Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
2 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
JAK2 1件: JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
3 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
4 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
5 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
6 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
7 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
8 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
9 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
SCN5A 1件: SCN5A 💬 |
Lidocaine Lidocaine 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬 |
10 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
SCN5A 1件: SCN5A 💬 |
Lidocaine hydrochloride monohydrate Lidocaine hydrochloride monohydrate 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬 |
11 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL10 4件: IL10, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
12 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
13 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
14 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
15 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
16 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
17 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
18 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
CCL2 5件: CCL2, IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
19 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
20 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
JAK2 1件: JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
21 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
22 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
23 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
24 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
25 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
26 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
27 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL1B 3件: IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
28 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
29 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
30 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
31 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
32 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
SLC6A3 1件: SLC6A3 💬 |
Armodafinil Armodafinil 💬 |
Armodafinil | 006 3件: 6 , 13, 84 💬 💬 |
33 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
SLC6A3 1件: SLC6A3 💬 |
Methylphenidate Methylphenidate 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 💬 |
34 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
MC2R 1件: MC2R 💬 |
Corticotropin Corticotropin 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬 |
35 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
36 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
IL10 2件: IL10, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
37 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
38 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
39 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
40 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
41 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
42 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
CHRNA7 1件: CHRNA7 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 3件: 6 , 13, 84 💬 💬 |
43 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
44 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
45 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
46 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
47 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
48 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
49 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
50 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL10 4件: IL10, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
51 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
52 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
53 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
54 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
55 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
56 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
57 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
58 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
SLC6A3 1件: SLC6A3 💬 |
Armodafinil Armodafinil 💬 |
Armodafinil | 006 3件: 6 , 13, 84 💬 💬 |
59 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
SLC6A3 1件: SLC6A3 💬 |
Methylphenidate Methylphenidate 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 💬 |
60 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR 1件: HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
61 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
62 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
63 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
64 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
65 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
66 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
67 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
68 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
Methotrexate Methotrexate 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬 |
69 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
70 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL1B 3件: IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
71 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
72 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
73 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
74 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
75 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
76 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
77 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
78 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
79 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
80 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
81 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
82 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
83 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
84 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
85 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
86 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
IL10 2件: IL10, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
87 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
88 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
89 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
90 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
91 | Autoimmune thyroid disease 💬 22 genes, 15 drugs (DrugBank) and 35 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
92 | Autoimmune thyroid disease 💬 22 genes, 15 drugs (DrugBank) and 35 diseases |
IL10 1件: IL10 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
93 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
94 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
95 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR 1件: HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
96 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
NR1H4 1件: NR1H4 💬 |
Ursodiol Ursodiol 💬 |
Ursodeoxycholic acid | 006 14件: 6 , 8 , 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬 💬 |
97 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 51 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
Methotrexate Methotrexate 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬 |
98 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
99 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL10 4件: IL10, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
100 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
101 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
102 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
103 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
104 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
105 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
106 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRNA7 1件: CHRNA7 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 3件: 6 , 13, 84 💬 💬 |
107 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA 1件: EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 💬 |
108 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
109 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
110 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA 1件: EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 💬 |
111 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA 1件: EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
112 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA 1件: EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
113 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MC2R 1件: MC2R 💬 |
Corticotropin Corticotropin 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬 |
114 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Roflumilast Roflumilast 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 💬 |
115 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
SSTR2 1件: SSTR2 💬 |
Octreotide Octreotide 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 💬 |
116 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
117 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A 2件: IL1A, IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
118 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
119 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
120 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA 1件: EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 💬 |
121 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
122 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
123 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 💬 |
