Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Herpes simplex virus 1 infection 💬
1件: BCL2 💬 D10679 💬 Venetoclax 1件: 28 💬
2 Herpes simplex virus 1 infection 💬
1件: C3 💬 D11613 💬 Pegcetacoplan 3件:  2 , 62, 222 💬
3 Herpes simplex virus 1 infection 💬
1件: C5 💬 D11696 💬 Crovalimab 2件: 62, 109 💬
4 Herpes simplex virus 1 infection 💬
1件: C5 💬 D03940 💬 Eculizumab 7件: 11, 13, 14, 61, 62, 109, 222 💬
5 Herpes simplex virus 1 infection 💬
1件: C5 💬 D11473 💬 Nomacopan 3件: 62, 109, 162 💬
6 Herpes simplex virus 1 infection 💬
1件: C5 💬 D11477 💬 Pozelimab 2件: 11, 62 💬
7 Herpes simplex virus 1 infection 💬
1件: C5 💬 D11054 💬 Ravulizumab 7件:  2 , 11, 13, 50, 62, 66, 109 💬
8 Herpes simplex virus 1 infection 💬
1件: C5 💬 D11838 💬 Vilobelimab 3件: 43, 44, 269 💬
9 Herpes simplex virus 1 infection 💬
1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
10 Herpes simplex virus 1 infection 💬
4件: CCL2, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
11 Herpes simplex virus 1 infection 💬
1件: CD74 💬 D08944 💬 Milatuzumab 1件: 49 💬
12 Herpes simplex virus 1 infection 💬
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 D04318 💬 Glatiramer 4件:  2 , 13, 96, 156 💬
13 Herpes simplex virus 1 infection 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab 1件: 49 💬
14 Herpes simplex virus 1 infection 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab 1件: 49 💬
15 Herpes simplex virus 1 infection 💬
2件: IFNAR1, IFNAR2 💬 D11082 💬 Anifrolumab 2件: 46, 49 💬
16 Herpes simplex virus 1 infection 💬
2件: IFNAR1, IFNAR2 💬 D03305 💬 Interferon alfa 6件: 13, 25, 26, 28, 56, 96 💬
17 Herpes simplex virus 1 infection 💬
2件: IFNAR1, IFNAR2 💬 D00745 💬 Interferon alfa-2a 1件: 56 💬
18 Herpes simplex virus 1 infection 💬
2件: IFNAR1, IFNAR2 💬 D02745 💬 Interferon alfa-2b 2件: 25, 34 💬
19 Herpes simplex virus 1 infection 💬
2件: IFNAR1, IFNAR2 💬 D04554 💬 Interferon beta-1a 4件: 13, 26, 96, 97 💬
20 Herpes simplex virus 1 infection 💬
2件: IFNAR1, IFNAR2 💬 D00746 💬 Interferon beta-1b 1件: 13 💬
21 Herpes simplex virus 1 infection 💬
2件: IFNAR1, IFNAR2 💬 D10483 💬 Peginterferon beta-1a 1件: 13 💬
22 Herpes simplex virus 1 infection 💬
1件: IFNG 💬 D11120 💬 Emapalumab 2件: 49, 107 💬
23 Herpes simplex virus 1 infection 💬
1件: IFNG 💬 D04242 💬 Fontolizumab 1件: 46 💬
24 Herpes simplex virus 1 infection 💬
2件: IFNGR1, IFNGR2 💬 D00747 💬 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326 💬
25 Herpes simplex virus 1 infection 💬
2件: IL12A, IL12B 💬 D09214 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
26 Herpes simplex virus 1 infection 💬
1件: IL1B 💬 D09315 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
27 Herpes simplex virus 1 infection 💬
1件: IL1B 💬 D09911 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
28 Herpes simplex virus 1 infection 💬
1件: IL1B 💬 D06635 💬 Rilonacept 4件: 51, 106, 107, 266 💬
29 Herpes simplex virus 1 infection 💬
1件: IL6 💬 D09669 💬 Siltuximab 2件: 28, 331 💬
30 Herpes simplex virus 1 infection 💬
1件: IL6 💬 D10080 💬 Sirukumab 2件: 41, 46 💬
31 Herpes simplex virus 1 infection 💬
2件: IL6, TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
32 Herpes simplex virus 1 infection 💬
1件: JAK1 💬 D10871 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬
33 Herpes simplex virus 1 infection 💬
1件: JAK1 💬 D10944 💬 Itacitinib 5件: 46, 51, 60, 97, 228 💬
34 Herpes simplex virus 1 infection 💬
1件: JAK1 💬 D10994 💬 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
35 Herpes simplex virus 1 infection 💬
2件: JAK1, JAK2 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
36 Herpes simplex virus 1 infection 💬
2件: JAK1, JAK2 💬 D10653 💬 Peficitinib 1件: 46 💬
37 Herpes simplex virus 1 infection 💬
2件: JAK1, JAK2 💬 D09959 💬 Ruxolitinib 1件: 228 💬
38 Herpes simplex virus 1 infection 💬
3件: JAK1, JAK2, TYK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
39 Herpes simplex virus 1 infection 💬
1件: LTA 💬 D10187 💬 Pateclizumab 1件: 46 💬
40 Herpes simplex virus 1 infection 💬
2件: LTA, TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
41 Herpes simplex virus 1 infection 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
42 Herpes simplex virus 1 infection 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
43 Herpes simplex virus 1 infection 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
44 Herpes simplex virus 1 infection 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
45 Herpes simplex virus 1 infection 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
46 Herpes simplex virus 1 infection 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
47 Herpes simplex virus 1 infection 💬
1件: PML 💬 D00094 💬 Tretinoin 6件:  2 , 62, 63, 75, 94, 231 💬
48 Herpes simplex virus 1 infection 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
49 Herpes simplex virus 1 infection 💬
1件: SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
50 Herpes simplex virus 1 infection 💬
1件: SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
51 Herpes simplex virus 1 infection 💬
1件: SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
52 Herpes simplex virus 1 infection 💬
1件: SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
53 Herpes simplex virus 1 infection 💬
1件: SYK 💬 D09347 💬 Fostamatinib 4件: 46, 49, 61, 66 💬
54 Herpes simplex virus 1 infection 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
55 Herpes simplex virus 1 infection 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
56 Herpes simplex virus 1 infection 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
57 Herpes simplex virus 1 infection 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
58 Herpes simplex virus 1 infection 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
59 Herpes simplex virus 1 infection 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
60 Herpes simplex virus 1 infection 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
61 Herpes simplex virus 1 infection 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
62 Herpes simplex virus 1 infection 💬
1件: TYK2 💬 D11817 💬 Deucravacitinib 2件: 96, 97 💬