Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CHRM1 [1] Regulation of actin cytoskeleton D00113 Atropine [2] 2, 299
2 CHRM1 [1] Regulation of actin cytoskeleton D00138 Scopolamine [1] 2
3 CHRM1 [1] Regulation of actin cytoskeleton D00270 Chlorpromazine [1] 254
4 CHRM1 [1] Regulation of actin cytoskeleton D00397 Tropicamide [3] 6, 13, 19
5 CHRM1 [1] Regulation of actin cytoskeleton D00465 Oxybutynin [3] 6, 13, 53
6 CHRM1 [1] Regulation of actin cytoskeleton D00481 Propantheline [1] 26
7 CHRM1 [1] Regulation of actin cytoskeleton D00722 Oxybutynin [3] 6, 13, 53
8 CHRM1 [1] Regulation of actin cytoskeleton D00765 Rocuronium [1] 296
9 CHRM1 [1] Regulation of actin cytoskeleton D00787 Trihexyphenidyl [2] 5, 6
10 CHRM1 [1] Regulation of actin cytoskeleton D00789 Chlorpromazine [1] 254
11 CHRM1 [1] Regulation of actin cytoskeleton D01000 Bethanechol [1] 98
12 CHRM1 [1] Regulation of actin cytoskeleton D01077 Atropine [2] 2, 299
13 CHRM1 [1] Regulation of actin cytoskeleton D02069 Atropine [2] 2, 299
14 CHRM1 [1] Regulation of actin cytoskeleton D02212 Ipratropium [2] 6, 86
15 CHRM1 [1] Regulation of actin cytoskeleton D03011 Atropine [2] 2, 299
16 CHRM1 [1] Regulation of actin cytoskeleton D03274 Chlorpromazine [1] 254
17 CHRM1 [1] Regulation of actin cytoskeleton D03814 Atropine [2] 2, 299
18 CHRM1 [1] Regulation of actin cytoskeleton D04034 Chlorpromazine [1] 254
19 CHRM1 [1] Regulation of actin cytoskeleton D08441 Propiverine [1] 226
20 CHRM1 [1] Regulation of actin cytoskeleton D08638 Trihexyphenidyl [2] 5, 6
21 CHRM1 [1] Regulation of actin cytoskeleton D11383 Blarcamesine [1] 156
22 CHRM2 [1] Regulation of actin cytoskeleton D00113 Atropine [2] 2, 299
23 CHRM2 [1] Regulation of actin cytoskeleton D00138 Scopolamine [1] 2
24 CHRM2 [1] Regulation of actin cytoskeleton D00270 Chlorpromazine [1] 254
25 CHRM2 [1] Regulation of actin cytoskeleton D00397 Tropicamide [3] 6, 13, 19
26 CHRM2 [1] Regulation of actin cytoskeleton D00465 Oxybutynin [3] 6, 13, 53
27 CHRM2 [1] Regulation of actin cytoskeleton D00481 Propantheline [1] 26
28 CHRM2 [1] Regulation of actin cytoskeleton D00525 Pilocarpine [3] 6, 53, 299
29 CHRM2 [1] Regulation of actin cytoskeleton D00722 Oxybutynin [3] 6, 13, 53
30 CHRM2 [1] Regulation of actin cytoskeleton D00765 Rocuronium [1] 296
31 CHRM2 [1] Regulation of actin cytoskeleton D00787 Trihexyphenidyl [2] 5, 6
32 CHRM2 [1] Regulation of actin cytoskeleton D00789 Chlorpromazine [1] 254
33 CHRM2 [1] Regulation of actin cytoskeleton D01000 Bethanechol [1] 98
34 CHRM2 [1] Regulation of actin cytoskeleton D01077 Atropine [2] 2, 299
35 CHRM2 [1] Regulation of actin cytoskeleton D02069 Atropine [2] 2, 299
36 CHRM2 [1] Regulation of actin cytoskeleton D02200 Pilocarpine [3] 6, 53, 299
37 CHRM2 [1] Regulation of actin cytoskeleton D02212 Ipratropium [2] 6, 86
38 CHRM2 [1] Regulation of actin cytoskeleton D03011 Atropine [2] 2, 299
39 CHRM2 [1] Regulation of actin cytoskeleton D03274 Chlorpromazine [1] 254
40 CHRM2 [1] Regulation of actin cytoskeleton D03814 Atropine [2] 2, 299
41 CHRM2 [1] Regulation of actin cytoskeleton D04034 Chlorpromazine [1] 254
42 CHRM2 [1] Regulation of actin cytoskeleton D05478 Pilocarpine [3] 6, 53, 299
43 CHRM2 [1] Regulation of actin cytoskeleton D07226 Fesoterodine [1] 6
44 CHRM2 [1] Regulation of actin cytoskeleton D08441 Propiverine [1] 226
45 CHRM2 [1] Regulation of actin cytoskeleton D08638 Trihexyphenidyl [2] 5, 6
46 CHRM2 [1] Regulation of actin cytoskeleton D11383 Blarcamesine [1] 156
47 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00113 Atropine [2] 2, 299
48 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00138 Scopolamine [1] 2
49 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00270 Chlorpromazine [1] 254
50 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00397 Tropicamide [3] 6, 13, 19
51 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00465 Oxybutynin [3] 6, 13, 53
52 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00481 Propantheline [1] 26
