Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CDK4 [4] Tight junction, T cell receptor signaling pathway, Viral carcinogenesis, Small cell lung cancer D10688 Abemaciclib [1] 34
2 CDK6 [2] Viral carcinogenesis, Small cell lung cancer D10688 Abemaciclib [1] 34
3 NFKB1 [12] Sphingolipid signaling pathway, Toll-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Small cell lung cancer D01146 Iguratimod [5] 46, 51, 53, 271, 300
4 PIK3CA [11] Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis, Small cell lung cancer D11011 Alpelisib [1] 138
5 PIK3CA [11] Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis, Small cell lung cancer D11158 Leniolisib [2] 53, 65
6 PIK3CB [11] Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis, Small cell lung cancer D11158 Leniolisib [2] 53, 65
7 PIK3CD [11] Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis, Small cell lung cancer D11158 Leniolisib [2] 53, 65
8 PIK3CD [11] Sphingolipid signaling pathway, VEGF signaling pathway, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis, Small cell lung cancer D11437 Parsaclisib [3] 35, 53, 61
9 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00109 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
10 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00118 Naproxen [4] 13, 46, 107, 271
11 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00120 Sulindac [1] 206
12 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00126 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299
13 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00130 Diflunisal [1] 28
14 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00132 Ketoprofen [1] 46
15 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00141 Indomethacin [3] 225, 271, 298
16 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00217 Acetaminophen [15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
17 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00315 Etodolac [1] 46
18 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00330 Flurbiprofen [3] 13, 21, 46
19 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00428 Salsalate [1] 5
20 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00567 Celecoxib [10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
21 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00568 Rofecoxib [1] 46
22 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D00969 Meloxicam [4] 46, 49, 271, 296
23 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D01049 Nimesulide [1] 46
24 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D01183 Tolfenamic acid [1] 5
25 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D01545 Aceclofenac [1] 46
26 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D02709 Valdecoxib [1] 46
27 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D03710 Etoricoxib [2] 46, 271
28 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D03714 Lumiracoxib [1] 46
29 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D03716 Parecoxib [2] 46, 271
30 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D07816 Diclofenac [5] 13, 34, 46, 78, 271
31 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D08104 Ketorolac [2] 70, 226
32 PTGS2 [3] VEGF signaling pathway, TNF signaling pathway, Small cell lung cancer D08149 Loxoprofen [2] 46, 271
33 RARB [1] Small cell lung cancer D00094 Tretinoin [6] 2, 62, 63, 75, 94, 231
34 RARB [1] Small cell lung cancer D00348 Isotretinoin [4] 36, 39, 159, 160
35 RARB [1] Small cell lung cancer D02754 Acitretin [1] 37
36 RARB [1] Small cell lung cancer D02815 Alitretinoin [1] 49
37 RARB [1] Small cell lung cancer D04162 Fenretinide [1] 299
38 RARB [1] Small cell lung cancer D06543 Vitamin A [3] 13, 53, 90
39 BCL2 [4] Sphingolipid signaling pathway, Toxoplasmosis, Tuberculosis, Small cell lung cancer D10679 Venetoclax [1] 28
40 RELA [12] Sphingolipid signaling pathway, Toll-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Small cell lung cancer D12181 Edasalonexent [1] 113
41 RXRA [5] Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02754 Acitretin [1] 37
42 RXRA [5] Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02815 Alitretinoin [1] 49
43 RXRA [5] Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D03106 Bexarotene [2] 13, 75
44 RXRB [5] Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02754 Acitretin [1] 37
45 RXRB [5] Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02815 Alitretinoin [1] 49
46 RXRB [5] Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D03106 Bexarotene [2] 13, 75
47 RXRG [5] Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02754 Acitretin [1] 37
48 RXRG [5] Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D02815 Alitretinoin [1] 49
49 RXRG [5] Th17 cell differentiation, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Thyroid cancer, Small cell lung cancer D03106 Bexarotene [2] 13, 75
50 CASP9 [6] VEGF signaling pathway, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, Small cell lung cancer, Viral myocarditis D11195 Rimiducid [6] 19, 60, 65, 284, 285, 326