Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Axon guidance 💬
1件: ABL1 💬 D01441 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
2 Axon guidance 💬
1件: ABL1 💬 D08066 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
3 Axon guidance 💬
1件: ABL1 💬 D08953 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
4 Axon guidance 💬
4件: ABL1, EPHA2, FYN, SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
5 Axon guidance 💬
4件: ABL1, EPHA2, FYN, SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
6 Axon guidance 💬
2件: ABL1, SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
7 Axon guidance 💬
2件: ABL1, SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
8 Axon guidance 💬
1件: BMPR2 💬 D03779 💬 Dibotermin alfa 1件: 34 💬
9 Axon guidance 💬
1件: CXCR4 💬 D08971 💬 Plerixafor 6件: 19, 20, 51, 65, 285, 299 💬
10 Axon guidance 💬
1件: EPHB4 💬 D11772 💬 Tesevatinib 1件: 67 💬
11 Axon guidance 💬
1件: MET 💬 D10062 💬 Cabozantinib 1件: 34 💬
12 Axon guidance 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
13 Axon guidance 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
14 Axon guidance 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
15 Axon guidance 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus 1件: 160 💬
16 Axon guidance 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
17 Axon guidance 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
18 Axon guidance 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin 1件: 222 💬
19 Axon guidance 💬
1件: RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
20 Axon guidance 💬
1件: RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
21 Axon guidance 💬
1件: RGMA 💬 D11355 💬 Elezanumab 1件: 13 💬
22 Axon guidance 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
23 Axon guidance 💬
1件: ROCK2 💬 D11815 💬 Belumosudil 1件: 51 💬
24 Axon guidance 💬
1件: SMO 💬 D10671 💬 Taladegib 1件: 85 💬
25 Axon guidance 💬
1件: SMO 💬 D09992 💬 Vismodegib 1件: 85 💬