Target Gene/Pathway Pathway / Gene


Search results


No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CA5B [2] Nitrogen metabolism, Metabolic pathways D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
2 CA5B [2] Nitrogen metabolism, Metabolic pathways D00653 Dorzolamide [1] 90
3 CA5B [2] Nitrogen metabolism, Metabolic pathways D01196 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
4 CA5B [2] Nitrogen metabolism, Metabolic pathways D07871 Dorzolamide [1] 90
5 ADRA2A [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction D02076 Brimonidine [2] 13, 90
6 ADRA2A [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction D07540 Brimonidine [2] 13, 90
7 ADRA2B [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction D02076 Brimonidine [2] 13, 90
8 ADRA2B [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction D07540 Brimonidine [2] 13, 90
9 ADRA2C [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction D02076 Brimonidine [2] 13, 90
10 ADRA2C [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction D07540 Brimonidine [2] 13, 90
11 DDC [9] Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Cocaine addiction, Amphetamine addiction, Alcoholism D00558 Carbidopa [9] 2, 4, 6, 13, 17, 90, 140, 164, 201
12 DRD1 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism D00059 Levodopa [8] 2, 4, 6, 17, 90, 140, 164, 201
13 DRD2 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism D00059 Levodopa [8] 2, 4, 6, 17, 90, 140, 164, 201
14 DRD3 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse D00059 Levodopa [8] 2, 4, 6, 17, 90, 140, 164, 201
15 DRD4 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse D00059 Levodopa [8] 2, 4, 6, 17, 90, 140, 164, 201
16 DRD5 [4] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopaminergic synapse D00059 Levodopa [8] 2, 4, 6, 17, 90, 140, 164, 201
17 ABAT [7] Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism, Metabolic pathways, GABAergic synapse D00399 Valproic acid [17] 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
18 CA14 [2] Nitrogen metabolism, Metabolic pathways D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
19 CA14 [2] Nitrogen metabolism, Metabolic pathways D00653 Dorzolamide [1] 90
20 CA14 [2] Nitrogen metabolism, Metabolic pathways D01196 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
21 CA14 [2] Nitrogen metabolism, Metabolic pathways D07871 Dorzolamide [1] 90
22 GAD1 [7] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, Metabolic pathways, GABAergic synapse, Type I diabetes mellitus D00399 Valproic acid [17] 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
23 GAD2 [7] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, Metabolic pathways, GABAergic synapse, Type I diabetes mellitus D00399 Valproic acid [17] 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
24 NR3C1 [1] Neuroactive ligand-receptor interaction D00244 Betamethasone [3] 90, 96, 235
25 NR3C1 [1] Neuroactive ligand-receptor interaction D00292 Dexamethasone [10] 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
26 NR3C1 [1] Neuroactive ligand-receptor interaction D00385 Triamcinolone [6] 90, 96, 107, 162, 226, 298
27 NR3C1 [1] Neuroactive ligand-receptor interaction D00972 Betamethasone [3] 90, 96, 235
28 NR3C1 [1] Neuroactive ligand-receptor interaction D00975 Dexamethasone [10] 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
29 NR3C1 [1] Neuroactive ligand-receptor interaction D00983 Triamcinolone [6] 90, 96, 107, 162, 226, 298
30 NR3C1 [1] Neuroactive ligand-receptor interaction D00984 Triamcinolone [6] 90, 96, 107, 162, 226, 298
31 NR3C1 [1] Neuroactive ligand-receptor interaction D00985 Triamcinolone [6] 90, 96, 107, 162, 226, 298
32 NR3C1 [1] Neuroactive ligand-receptor interaction D01357 Betamethasone [3] 90, 96, 235
33 NR3C1 [1] Neuroactive ligand-receptor interaction D01402 Betamethasone [3] 90, 96, 235
34 NR3C1 [1] Neuroactive ligand-receptor interaction D01510 Dexamethasone [10] 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
35 NR3C1 [1] Neuroactive ligand-receptor interaction D01615 Dexamethasone [10] 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
36 NR3C1 [1] Neuroactive ligand-receptor interaction D01632 Dexamethasone [10] 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
37 NR3C1 [1] Neuroactive ligand-receptor interaction D01637 Betamethasone [3] 90, 96, 235
38 NR3C1 [1] Neuroactive ligand-receptor interaction D01825 Fluocinolone acetonide [1] 90
