Target Gene/Pathway PATHWAY / GENE


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No. KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG DRUG DrugBank 指定難病告示番号
1 SRC 42件: EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, ErbB signaling pathway 💬, Rap1 signaling pathway 💬, Chemokine signaling pathway 💬, Mitophagy - animal 💬, Endocytosis 💬, Axon guidance 💬, VEGF signaling pathway 💬, Focal adhesion 💬, Adherens junction 💬, Tight junction 💬, Gap junction 💬, Platelet activation 💬, Neutrophil extracellular trap formation 💬, C-type lectin receptor signaling pathway 💬, GABAergic synapse 💬, Inflammatory mediator regulation of TRP channels 💬, Regulation of actin cytoskeleton 💬, GnRH signaling pathway 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Oxytocin signaling pathway 💬, Relaxin signaling pathway 💬, Bacterial invasion of epithelial cells 💬, Epithelial cell signaling in Helicobacter pylori infection 💬, Pathogenic Escherichia coli infection 💬, Shigellosis 💬, Yersinia infection 💬, Tuberculosis 💬, Hepatitis B 💬, Human cytomegalovirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Viral carcinogenesis 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Chemical carcinogenesis - reactive oxygen species 💬, Bladder cancer 💬, Lipid and atherosclerosis 💬, Fluid shear stress and atherosclerosis 💬 D03252 Bosutinib 2件: 2, 67
2 SRC 42件: EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, ErbB signaling pathway 💬, Rap1 signaling pathway 💬, Chemokine signaling pathway 💬, Mitophagy - animal 💬, Endocytosis 💬, Axon guidance 💬, VEGF signaling pathway 💬, Focal adhesion 💬, Adherens junction 💬, Tight junction 💬, Gap junction 💬, Platelet activation 💬, Neutrophil extracellular trap formation 💬, C-type lectin receptor signaling pathway 💬, GABAergic synapse 💬, Inflammatory mediator regulation of TRP channels 💬, Regulation of actin cytoskeleton 💬, GnRH signaling pathway 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Oxytocin signaling pathway 💬, Relaxin signaling pathway 💬, Bacterial invasion of epithelial cells 💬, Epithelial cell signaling in Helicobacter pylori infection 💬, Pathogenic Escherichia coli infection 💬, Shigellosis 💬, Yersinia infection 💬, Tuberculosis 💬, Hepatitis B 💬, Human cytomegalovirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Viral carcinogenesis 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Chemical carcinogenesis - reactive oxygen species 💬, Bladder cancer 💬, Lipid and atherosclerosis 💬, Fluid shear stress and atherosclerosis 💬 D03658 Dasatinib 2件: 51, 85
3 SRC 42件: EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, ErbB signaling pathway 💬, Rap1 signaling pathway 💬, Chemokine signaling pathway 💬, Mitophagy - animal 💬, Endocytosis 💬, Axon guidance 💬, VEGF signaling pathway 💬, Focal adhesion 💬, Adherens junction 💬, Tight junction 💬, Gap junction 💬, Platelet activation 💬, Neutrophil extracellular trap formation 💬, C-type lectin receptor signaling pathway 💬, GABAergic synapse 💬, Inflammatory mediator regulation of TRP channels 💬, Regulation of actin cytoskeleton 💬, GnRH signaling pathway 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Oxytocin signaling pathway 💬, Relaxin signaling pathway 💬, Bacterial invasion of epithelial cells 💬, Epithelial cell signaling in Helicobacter pylori infection 💬, Pathogenic Escherichia coli infection 💬, Shigellosis 💬, Yersinia infection 💬, Tuberculosis 💬, Hepatitis B 💬, Human cytomegalovirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Viral carcinogenesis 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Chemical carcinogenesis - reactive oxygen species 💬, Bladder cancer 💬, Lipid and atherosclerosis 💬, Fluid shear stress and atherosclerosis 💬 D06414 Dasatinib 2件: 51, 85
4 SRC 42件: EGFR tyrosine kinase inhibitor resistance 💬, Endocrine resistance 💬, ErbB signaling pathway 💬, Rap1 signaling pathway 💬, Chemokine signaling pathway 💬, Mitophagy - animal 💬, Endocytosis 💬, Axon guidance 💬, VEGF signaling pathway 💬, Focal adhesion 💬, Adherens junction 💬, Tight junction 💬, Gap junction 💬, Platelet activation 💬, Neutrophil extracellular trap formation 💬, C-type lectin receptor signaling pathway 💬, GABAergic synapse 💬, Inflammatory mediator regulation of TRP channels 💬, Regulation of actin cytoskeleton 💬, GnRH signaling pathway 💬, Estrogen signaling pathway 💬, Prolactin signaling pathway 💬, Thyroid hormone signaling pathway 💬, Oxytocin signaling pathway 💬, Relaxin signaling pathway 💬, Bacterial invasion of epithelial cells 💬, Epithelial cell signaling in Helicobacter pylori infection 💬, Pathogenic Escherichia coli infection 💬, Shigellosis 💬, Yersinia infection 💬, Tuberculosis 💬, Hepatitis B 💬, Human cytomegalovirus infection 💬, Kaposi sarcoma-associated herpesvirus infection 💬, Herpes simplex virus 1 infection 💬, Viral carcinogenesis 💬, Proteoglycans in cancer 💬, Chemical carcinogenesis - receptor activation 💬, Chemical carcinogenesis - reactive oxygen species 💬, Bladder cancer 💬, Lipid and atherosclerosis 💬, Fluid shear stress and atherosclerosis 💬 D09664 Saracatinib 3件: 6, 89, 272