Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00227 Aminophylline 1件: 63
2 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00302 Dipyridamole 6件: 46, 49, 51, 66, 96, 224
3 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00371 Theophylline 2件: 236, 299
4 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00528 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
5 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D00718 Flavoxate 1件: 226
6 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01385 Ibudilast 2件: 2, 13
7 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01453 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
8 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01712 Theophylline 2件: 236, 299
9 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D01783 Rolipram 2件: 8, 13
10 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D02017 Theophylline 2件: 236, 299
11 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D05429 Aminophylline 1件: 63
12 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D05744 Roflumilast 2件: 84, 299
13 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D06103 Theophylline 2件: 236, 299
14 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D06104 Theophylline 2件: 236, 299
15 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D07546 Bucladesine 1件: 246
16 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D07961 Flavoxate 1件: 226
17 PDE4A 5件: Purine metabolism 💬, Metabolic pathways 💬, cAMP signaling pathway 💬, Parathyroid hormone synthesis, secretion and action 💬, Morphine addiction 💬 D08860 Apremilast 7件: 46, 50, 56, 97, 107, 162, 271