53 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00525 Pilocarpine [3] 6, 53, 299
54 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00646 Tolterodine [2] 17, 53
55 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00661 Cevimeline [1] 53
56 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00722 Oxybutynin [3] 6, 13, 53
57 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00765 Rocuronium [1] 296
58 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00787 Trihexyphenidyl [2] 5, 6
59 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00789 Chlorpromazine [1] 254
60 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D01000 Bethanechol [1] 98
61 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D01077 Atropine [2] 2, 299
62 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D01148 Tolterodine [2] 17, 53
63 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D01269 Solifenacin [3] 6, 13, 53
64 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D01699 Darifenacin [2] 6, 13
65 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D02069 Atropine [2] 2, 299
66 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D02200 Pilocarpine [3] 6, 53, 299
67 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D02212 Ipratropium [2] 6, 86
68 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D03011 Atropine [2] 2, 299
69 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D03274 Chlorpromazine [1] 254
70 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D03654 Darifenacin [2] 6, 13
71 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D03814 Atropine [2] 2, 299
72 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D04034 Chlorpromazine [1] 254
73 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D05478 Pilocarpine [3] 6, 53, 299
74 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D07226 Fesoterodine [1] 6
75 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D07667 Cevimeline [1] 53
76 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D08441 Propiverine [1] 226
77 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D08522 Solifenacin [3] 6, 13, 53
78 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D08638 Trihexyphenidyl [2] 5, 6
79 CHRM3 [3] Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D11383 Blarcamesine [1] 156
80 CHRM4 [1] Regulation of actin cytoskeleton D00113 Atropine [2] 2, 299
81 CHRM4 [1] Regulation of actin cytoskeleton D00138 Scopolamine [1] 2
82 CHRM4 [1] Regulation of actin cytoskeleton D00270 Chlorpromazine [1] 254
83 CHRM4 [1] Regulation of actin cytoskeleton D00397 Tropicamide [3] 6, 13, 19
84 CHRM4 [1] Regulation of actin cytoskeleton D00465 Oxybutynin [3] 6, 13, 53
85 CHRM4 [1] Regulation of actin cytoskeleton D00481 Propantheline [1] 26
86 CHRM4 [1] Regulation of actin cytoskeleton D00722 Oxybutynin [3] 6, 13, 53
87 CHRM4 [1] Regulation of actin cytoskeleton D00765 Rocuronium [1] 296
88 CHRM4 [1] Regulation of actin cytoskeleton D00787 Trihexyphenidyl [2] 5, 6
89 CHRM4 [1] Regulation of actin cytoskeleton D00789 Chlorpromazine [1] 254
90 CHRM4 [1] Regulation of actin cytoskeleton D01000 Bethanechol [1] 98
91 CHRM4 [1] Regulation of actin cytoskeleton D01077 Atropine [2] 2, 299
92 CHRM4 [1] Regulation of actin cytoskeleton D02069 Atropine [2] 2, 299
93 CHRM4 [1] Regulation of actin cytoskeleton D02212 Ipratropium [2] 6, 86
94 CHRM4 [1] Regulation of actin cytoskeleton D03011 Atropine [2] 2, 299
95 CHRM4 [1] Regulation of actin cytoskeleton D03274 Chlorpromazine [1] 254
96 CHRM4 [1] Regulation of actin cytoskeleton D03814 Atropine [2] 2, 299
97 CHRM4 [1] Regulation of actin cytoskeleton D04034 Chlorpromazine [1] 254
98 CHRM4 [1] Regulation of actin cytoskeleton D08441 Propiverine [1] 226
99 CHRM4 [1] Regulation of actin cytoskeleton D08638 Trihexyphenidyl [2] 5, 6
100 CHRM4 [1] Regulation of actin cytoskeleton D11383 Blarcamesine [1] 156
101 CHRM5 [1] Regulation of actin cytoskeleton D00113 Atropine [2] 2, 299
102 CHRM5 [1] Regulation of actin cytoskeleton D00138 Scopolamine [1] 2
103 CHRM5 [1] Regulation of actin cytoskeleton D00270 Chlorpromazine [1] 254
