D01049 Nimesulide [1] 46
46 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D01183 Tolfenamic acid [1] 5
47 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D01545 Aceclofenac [1] 46
48 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D02709 Valdecoxib [1] 46
49 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D03710 Etoricoxib [2] 46, 271
50 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D03714 Lumiracoxib [1] 46
51 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D03716 Parecoxib [2] 46, 271
52 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D07816 Diclofenac [5] 13, 34, 46, 78, 271
53 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D08104 Ketorolac [2] 70, 226
54 PTGS2 [2] VEGF signaling pathway, TNF signaling pathway D08149 Loxoprofen [2] 46, 271
55 RELA [7] Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis D12181 Edasalonexent [1] 113
56 MAPK12 [6] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
57 MAPK12 [6] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
58 CCL2 [3] Viral protein interaction with cytokine and cytokine receptor, TNF signaling pathway, Yersinia infection D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
59 TNF [8] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D00742 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
60 TNF [8] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D00754 Thalidomide [20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
61 TNF [8] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
62 TNF [8] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D02597 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271
63 TNF [8] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D02598 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
64 TNF [8] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D03441 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271
65 TNF [8] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D04358 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271
66 TNF [8] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D04687 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331
67 TNF [8] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D05393 Pegsunercept [1] 46
68 TNF [8] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D08976 Pomalidomide [5] 28, 51, 85, 227, 331
69 TNF [8] Viral protein interaction with cytokine and cytokine receptor, Toll-like receptor signaling pathway, TNF signaling pathway, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D09944 Ozoralizumab [1] 46