Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Apelin signaling pathway 💬
1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
2 Apelin signaling pathway 💬
1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
3 Apelin signaling pathway 💬
1件: AGTR1 💬 Candesartan 💬 Candesartan 2件: 58, 67 💬
4 Apelin signaling pathway 💬
1件: AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil 1件: 67 💬
5 Apelin signaling pathway 💬
1件: AGTR1 💬 Irbesartan 💬 Irbesartan 4件: 66, 167, 168, 222 💬
6 Apelin signaling pathway 💬
1件: AGTR1 💬 Losartan 💬 Losartan 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
7 Apelin signaling pathway 💬
1件: AGTR1 💬 Sparsentan 💬 Sparsentan 3件: 66, 218, 222 💬
8 Apelin signaling pathway 💬
1件: AGTR1 💬 Telmisartan 💬 Telmisartan 2件: 66, 67 💬
9 Apelin signaling pathway 💬
1件: AGTR1 💬 Valsartan 💬 Valsartan 7件: 57, 58, 66, 75, 218, 222, 224 💬
10 Apelin signaling pathway 💬
1件: CCN2 💬 Pamrevlumab 💬 Pamrevlumab 2件: 85, 113 💬
11 Apelin signaling pathway 💬
2件: HDAC4, HDAC5 💬 Vorinostat 💬 Vorinostat 2件: 75, 96 💬
12 Apelin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
13 Apelin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
14 Apelin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 1件: 34 💬
15 Apelin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
16 Apelin signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 4件:  2 , 34, 279, 280 💬
17 Apelin signaling pathway 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
18 Apelin signaling pathway 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
19 Apelin signaling pathway 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬
20 Apelin signaling pathway 💬
1件: PDE3B 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
21 Apelin signaling pathway 💬
1件: PDE3B 💬 Bucladesine 💬 Bucladesine 1件: 246 💬
22 Apelin signaling pathway 💬
1件: PDE3B 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
23 Apelin signaling pathway 💬
1件: PDE3B 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
24 Apelin signaling pathway 💬
1件: PDE3B 💬 Cilostazol 💬 Cilostazol 3件: 46, 51, 70 💬
25 Apelin signaling pathway 💬
1件: PDE3B 💬 Flavoxate 💬 Flavoxate 1件: 226 💬
26 Apelin signaling pathway 💬
1件: PDE3B 💬 Ibudilast 💬 Ibudilast 2件:  2 , 13 💬
27 Apelin signaling pathway 💬
1件: PDE3B 💬 Levosimendan 💬 Levosimendan 1件:  2  💬
28 Apelin signaling pathway 💬
1件: PDE3B 💬 Milrinone 💬 Milrinone 1件: 294 💬
29 Apelin signaling pathway 💬
1件: PDE3B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
30 Apelin signaling pathway 💬
1件: PDE3B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
31 Apelin signaling pathway 💬
2件: PRKAA1, PRKAA2 💬 Metformin 💬 Metformin 25件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
32 Apelin signaling pathway 💬
1件: PRKCE 💬 Sotrastaurin 💬 Sotrastaurin 1件: 97 💬
33 Apelin signaling pathway 💬
1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