Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
指定難病告示番号
1 Metformin 5件: METFORMIN; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine2件: D00944 (Name: Metformin hydrochloride),
D04966 (Name: Metformin)
2件: PRKAA1,
PRKAA2 💬
20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
2 Pioglitazone
(Synonym: Pioglitazone and metformin)
1件: Pioglitazone2件: D00945 ,
D08378
1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
3 Repaglinide
(Synonym: Repaglinide and Metformin Hydrochloride)
1件: Repaglinide1件: D00594 2件: ABCC8,
KCNJ11 💬
4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬3件: 6, 21, 299
4 Rosiglitazone
(Synonym: PMS-rosiglitazone-metformin)
2件: Rosiglitazone; Rosiglitazone maleate2件: D00596 ,
D08491
1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬5件: 46, 75, 97, 222, 265
5 Sitagliptin
(Synonym: Sitagliptin Phosphate/Metformin Hydrochloride)
1件: Sitagliptin1件: D08516 1件: DPP4 💬1件: Protein digestion and absorption 💬4件: 6, 75, 233, 299