39 NR3C1 [1] Neuroactive ligand-receptor interaction D01948 Dexamethasone [10] 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
40 NR3C1 [1] Neuroactive ligand-receptor interaction D02032 Betamethasone [3] 90, 96, 235
41 NR3C1 [1] Neuroactive ligand-receptor interaction D02174 Dexamethasone [10] 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
42 NR3C1 [1] Neuroactive ligand-receptor interaction D02286 Betamethasone [3] 90, 96, 235
43 NR3C1 [1] Neuroactive ligand-receptor interaction D02591 Dexamethasone [10] 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
44 NR3C1 [1] Neuroactive ligand-receptor interaction D02592 Dexamethasone [10] 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
45 NR3C1 [1] Neuroactive ligand-receptor interaction D06216 Triamcinolone [6] 90, 96, 107, 162, 226, 298
46 CA13 [2] Nitrogen metabolism, Metabolic pathways D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
47 CA13 [2] Nitrogen metabolism, Metabolic pathways D00653 Dorzolamide [1] 90
48 CA13 [2] Nitrogen metabolism, Metabolic pathways D01196 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
49 CA13 [2] Nitrogen metabolism, Metabolic pathways D07871 Dorzolamide [1] 90
50 MTNR1A [2] Neuroactive ligand-receptor interaction, Circadian entrainment D08170 Melatonin [12] 6, 8, 13, 37, 46, 49, 90, 97, 144, 145, 149, 202
51 MTNR1B [2] Neuroactive ligand-receptor interaction, Circadian entrainment D08170 Melatonin [12] 6, 8, 13, 37, 46, 49, 90, 97, 144, 145, 149, 202
52 NGFR [8] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Apoptosis - multiple species, Neurotrophin signaling pathway, Transcriptional misregulation in cancer D11028 Cenegermin [2] 53, 90
53 PGF [6] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Pathways in cancer D09574 Aflibercept [2] 90, 166
54 PPP3CA [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
55 PPP3CB [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
56 PPP3CC [33] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Dopaminergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
57 PPP3R1 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
58 PPP3R2 [32] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Oocyte meiosis, Cellular senescence, Wnt signaling pathway, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Glucagon signaling pathway, Renin secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis D00184 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
59 PTGFR [3] Calcium signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction D08661 Unoprostone [1] 90
60 RARA [5] Th17 cell differentiation, Estrogen signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia D06543 Vitamin A [3] 13, 53, 90
61 RARB [4] Pathways in cancer, Small cell lung cancer, Non-small cell lung cancer, Gastric cancer D06543 Vitamin A [3] 13, 53, 90
62 VEGFA [24] EGFR tyrosine kinase inhibitor resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Focal adhesion, Relaxin signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Renal cell carcinoma, Pancreatic cancer, Bladder cancer, Rheumatoid arthritis, Fluid shear stress and atherosclerosis D09574 Aflibercept [2] 90, 166
63 VEGFB [9] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Relaxin signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Pathways in cancer D09574 Aflibercept [2] 90, 166
64 CA1 [2] Nitrogen metabolism, Metabolic pathways D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
65 CA1 [2] Nitrogen metabolism, Metabolic pathways D00653 Dorzolamide [1] 90
66 CA1 [2] Nitrogen metabolism, Metabolic pathways D01196 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
67 CA1 [2] Nitrogen metabolism, Metabolic pathways D07871 Dorzolamide [1] 90
68 CA2 [7] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
69 CA2 [7] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion D00653 Dorzolamide [1] 90
70 CA2 [7] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion D01196 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
71 CA2 [7] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion D07871 Dorzolamide [1] 90
72 CA3 [2] Nitrogen metabolism, Metabolic pathways D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
73 CA3 [2] Nitrogen metabolism, Metabolic pathways D00653 Dorzolamide [1] 90
74 CA3 [2] Nitrogen metabolism, Metabolic pathways D01196 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
75 CA3 [2] Nitrogen metabolism, Metabolic pathways D07871 Dorzolamide [1] 90
