Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D01692 💬 Alfuzosin [1] 13 💬
2 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D07124 💬 Alfuzosin [1] 13 💬
3 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00636 💬 Amiodarone [2] 28, 127 💬
4 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D02910 💬 Amiodarone [2] 28, 127 💬
5 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
6 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
7 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D02349 💬 Dipivefrin [1]  6  💬
8 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00608 💬 Doxazosin [2] 57, 67 💬
9 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D07874 💬 Doxazosin [2] 57, 67 💬
10 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
11 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00124 💬 Ephedrine [1] 11 💬
12 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00095 💬 Epinephrine [3] 46, 70, 96 💬
13 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00996 💬 Epinephrine [3] 46, 70, 96 💬
14 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D02149 💬 Epinephrine [3] 46, 70, 96 💬
15 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D02268 💬 Ergoloid mesylate [2]  6 , 206 💬
16 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D08064 💬 Ifenprodil [1] 85 💬
17 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00680 💬 Methylergometrine [3] 118, 280, 288 💬
18 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D08207 💬 Methylergometrine [3] 118, 280, 288 💬
19 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D01307 💬 Midodrine [3]  6 , 17, 58 💬
20 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D08220 💬 Midodrine [3]  6 , 17, 58 💬
21 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00076 💬 Norepinephrine [1] 22 💬
22 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D05206 💬 Norepinephrine [1] 22 💬
23 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
24 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D06623 💬 Olanzapine [2]  2 ,  8  💬
25 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00511 💬 Phenylephrine [1] 22 💬
26 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D08365 💬 Phenylephrine [1] 22 💬
27 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00485 💬 Pseudoephedrine [1] 17 💬
28 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D05648 💬 Pseudoephedrine [1] 17 💬
29 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D05649 💬 Pseudoephedrine [1] 17 💬
30 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D08449 💬 Pseudoephedrine [1] 17 💬
31 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D01965 💬 Silodosin [2]  6 , 13 💬
32 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D00610 💬 Terazosin [1]  6  💬
33 AMPK signaling pathway 💬
 [1] ADRA1A 💬 D08569 💬 Terazosin [1]  6  💬
34 AMPK signaling pathway 💬
 [1] CFTR 💬 D11423 💬 Deutivacaftor [1] 299 💬
35 AMPK signaling pathway 💬
 [1] CFTR 💬 D11507 💬 Elexacaftor [1] 299 💬
36 AMPK signaling pathway 💬
 [1] CFTR 💬 D11724 💬 Galicaftor [1] 299 💬
37 AMPK signaling pathway 💬
 [1] CFTR 💬 D09916 💬 Ivacaftor [1] 299 💬
38 AMPK signaling pathway 💬
 [1] CFTR 💬 D10134 💬 Lumacaftor [1] 299 💬
39 AMPK signaling pathway 💬
 [1] CFTR 💬 D11041 💬 Tezacaftor [1] 299 💬
40 AMPK signaling pathway 💬
 [3] CPT1A, CPT1B, CPT1C 💬 D05442 💬 Perhexiline [2] 58, 272 💬
41 AMPK signaling pathway 💬
 [3] CPT1A, CPT1B, CPT1C 💬 D08340 💬 Perhexiline [2] 58, 272 💬
42 AMPK signaling pathway 💬
 [1] HMGCR 💬 D00887 💬 Atorvastatin [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬
43 AMPK signaling pathway 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬
44 AMPK signaling pathway 💬
 [1] HMGCR 💬 D00892 💬 Fluvastatin [3] 79, 218, 222 💬
45 AMPK signaling pathway 💬
 [1] HMGCR 💬 D07983 💬 Fluvastatin [3] 79, 218, 222 💬
46 AMPK signaling pathway 💬
 [1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
47 AMPK signaling pathway 💬
 [1] HMGCR 💬 D00893 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
48 AMPK signaling pathway 💬
 [1] HMGCR 💬 D08410 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
49 AMPK signaling pathway 💬
 [1] HMGCR 💬 D01915 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
50 AMPK signaling pathway 💬
 [1] HMGCR 💬 D08492 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
51 AMPK signaling pathway 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
52 AMPK signaling pathway 💬
 [1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
53 AMPK signaling pathway 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
54 AMPK signaling pathway 💬
 [1] IGF1R 💬 D04870 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
55 AMPK signaling pathway 💬
 [1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
56 AMPK signaling pathway 💬
 [1] INSR 💬 D04539 💬 Insulin detemir [1] 299 💬
57 AMPK signaling pathway 💬
 [1] INSR 💬 D03250 💬 Insulin glargine [1] 299 💬
58 AMPK signaling pathway 💬
 [1] INSR 💬 D00085 💬 Insulin human [2] 96, 156 💬
59 AMPK signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
60 AMPK signaling pathway 💬
 [1] LEPR 💬 D05014 💬 Metreleptin [1] 265 💬
61 AMPK signaling pathway 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
62 AMPK signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [41]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
63 AMPK signaling pathway 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [4] 13, 34, 89, 331 💬
64 AMPK signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
65 AMPK signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
66 AMPK signaling pathway 💬
 [1] PPARG 💬 D11603 💬 Leriglitazone [1] 20 💬
67 AMPK signaling pathway 💬
 [1] PPARG 💬 D00945 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
68 AMPK signaling pathway 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
69 AMPK signaling pathway 💬
 [1] PPARG 💬 D00596 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
70 AMPK signaling pathway 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
71 AMPK signaling pathway 💬
 [1] PPARG 💬 D11256 💬 Seladelpar [2] 93, 94 💬
72 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D00944 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
73 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [24]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