104 CHRM5 [1] Regulation of actin cytoskeleton D00397 Tropicamide [3] 6, 13, 19
105 CHRM5 [1] Regulation of actin cytoskeleton D00465 Oxybutynin [3] 6, 13, 53
106 CHRM5 [1] Regulation of actin cytoskeleton D00481 Propantheline [1] 26
107 CHRM5 [1] Regulation of actin cytoskeleton D00722 Oxybutynin [3] 6, 13, 53
108 CHRM5 [1] Regulation of actin cytoskeleton D00765 Rocuronium [1] 296
109 CHRM5 [1] Regulation of actin cytoskeleton D00787 Trihexyphenidyl [2] 5, 6
110 CHRM5 [1] Regulation of actin cytoskeleton D00789 Chlorpromazine [1] 254
111 CHRM5 [1] Regulation of actin cytoskeleton D01000 Bethanechol [1] 98
112 CHRM5 [1] Regulation of actin cytoskeleton D01077 Atropine [2] 2, 299
113 CHRM5 [1] Regulation of actin cytoskeleton D02069 Atropine [2] 2, 299
114 CHRM5 [1] Regulation of actin cytoskeleton D02212 Ipratropium [2] 6, 86
115 CHRM5 [1] Regulation of actin cytoskeleton D03011 Atropine [2] 2, 299
116 CHRM5 [1] Regulation of actin cytoskeleton D03274 Chlorpromazine [1] 254
117 CHRM5 [1] Regulation of actin cytoskeleton D03814 Atropine [2] 2, 299
118 CHRM5 [1] Regulation of actin cytoskeleton D04034 Chlorpromazine [1] 254
119 CHRM5 [1] Regulation of actin cytoskeleton D08441 Propiverine [1] 226
120 CHRM5 [1] Regulation of actin cytoskeleton D08638 Trihexyphenidyl [2] 5, 6
121 CHRM5 [1] Regulation of actin cytoskeleton D11383 Blarcamesine [1] 156
122 EGFR [3] Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D01977 Gefitinib [1] 75
123 EGFR [3] Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D03455 Cetuximab [5] 34, 51, 86, 89, 331
124 EGFR [3] Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D04023 Erlotinib [1] 94
125 EGFR [3] Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D04024 Lapatinib [3] 34, 74, 75
126 EGFR [3] Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D07907 Erlotinib [1] 94
127 EGFR [3] Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D08108 Lapatinib [3] 34, 74, 75
128 EGFR [3] Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D11251 Icotinib [1] 34
129 EGFR [3] Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D11772 Tesevatinib [1] 67
130 F2 [1] Regulation of actin cytoskeleton D06410 Thrombomodulin Alfa [1] 85
131 F2 [1] Regulation of actin cytoskeleton D07144 Dabigatran etexilate [1] 51
132 F2 [1] Regulation of actin cytoskeleton D09707 Dabigatran [4] 51, 85, 91, 124
133 FGFR1 [3] Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton D10481 Nintedanib [5] 51, 85, 89, 227, 228
134 FGFR1 [3] Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton D11589 Infigratinib [1] 276
135 FGFR3 [2] Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D10481 Nintedanib [5] 51, 85, 89, 227, 228
136 FGFR3 [2] Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D11589 Infigratinib [1] 276
137 FGFR2 [2] Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D05338 Palifermin [5] 13, 36, 38, 39, 65
138 FGFR2 [2] Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D10481 Nintedanib [5] 51, 85, 89, 227, 228
139 FGFR2 [2] Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D11589 Infigratinib [1] 276
140 ITGA4 [2] Regulation of actin cytoskeleton, Yersinia infection D06590 Firategrast [1] 13
141 ITGA4 [2] Regulation of actin cytoskeleton, Yersinia infection D06886 Natalizumab [6] 13, 15, 25, 46, 63, 96
142 ITGA4 [2] Regulation of actin cytoskeleton, Yersinia infection D08083 Vedolizumab [3] 94, 96, 97
143 ITGA4 [2] Regulation of actin cytoskeleton, Yersinia infection D10540 Abrilumab [2] 96, 97
144 ITGAL [4] Regulation of actin cytoskeleton, Staphylococcus aureus infection, Rheumatoid arthritis, Viral myocarditis D03959 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96
145 ITGB7 [2] Regulation of actin cytoskeleton, Transcriptional misregulation in cancer D08083 Vedolizumab [3] 94, 96, 97
146 ITGB7 [2] Regulation of actin cytoskeleton, Transcriptional misregulation in cancer D09901 Etrolizumab [2] 96, 97
147 ITGB7 [2] Regulation of actin cytoskeleton, Transcriptional misregulation in cancer D10540 Abrilumab [2] 96, 97