76 CA4 [3] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
77 CA4 [3] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation D00653 Dorzolamide [1] 90
78 CA4 [3] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation D01196 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
79 CA4 [3] Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation D07871 Dorzolamide [1] 90
80 CA5A [2] Nitrogen metabolism, Metabolic pathways D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
81 CA5A [2] Nitrogen metabolism, Metabolic pathways D00653 Dorzolamide [1] 90
82 CA5A [2] Nitrogen metabolism, Metabolic pathways D01196 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
83 CA5A [2] Nitrogen metabolism, Metabolic pathways D07871 Dorzolamide [1] 90
84 CA6 [2] Nitrogen metabolism, Metabolic pathways D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
85 CA6 [2] Nitrogen metabolism, Metabolic pathways D00653 Dorzolamide [1] 90
86 CA6 [2] Nitrogen metabolism, Metabolic pathways D01196 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
87 CA6 [2] Nitrogen metabolism, Metabolic pathways D07871 Dorzolamide [1] 90
88 CA7 [2] Nitrogen metabolism, Metabolic pathways D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
89 CA7 [2] Nitrogen metabolism, Metabolic pathways D00653 Dorzolamide [1] 90
90 CA7 [2] Nitrogen metabolism, Metabolic pathways D01196 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
91 CA7 [2] Nitrogen metabolism, Metabolic pathways D07871 Dorzolamide [1] 90
92 CA8 [2] Nitrogen metabolism, Metabolic pathways D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
93 CA8 [2] Nitrogen metabolism, Metabolic pathways D00653 Dorzolamide [1] 90
94 CA8 [2] Nitrogen metabolism, Metabolic pathways D01196 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
95 CA8 [2] Nitrogen metabolism, Metabolic pathways D07871 Dorzolamide [1] 90
96 CA9 [2] Nitrogen metabolism, Metabolic pathways D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
97 CA9 [2] Nitrogen metabolism, Metabolic pathways D00653 Dorzolamide [1] 90
98 CA9 [2] Nitrogen metabolism, Metabolic pathways D01196 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
99 CA9 [2] Nitrogen metabolism, Metabolic pathways D07871 Dorzolamide [1] 90
100 CA12 [2] Nitrogen metabolism, Metabolic pathways D00218 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
101 CA12 [2] Nitrogen metabolism, Metabolic pathways D00653 Dorzolamide [1] 90
102 CA12 [2] Nitrogen metabolism, Metabolic pathways D01196 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230
103 CA12 [2] Nitrogen metabolism, Metabolic pathways D07871 Dorzolamide [1] 90
104 CACNA1C [34] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Taste transduction, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy D01908 Nilvadipine [1] 90
105 CACNA1D [35] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cellular senescence, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Tight junction, Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome, Growth hormone synthesis, secretion and action, Carbohydrate digestion and absorption, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy D01908 Nilvadipine [1] 90
106 CACNA1F [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy D01908 Nilvadipine [1] 90
107 CACNA1S [27] MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Retrograde endocannabinoid signaling, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy D01908 Nilvadipine [1] 90
108 ALDH5A1 [3] Alanine, aspartate and glutamate metabolism, Butanoate metabolism, Metabolic pathways D00399 Valproic acid [17] 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
109 PDE5A [3] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway D02229 Sildenafil [17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
110 PDE5A [3] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway D08514 Sildenafil [17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
111 CACNA1I [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome D00399 Valproic acid [17] 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
112 CACNA1H [7] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome D00399 Valproic acid [17] 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
113 CACNA1G [8] MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Type II diabetes mellitus, Cushing syndrome D00399 Valproic acid [17] 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331