Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 PDE5A 3件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬 D00302 Dipyridamole 6件: 46, 49, 51, 66, 96, 224
2 PDE5A 3件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬 D00528 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
3 PDE5A 3件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬 D01453 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
4 PDE5A 3件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬 D02008 Tadalafil 7件: 6, 51, 75, 84, 86, 113, 210
5 PDE5A 3件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬 D02229 Sildenafil 17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
6 PDE5A 3件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬 D02731 Vardenafil 3件: 13, 86, 299
7 PDE5A 3件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬 D03260 Vardenafil 3件: 13, 86, 299
8 PDE5A 3件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬 D08514 Sildenafil 17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
9 PDE5A 3件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬 D08668 Vardenafil 3件: 13, 86, 299
10 PDE5A 3件: Purine metabolism 💬, Metabolic pathways 💬, cGMP-PKG signaling pathway 💬 D10027 Udenafil 2件: 86, 210