148 PDGFRA [1] Regulation of actin cytoskeleton D01441 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
149 PDGFRA [1] Regulation of actin cytoskeleton D06402 Sunitinib [2] 28, 34
150 PDGFRA [1] Regulation of actin cytoskeleton D08066 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
151 PDGFRA [1] Regulation of actin cytoskeleton D08552 Sunitinib [2] 28, 34
152 PDGFRA [1] Regulation of actin cytoskeleton D08953 Nilotinib [5] 6, 8, 34, 51, 86
153 PDGFRA [1] Regulation of actin cytoskeleton D10481 Nintedanib [5] 51, 85, 89, 227, 228
154 PDGFRB [1] Regulation of actin cytoskeleton D03658 Dasatinib [2] 51, 85
155 PDGFRB [1] Regulation of actin cytoskeleton D06272 Sorafenib [2] 34, 86
156 PDGFRB [1] Regulation of actin cytoskeleton D06402 Sunitinib [2] 28, 34
157 PDGFRB [1] Regulation of actin cytoskeleton D06414 Dasatinib [2] 51, 85
158 PDGFRB [1] Regulation of actin cytoskeleton D08524 Sorafenib [2] 34, 86
159 PDGFRB [1] Regulation of actin cytoskeleton D08552 Sunitinib [2] 28, 34
160 PDGFRB [1] Regulation of actin cytoskeleton D08953 Nilotinib [5] 6, 8, 34, 51, 86
161 PDGFRB [1] Regulation of actin cytoskeleton D10481 Nintedanib [5] 51, 85, 89, 227, 228
162 PIK3CA [18] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib [2] 53, 65
163 PIK3CB [18] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib [2] 53, 65
164 PIK3CD [18] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib [2] 53, 65
165 PIK3CD [18] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11437 Parsaclisib [3] 35, 53, 61
166 MAP2K1 [15] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib [1] 34
167 MAP2K1 [15] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10175 Trametinib [4] 2, 34, 279, 280
168 MAP2K1 [15] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib [1] 280
169 MAP2K1 [15] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib [1] 34
170 MAP2K2 [13] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib [1] 34
171 MAP2K2 [13] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10175 Trametinib [4] 2, 34, 279, 280
172 MAP2K2 [13] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib [1] 280
173 MAP2K2 [13] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib [1] 34
174 RAF1 [12] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Renal cell carcinoma D06272 Sorafenib [2] 34, 86
175 RAF1 [12] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Renal cell carcinoma D08524 Sorafenib [2] 34, 86
176 ROCK1 [7] Sphingolipid signaling pathway, Vascular smooth muscle contraction, TGF-beta signaling pathway, Tight junction, Regulation of actin cytoskeleton, Shigellosis, Yersinia infection D07941 Fasudil [4] 2, 5, 7, 51
177 SRC [9] VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D03252 Bosutinib [2] 2, 67
178 SRC [9] VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D03658 Dasatinib [2] 51, 85
179 SRC [9] VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D06414 Dasatinib [2] 51, 85
180 SRC [9] VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D09664 Saracatinib [3] 6, 89, 272
181 BRAF [5] Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Renal cell carcinoma, Thyroid cancer D06272 Sorafenib [2] 34, 86
182 BRAF [5] Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Renal cell carcinoma, Thyroid cancer D08524 Sorafenib [2] 34, 86
183 BRAF [5] Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Renal cell carcinoma, Thyroid cancer D10064 Dabrafenib [1] 34
184 CXCR4 [2] Viral protein interaction with cytokine and cytokine receptor, Regulation of actin cytoskeleton D08971 Plerixafor [6] 19, 20, 51, 65, 285, 299
185 FGF23 [1] Regulation of actin cytoskeleton D10913 Burosumab [1] 238
186 ROCK2 [8] Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Regulation of actin cytoskeleton, Shigellosis, Salmonella infection, Yersinia infection D07941 Fasudil [4] 2, 5, 7, 51
187 ROCK2 [8] Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Regulation of actin cytoskeleton, Shigellosis, Salmonella infection, Yersinia infection D11815 Belumosudil [1] 51