124 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE5A 1件: PDE5A 💬 |
Tadalafil Tadalafil 💬 |
Tadalafil | 006 7件: 6 , 51, 75, 84, 86, 113, 210 💬 💬 |
125 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
CCL2 5件: CCL2, IL10, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
126 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
127 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
128 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
129 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
130 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
131 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
132 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CHRNA3 6件: CHRNA3, CHRNA4, CHRNA7, CHRNA9, CHRNB2, CHRNB4 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 3件: 6 , 13, 84 💬 💬 |
133 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
JAK2 1件: JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
134 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
135 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR 1件: VDR 💬 |
Cholecalciferol Cholecalciferol 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 💬 |
136 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR 1件: VDR 💬 |
Ergocalciferol Ergocalciferol 💬 |
Ergocalciferol | 046 6件: 46, 49, 84, 96, 97, 299 💬 💬 |
137 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
CCL2 1件: CCL2 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
138 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
CCR5 1件: CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 2件: 46, 84 💬 💬 |
139 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
JAK2 2件: JAK2, JAK3 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
140 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
141 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRNA3 6件: CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 3件: 6 , 13, 84 💬 💬 |
142 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
JAK2 1件: JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
143 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 💬 |
144 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC6A3 1件: SLC6A3 💬 |
Armodafinil Armodafinil 💬 |
Armodafinil | 006 3件: 6 , 13, 84 💬 💬 |
145 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC6A3 1件: SLC6A3 💬 |
Methylphenidate Methylphenidate 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 💬 |
146 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
147 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
SERPINC1 1件: SERPINC1 💬 |
Adomiparin Adomiparin 💬 |
Heparin | 047 11件: 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317 💬 💬 |
148 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
149 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
150 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
151 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
152 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
153 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 2件: JAK1, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
154 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
155 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
156 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
157 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
158 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
MC2R 1件: MC2R 💬 |
Corticotropin Corticotropin 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬 |
159 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MC2R 1件: MC2R 💬 |
Corticotropin Corticotropin 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬 |
160 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CCL2 6件: CCL2, IL10, IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
161 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CCR5 1件: CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 2件: 46, 84 💬 💬 |
162 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
163 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
164 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
165 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
166 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
167 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
168 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
169 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
170 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
171 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B 2件: IL1B, IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
172 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
173 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
174 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
175 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
176 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
177 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
178 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SCN1A 1件: SCN1A 💬 |
Lidocaine Lidocaine 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬 |
179 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SCN1A 1件: SCN1A 💬 |
Lidocaine hydrochloride monohydrate Lidocaine hydrochloride monohydrate 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬 |
180 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SLC6A3 1件: SLC6A3 💬 |
Armodafinil Armodafinil 💬 |
Armodafinil | 006 3件: 6 , 13, 84 💬 💬 |
181 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SLC6A3 1件: SLC6A3 💬 |
Methylphenidate Methylphenidate 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 💬 |
182 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
Mycophenolic acid Mycophenolic acid 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 💬 |
183 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6 1件: IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
184 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
185 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
186 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
187 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
188 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
VDR 1件: VDR 💬 |
Cholecalciferol Cholecalciferol 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 💬 |
189 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
VDR 1件: VDR 💬 |
Ergocalciferol Ergocalciferol 💬 |
Ergocalciferol | 046 6件: 46, 49, 84, 96, 97, 299 💬 💬 |
190 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
191 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
CCR5 1件: CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 2件: 46, 84 💬 💬 |
192 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
IL6 2件: IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
193 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
194 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
JAK1 3件: JAK1, JAK3, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
195 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
196 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
197 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
198 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
199 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
200 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
201 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
202 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
203 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
204 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
205 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
CCL2 4件: CCL2, IL1A, IL1B, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
206 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
207 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
208 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
209 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
210 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
211 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
212 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 39 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
Methotrexate Methotrexate 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬 |
213 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
IL10 2件: IL10, IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
214 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 💬 |
215 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
SSTR2 1件: SSTR2 💬 |
Octreotide Octreotide 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 💬 |
216 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
217 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
218 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
219 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
220 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
221 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
222 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
223 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
224 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
225 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
JAK2 1件: JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
226 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
227 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
SSTR2 1件: SSTR2 💬 |
Octreotide Octreotide 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 💬 |
228 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
229 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
230 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
231 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
232 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
MS4A1 1件: MS4A1 💬 |
Rituximab Rituximab 💬 |
Rituximab | 011 48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 💬 |
233 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
234 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84 |