Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Chronic myeloid leukemia 💬
1件: ABL1 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
2 Chronic myeloid leukemia 💬
1件: ABL1 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
3 Chronic myeloid leukemia 💬
1件: ABL1 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
4 Chronic myeloid leukemia 💬
1件: ABL1 💬 D01441 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
5 Chronic myeloid leukemia 💬
1件: ABL1 💬 D08066 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
6 Chronic myeloid leukemia 💬
1件: ABL1 💬 D08953 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
7 Chronic myeloid leukemia 💬
1件: ABL1 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
8 Chronic myeloid leukemia 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
9 Chronic myeloid leukemia 💬
2件: BRAF, RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
10 Chronic myeloid leukemia 💬
2件: BRAF, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
11 Chronic myeloid leukemia 💬
2件: CDK4, CDK6 💬 D10688 💬 Abemaciclib 1件: 34 💬
12 Chronic myeloid leukemia 💬
2件: HDAC1, HDAC2 💬 D06320 💬 Vorinostat 3件: 19, 75, 96 💬
13 Chronic myeloid leukemia 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
14 Chronic myeloid leukemia 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
15 Chronic myeloid leukemia 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
16 Chronic myeloid leukemia 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
17 Chronic myeloid leukemia 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
18 Chronic myeloid leukemia 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
19 Chronic myeloid leukemia 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
20 Chronic myeloid leukemia 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
21 Chronic myeloid leukemia 💬
3件: TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab 4件: 51, 85, 222, 274 💬